Reduced Subjective Response to Acute Ethanol Administration Among Young Men with a Broad Bipolar Phenotype
Yip SW, Doherty J, Wakeley J, Saunders K, Tzagarakis C, de Wit H, Goodwin GM, Rogers RD. Reduced Subjective Response to Acute Ethanol Administration Among Young Men with a Broad Bipolar Phenotype. Neuropsychopharmacology 2012, 37: 1808-1815. PMID: 22491350, PMCID: PMC3376329, DOI: 10.1038/npp.2012.45.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentBehavior, AddictiveBipolar DisorderCentral Nervous System DepressantsDouble-Blind MethodEthanolHumansMalePhenotypePsychiatric Status Rating ScalesYoung AdultConceptsAlcohol use disorderWeekly alcohol intakeBipolar disorderAlcohol intakeSubjective responsesAcute ethanol administrationLifetime prevalence ratesDevelopment of AUDPlacebo administrationAcute alcoholEthanol administrationHealthy controlsSedative responsePharmacokinetic effectsEtiological factorsPrevalence ratesUse disordersAlcohol misusePharmacokinetic responseFamilial riskAlcohol responsesYoung malesIntoxication effectsBipolar phenotypeYoung men