2016
Neurologic signs and symptoms frequently manifest in acute HIV infection
Hellmuth J, Fletcher JL, Valcour V, Kroon E, Ananworanich J, Intasan J, Lerdlum S, Narvid J, Pothisri M, Allen I, Krebs SJ, Slike B, Prueksakaew P, Jagodzinski LL, Puttamaswin S, Phanuphak N, Spudich S, Phanuphak P, Phanuphak N, Colby D, Chalermchai T, Chomchey N, Suttichom D, Rattanamanee S, Sangtawan P, Rattanamanee S, Nuntapinit B, Rakyat P, Inprakong S, Lucksanawong S, Ruangjan P, Nuchwong A, Kruacharoen P, O’Connell R, Adams C, Clifford K, Wendelken L, Le L, Mistry H, Tovanabutra S, Pinyakorn S, Robb M, Paul R. Neurologic signs and symptoms frequently manifest in acute HIV infection. Neurology 2016, 87: 148-154. PMID: 27287217, PMCID: PMC4940060, DOI: 10.1212/wnl.0000000000002837.Peer-Reviewed Original ResearchConceptsCombination antiretroviral therapyAcute HIV infectionNeurologic findingsHIV infectionAcute HIVNeurologic manifestationsNeurologic evaluationHIV infection durationLog10 HIV RNASevere neurologic manifestationsStructural neuroimaging abnormalitiesCART initiationAntiretroviral therapyHIV RNAInflammatory markersMotor findingsNeuroimaging abnormalitiesStudy entryNeurologic signsBrain MRIInfection durationCognitive symptomsViral factorsInfectionDiagnosis
2015
CROI 2015: Neurologic Complications of HIV Infection.
Spudich SS, Ances BM. CROI 2015: Neurologic Complications of HIV Infection. Topics In Antiviral Medicine 2015, 23: 47-55. PMID: 25965311, PMCID: PMC6148901.Peer-Reviewed Original ResearchConceptsCentral nervous systemModifiable risk factorsPathogenesis of HIVQuality of lifeBiomarkers of HANDResource-limited settingsNeurologic complicationsNeurologic presentationHIV infectionCNS reservoirsOpportunistic infectionsRisk factorsHIV epidemicCNS disordersCognitive dysfunctionNeurocognitive disordersHIVNervous systemInfectionDisordersCollaborative studyComplicationsDysfunctionPathogenesisDiagnosis