2019
Gambling disorder
Potenza MN, Balodis IM, Derevensky J, Grant JE, Petry NM, Verdejo-Garcia A, Yip SW. Gambling disorder. Nature Reviews Disease Primers 2019, 5: 51. PMID: 31346179, DOI: 10.1038/s41572-019-0099-7.Peer-Reviewed Original ResearchConceptsPlacebo-controlled trialOpioid receptor antagonistGambling disorderCognitive behavioral therapyPharmacological therapyLimbic structuresPsychiatric disordersAdult populationSubstantial distressClinical settingBehavioral interventionsTreatment effortsDisordersTherapyPoor qualityFormal indicationNeurobiological studiesTreatmentImproved identificationMedicationsPathophysiologyEtiologyAntagonistPrevalenceGamblers Anonymous
2018
The Cholinergic System as a Treatment Target for Opioid Use Disorder
Jensen KP, DeVito EE, Yip S, Carroll KM, Sofuoglu M. The Cholinergic System as a Treatment Target for Opioid Use Disorder. CNS Drugs 2018, 32: 981-996. PMID: 30259415, PMCID: PMC6314885, DOI: 10.1007/s40263-018-0572-y.Peer-Reviewed Original ResearchConceptsCholinergic systemUse disordersTreatment targetsOpioid use disorder epidemicCentral nervous system functionTreatment of OUDEffects of acetylcholineOpioid use disorderTobacco use disorderNervous system functionOpioid medicationsDegrade acetylcholineCurrent treatmentOpioid overdosesPreclinical studiesMedicationsAcetylcholineCholinesterase inhibitorsAlzheimer's diseaseNew treatmentsAccidental deathGlobal healthTreatmentOUDDisease