2017
Dynamics of Base Excision Repair at the Maternal–Fetal Interface in Pregnancies Complicated by Preeclampsia
Tadesse S, Norwitz NG, Guller S, Arcuri F, Toti P, Norwitz ER, Kidane D. Dynamics of Base Excision Repair at the Maternal–Fetal Interface in Pregnancies Complicated by Preeclampsia. Reproductive Sciences 2017, 24: 856-864. PMID: 27707956, DOI: 10.1177/1933719116670519.Peer-Reviewed Original ResearchConceptsMaternal-fetal interfaceOxidative stressNormotensive controlsPlacental tissueHypoxia/reperfusion (H/R) modelPlacental endothelial dysfunctionPlacentas of womenHealthy control subjectsApyrimidinic endonuclease 1PE placental tissuesPregnancy ComplicatedEndothelial dysfunctionPreeclamptic womenPerinatal mortalityReperfusion modelControl subjectsDecidual cellsPathological basisVivo comparative studyPreeclampsiaMaternal cellsFetal cellsAPE1 expressionSignificant increaseWomen
2003
Circulating soluble Fas levels and risk of ovarian cancer
Akhmedkhanov A, Lundin E, Guller S, Lukanova A, Micheli A, Ma Y, Afanasyeva Y, Zeleniuch-Jacquotte A, Krogh V, Lenner P, Muti P, Rinaldi S, Kaaks R, Berrino F, Hallmans G, Toniolo P. Circulating soluble Fas levels and risk of ovarian cancer. BMC Cancer 2003, 3: 33. PMID: 14690548, PMCID: PMC317312, DOI: 10.1186/1471-2407-3-33.Peer-Reviewed Original ResearchConceptsSerum sFas levelsSerum sFasOvarian cancerSFas levelsPrimary invasive epithelial ovarian cancerQuantitative sandwich enzyme immunoassayInvasive epithelial ovarian cancerSoluble Fas levelsEpithelial ovarian cancerIdentification of womenOvarian cancer riskCase-control studySandwich enzyme immunoassayMenopausal statusProspective cohortEnrollment datePotential confoundersControl subjectsSoluble FasMethodsThe associationCancer riskCase subjectsHighest thirdBlood donationPotential biomarkers