2001
Investigation of adenosine base ionization in the hairpin ribozyme by nucleotide analog interference mapping.
Ryder S, Oyelere A, Padilla J, Klostermeier D, Millar D, Strobel S. Investigation of adenosine base ionization in the hairpin ribozyme by nucleotide analog interference mapping. RNA 2001, 7: 1454-63. PMID: 11680850, PMCID: PMC1370189.Peer-Reviewed Original Research
2000
A Single Adenosine with a Neutral pKa in the Ribosomal Peptidyl Transferase Center
Muth G, Ortoleva-Donnelly L, Strobel S. A Single Adenosine with a Neutral pKa in the Ribosomal Peptidyl Transferase Center. Science 2000, 289: 947-950. PMID: 10937997, DOI: 10.1126/science.289.5481.947.Peer-Reviewed Original Research
1999
Nucleotide Analog Interference Mapping
Ryder S, Strobel S. Nucleotide Analog Interference Mapping. Methods 1999, 18: 38-50. PMID: 10208815, DOI: 10.1006/meth.1999.0755.Peer-Reviewed Original ResearchConceptsFunctional groupsActive moleculesGroup substitutionNucleotide analog interference mappingIncorporation propertiesIndividual analoguesMoleculesSeries 5AnaloguesSubstitution experimentsGel electrophoresisInterference mappingUnique biochemical signatureSubstitutionSynthesisNucleoside analog triphosphatesActivity assaysBiochemical informationReactionAnalog substitutionsAssayable functionChemogenetic approachRNA structureNucleotide analoguesIodine
1998
The chemical basis of adenosine conservation throughout the Tetrahymena ribozyme.
Ortoleva-Donnelly L, Szewczak A, Gutell R, Strobel S. The chemical basis of adenosine conservation throughout the Tetrahymena ribozyme. RNA 1998, 4: 498-519. PMID: 9582093, PMCID: PMC1369635, DOI: 10.1017/s1355838298980086.Peer-Reviewed Original Research
1995
The branch site adenosine is recognized differently for the two steps of pre-mRNA splicing.
Query C, Strobel S, Sharp P. The branch site adenosine is recognized differently for the two steps of pre-mRNA splicing. Nucleic Acids Symposium Series 1995, 224-5. PMID: 8643377.Peer-Reviewed Original Research