2009
ORIGINAL ARTICLE: Regulation of Nod1 and Nod2 in First Trimester Trophoblast Cells
Mulla MJ, Yu AG, Cardenas I, Guller S, Panda B, Abrahams VM. ORIGINAL ARTICLE: Regulation of Nod1 and Nod2 in First Trimester Trophoblast Cells. American Journal Of Reproductive Immunology 2009, 61: 294-302. PMID: 19260860, DOI: 10.1111/j.1600-0897.2009.00694.x.Peer-Reviewed Original ResearchMeSH KeywordsApoptosisBenzamidesCells, CulturedCytokinesDiaminopimelic AcidFemaleGene Expression Regulation, DevelopmentalHumansLipopolysaccharidesNF-kappa BNod1 Signaling Adaptor ProteinNod2 Signaling Adaptor ProteinPregnancyPregnancy Trimester, FirstSequence DeletionSignal TransductionThiazolesToll-Like Receptor 4TransgenesTrophoblastsConceptsFirst trimester trophoblast cellsTrophoblast cellsExpression of NOD1Cytoplasmic pattern recognition receptorsProduction of cytokinesNOD2 mRNA expressionPattern recognition receptorsNOD2 expressionCytokine responsesInflammatory responseNOD2 activationNOD1 activationNFkappaB inhibitorRecognition receptorsNOD1Nod1 stimulationNOD2Bacterial lipopolysaccharideMRNA expressionTLR4LipopolysaccharideNFkappaB pathwayRT-PCRBacterial peptidesTrophoblast
2004
Differential Effects of Lipopolysaccharide and Thrombin on Interleukin‐8 Expression in Syncytiotrophoblasts and Endothelial Cells: Implications for Fetal Survival
MA Y, KADNER SS, GULLER S. Differential Effects of Lipopolysaccharide and Thrombin on Interleukin‐8 Expression in Syncytiotrophoblasts and Endothelial Cells: Implications for Fetal Survival. Annals Of The New York Academy Of Sciences 2004, 1034: 236-244. PMID: 15731315, DOI: 10.1196/annals.1335.025.Peer-Reviewed Original ResearchConceptsCytokine expressionEndothelial cellsFetal survivalInfection-associated changesPlacental cytokine expressionTissue factor-initiated blood coagulationIL-8 levelsInterleukin-8 levelsAnti-inflammatory steroidsMaintenance of pregnancyIL-8 expressionIL-8 mRNAInterleukin-8 expressionEffect of thrombinHuman umbilical vein endothelial cellsHuman term placentaUmbilical vein endothelial cellsVein endothelial cellsCytokine responsesCytokine productionProinflammatory processesIL-8Inflammatory responseLPS treatmentIntervillous space