Low expression Macrophage Migration Inhibitory Factor (MIF) alleles and tuberculosis in HIV infected South Africans
Reid D, Shenoi S, Singh R, Wang M, Patel V, Das R, Hiramen K, Moosa Y, Eksteen F, Moll AP, Ndung'u T, Kasprowicz V, Leng L, Friedland GH, Bucala R. Low expression Macrophage Migration Inhibitory Factor (MIF) alleles and tuberculosis in HIV infected South Africans. Cytokine X 2019, 1: 100004. PMID: 33604547, PMCID: PMC7885893, DOI: 10.1016/j.cytox.2019.100004.Peer-Reviewed Original ResearchMacrophage migration inhibitory factorHigh prevalenceCytokine macrophage migration inhibitory factorLow expressionLaboratory-confirmed tuberculosisLow CD4 cellsTB disease casesHIV-positive cohortMigration inhibitory factorPromoter variantsHIV immunosuppressionMIF levelsActive tuberculosisCD4 cellsHIV infectionTB statusClinical informationHost immunityHIVDisease casesInhibitory factorTuberculosisFunctional polymorphismsC SNPGreater frequency