2008
Preoperative β-blocker use: impact of national guidelines on clinical practice
Akhtar S, Assaad, Amin M, Holt NF, Barash PG, Silverman DG. Preoperative β-blocker use: impact of national guidelines on clinical practice. Journal Of Clinical Anesthesia 2008, 20: 122-128. PMID: 18410867, DOI: 10.1016/j.jclinane.2007.09.012.Peer-Reviewed Original ResearchConceptsBeta-blocker groupPost-guideline patientsPre-guideline groupVascular surgery patientsCoronary artery bypassTarget HRArtery bypassSurgery patientsPerioperative beta-blocker therapyPreoperative beta-blocker useTertiary care teaching hospitalMean HRElective vascular surgeryPost-guideline groupVascular surgery groupBeta-blocker therapyBeta-blocker useUnpaired t-testEligible patientsSurgery groupPreanesthetic evaluationVascular surgeryPresurgical patientsTeaching hospitalObservational study
2005
Preoperative β-blocker use: is titration to a heart rate of 60 beats per minute a consistently attainable goal?
Akhtar S, Amin M, Tantawy H, Senior A, Barash PG, Silverman DG. Preoperative β-blocker use: is titration to a heart rate of 60 beats per minute a consistently attainable goal? Journal Of Clinical Anesthesia 2005, 17: 191-197. PMID: 15896586, DOI: 10.1016/j.jclinane.2004.06.020.Peer-Reviewed Original ResearchConceptsPreinduction heart ratePerioperative beta-blocker useBeta-blocker useHeart rateCABG patientsEligible patientsSurgery patientsCoronary artery bypass graft surgeryArtery bypass graft surgeryTertiary care teaching hospitalBeta-blocker intoleranceCABG surgery patientsBeta-blocker therapyBypass graft surgeryVascular surgery patientsRetrospective observational studyUnpaired t-testBlocker groupGraft surgeryNoncardiac surgeryVascular patientsVascular surgeryTeaching hospitalObservational studyCurrent recommendations
1999
The Effect of Heart Rate Control on Myocardial Ischemia Among High-Risk Patients After Vascular Surgery
Raby K, Brull S, Timimi F, Akhtar S, Rosenbaum S, Naimi C, Whittemore A. The Effect of Heart Rate Control on Myocardial Ischemia Among High-Risk Patients After Vascular Surgery. Anesthesia & Analgesia 1999, 88: 477-482.. DOI: 10.1213/00000539-199903000-00002.Peer-Reviewed Original ResearchConceptsHeart rate controlMean heart ratePostoperative cardiac eventsHigh-risk patientsST-segment depressionIschemic thresholdPostoperative ischemiaMyocardial ischemiaVascular surgeryHeart rateCardiac eventsEsmolol patientsPlacebo patientsPreoperative ischemiaCardiac complicationsHigh riskHigh-risk vascular surgery patientsBeta-adrenergic blocker therapyMajor postoperative cardiac eventsStrict heart rate controlElective vascular surgeryIncidence of ischemiaPostoperative heart ratePostoperative myocardial ischemiaPreoperative myocardial ischemiaThe effect of heart rate control on myocardial ischemia among high-risk patients after vascular surgery.
Raby K, Brull S, Timimi F, Akhtar S, Rosenbaum S, Naimi C, Whittemore A. The effect of heart rate control on myocardial ischemia among high-risk patients after vascular surgery. Anesthesia & Analgesia 1999, 88: 477-82. PMID: 10071990, DOI: 10.1097/00000539-199903000-00002.Peer-Reviewed Original ResearchConceptsHeart rate controlMean heart ratePostoperative cardiac eventsHigh-risk patientsST-segment depressionIschemic thresholdPostoperative ischemiaMyocardial ischemiaVascular surgeryHeart rateCardiac eventsEsmolol patientsPlacebo patientsPreoperative ischemiaCardiac complicationsHigh riskHigh-risk vascular surgery patientsBeta-adrenergic blocker therapyMajor postoperative cardiac eventsStrict heart rate controlElective vascular surgeryIncidence of ischemiaPostoperative heart ratePostoperative myocardial ischemiaPreoperative myocardial ischemia