2020
Cutaneous Involvement by Mantle Cell Lymphoma: Expanding the Spectrum of Histopathologic Findings in a Series of 9 Cases.
Panse G, Cowper S, Ko CJ, Subtil A. Cutaneous Involvement by Mantle Cell Lymphoma: Expanding the Spectrum of Histopathologic Findings in a Series of 9 Cases. American Journal Of Dermatopathology 2020, 42: 848-853. PMID: 32675465, DOI: 10.1097/dad.0000000000001742.Peer-Reviewed Case Reports and Technical NotesConceptsMantle cell lymphomaCutaneous involvementCell lymphomaSystemic mantle cell lymphomaAggressive B-cell neoplasmSingle institutional seriesSame biopsy specimenSite of involvementMarginal zone lymphomaB-cell neoplasmsImmunoglobulin M expressionSurface IgM expressionInstitutional seriesSecond malignanciesSystemic involvementClinicopathologic featuresCutaneous lesionsSitu hybridization studiesBiopsy specimenHistopathologic findingsMetastatic melanomaFirst manifestationDirect immunofluorescenceHematolymphoid neoplasmsTissue manifestations
2019
Lobular neutrophilic panniculitis associated with DNA methyltransferase inhibitors in the treatment of myeloid disease
Coleman E, Panse G, Cowper S, Prebet T, Gore S, Leventhal J. Lobular neutrophilic panniculitis associated with DNA methyltransferase inhibitors in the treatment of myeloid disease. Journal Of Cutaneous Pathology 2019, 46: 930-934. PMID: 31254406, DOI: 10.1111/cup.13537.Peer-Reviewed Original ResearchConceptsLobular neutrophilic panniculitisNeutrophilic panniculitisDNA methyltransferase inhibitorNeutrophilic eccrine hidradenitisInjection site reactionsAcute myelogenous leukemiaMethyltransferase inhibitorNeutrophilic dermatosisSweet's syndromeMaculopapular eruptionCutaneous toxicityHistopathologic characteristicsSite reactionsNext-generation agentsDifferential diagnosisMyelogenous leukemiaTreatment considerationsMyeloid diseasesPanniculitisTreatmentInhibitorsFirst reportGangrenosumHidradenitisEcchymosis
2018
Erythema Nodosum–like Eruption in the Setting of Sorafenib Therapy
Coleman EL, Cowper SE, Stein SM, Leventhal JS. Erythema Nodosum–like Eruption in the Setting of Sorafenib Therapy. JAMA Dermatology 2018, 154: 369-370. PMID: 29453869, DOI: 10.1001/jamadermatol.2017.5733.Peer-Reviewed Case Reports and Technical Notes
2017
A 71‐year‐old man with a hemorrhagic vesicular eruption
Hamilton CE, King BA, Cowper SE, Hochster H, Leventhal JS. A 71‐year‐old man with a hemorrhagic vesicular eruption. International Journal Of Dermatology 2017, 57: 147-148. PMID: 29057466, DOI: 10.1111/ijd.13793.Peer-Reviewed Case Reports and Technical NotesWell‐differentiated neuroendocrine tumors in skin: Terminology and diagnostic utility of cytokeratin 5/6 and p63
Panse G, Cowper SE, Leffell DJ, Pulitzer M, Ko CJ. Well‐differentiated neuroendocrine tumors in skin: Terminology and diagnostic utility of cytokeratin 5/6 and p63. Journal Of Cutaneous Pathology 2017, 44: 557-562. PMID: 28417484, DOI: 10.1111/cup.12952.Peer-Reviewed Original ResearchConceptsCutaneous adnexal neoplasmsAdnexal neoplasmsNeuroendocrine tumorsAdnexal tumorsBenign skin adnexal tumorCutaneous adnexal tumorsAggressive metastatic diseaseLow-grade tumorsSkin adnexal tumorsMajority of casesMetastatic diseaseMetastatic adenocarcinomaCarcinoid tumorsCytokeratin 5/6Diagnostic challengeDifferential diagnosisImmunohistochemical stainsCK5/6Diagnostic utilityPrimary siteTumorsNeoplasmsFirst signWDNETsP63
2014
Diagnosing nephrogenic systemic fibrosis in the post‐FDA restriction era
Thomson LK, Thomson PC, Kingsmore DB, Blessing K, Daly CD, Cowper SE, Roditi GH. Diagnosing nephrogenic systemic fibrosis in the post‐FDA restriction era. Journal Of Magnetic Resonance Imaging 2014, 41: 1268-1271. PMID: 24903851, DOI: 10.1002/jmri.24664.Peer-Reviewed Original Research
2007
Nephrogenic systemic fibrosis: a case series suggesting gadolinium as a possible aetiological factor
Moreno‐Romero J, Segura S, Mascaró JM, Cowper SE, Julià M, Poch E, Botey A, Herrero C. Nephrogenic systemic fibrosis: a case series suggesting gadolinium as a possible aetiological factor. British Journal Of Dermatology 2007, 157: 783-787. PMID: 17627792, DOI: 10.1111/j.1365-2133.2007.08067.x.Peer-Reviewed Original ResearchConceptsNephrogenic systemic fibrosisDevelopment of NSFRenal insufficiency patientsOnset of symptomsNephrogenic fibrosing dermopathyPossible aetiological factorsMagnetic resonance angiographyRenal diseaseCase seriesAetiological factorsSystemic fibrosisResonance angiographyFibrotic conditionsPatientsParamagnetic contrast agentHistory of useDiseaseContrast agentsAngiographyFibrosisDermopathyEtiologyGadoliniumSymptomsNephrogenic Systemic Fibrosis: A Population Study Examining the Relationship of Disease Development to Gadolinium Exposure
Deo A, Fogel M, Cowper SE. Nephrogenic Systemic Fibrosis: A Population Study Examining the Relationship of Disease Development to Gadolinium Exposure. Clinical Journal Of The American Society Of Nephrology 2007, 2: 264-267. PMID: 17699423, DOI: 10.2215/cjn.03921106.Peer-Reviewed Original ResearchConceptsNephrogenic systemic fibrosisGadolinium-containing contrast agentsGadolinium exposureIncidence of NSFSevere renal failurePopulation of patientsMajor risk factorOccurrence of NSFDevastating complicationESRD populationRenal failureSignificant morbidityRadiologic studiesRisk factorsSystemic fibrosisPopulation studiesESRDPatientsDisease developmentRecent reportsExposureContrast agentsRiskMorbidityComplications
2005
CD56 staining in Merkel cell carcinoma and natural killer‐cell lymphoma: magic bullet, diagnostic pitfall, or both?
McNiff JM, Cowper SE, Lazova R, Subtil A, Glusac EJ. CD56 staining in Merkel cell carcinoma and natural killer‐cell lymphoma: magic bullet, diagnostic pitfall, or both? Journal Of Cutaneous Pathology 2005, 32: 541-545. PMID: 16115052, DOI: 10.1111/j.0303-6987.2005.00378.x.Peer-Reviewed Original ResearchConceptsNatural killer cell lymphomaNK-cell lymphomasMerkel cell carcinomaCases of MCCCD56 positivityCell carcinomaDiagnostic pitfallsDiagnosis of lymphomaCD20 negativityDense inflammationInflamed biopsiesNK lymphomaHistologic featuresMagic bulletNeuroendocrine tumorsCell lymphomaCD56Crush artifactSensitive markerLymphomaAdditional casesCarcinomaPositivityCK20MNF116Cellular digital fibromas: distinctive CD34‐positive lesions that may mimic dermatofibrosarcoma protuberans
McNiff JM, Subtil A, Cowper SE, Lazova R, Glusac EJ. Cellular digital fibromas: distinctive CD34‐positive lesions that may mimic dermatofibrosarcoma protuberans. Journal Of Cutaneous Pathology 2005, 32: 413-418. PMID: 15953374, DOI: 10.1111/j.0303-6987.2005.00358.x.Peer-Reviewed Original Research
2003
Nephrogenic fibrosing dermopathy: the first 6 years
Cowper SE. Nephrogenic fibrosing dermopathy: the first 6 years. Current Opinion In Rheumatology 2003, 15: 785-790. PMID: 14569211, DOI: 10.1097/00002281-200311000-00017.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsNephrogenic fibrosing dermopathyRecent case reportsCase reportCutaneous fibrosing disorderYellow scleral plaquesDistinct clinical patternsDual immunohistochemical stainingAntiphospholipid antibodiesRenal insufficiencyClinical patternDual immunolabelingFibrosing disorderSystemic disordersClinical spectrumScleral plaquesDisease onsetEpidemiologic dataSpindle cellsImmunohistochemical stainingDisease triggersSkin conditionsDisease pathogenesisNormal skinRegistry projectDiagnostic tests
2002
An Investigation of Apoptosis in Androgenetic Alopecia
Cowper SE, Rosenberg AS, Morgan MB. An Investigation of Apoptosis in Androgenetic Alopecia. American Journal Of Dermatopathology 2002, 24: 204-208. PMID: 12140435, DOI: 10.1097/00000372-200206000-00003.Peer-Reviewed Original Research
2001
Nephrogenic Fibrosing Dermopathy
Cowper S, Su L, Bhawan J, Robin H, LeBoit P. Nephrogenic Fibrosing Dermopathy. American Journal Of Dermatopathology 2001, 23: 383-393. PMID: 11801769, DOI: 10.1097/00000372-200110000-00001.Peer-Reviewed Original ResearchConceptsNephrogenic fibrosing dermopathyElastic fibersPositive dermal dendrocytesCollagen bundlesDifferent kidney diseasesThick collagen bundlesRenal transplantCutaneous changesDendritic cellsFibrosing disorderRenal diseaseSystemic findingsIndurated plaquesDermal mucinKidney diseaseSingle institutionDermal dendrocytesDialysis centersHistopathologic examinationHistopathologic findingsRenal dialysisEntire dermisSpindle cellsEarly lesionsRoutine microscopy
2000
Scleromyxoedema-like cutaneous diseases in renal-dialysis patients
Cowper S, Robin H, Steinberg S, Su L, Gupta S, LeBoit P. Scleromyxoedema-like cutaneous diseases in renal-dialysis patients. The Lancet 2000, 356: 1000-1001. PMID: 11041404, DOI: 10.1016/s0140-6736(00)02694-5.Commentaries, Editorials and Letters
1999
Expression of p-27 (kip1) in Nevi and Melanomas
Morgan M, Cowper S. Expression of p-27 (kip1) in Nevi and Melanomas. American Journal Of Dermatopathology 1999, 21: 121-124. PMID: 10218670, DOI: 10.1097/00000372-199904000-00002.Peer-Reviewed Original ResearchConceptsExpression of p27Melanocytic lesionsSpitz neviDistribution of immunoreactivityP27 labeling indexMinority of casesCell cycle inhibitory proteinsChart reviewMalignant melanocytic lesionsClinical historyDiagnostic challengeBiologic behaviorHistopathologic criteriaLabeling indexCompound neviLogistic regressionHuman neoplasmsNeviNuclear stainingLesionsMelanomaP27Inhibitory proteinAccurate distinctionSkin