2024
A shared spatial topography links the functional connectome correlates of cocaine use disorder and dopamine D2/3 receptor densities
Ricard J, Labache L, Segal A, Dhamala E, Cocuzza C, Jones G, Yip S, Chopra S, Holmes A. A shared spatial topography links the functional connectome correlates of cocaine use disorder and dopamine D2/3 receptor densities. Communications Biology 2024, 7: 1178. PMID: 39300138, PMCID: PMC11413242, DOI: 10.1038/s42003-024-06836-9.Peer-Reviewed Original ResearchConceptsCocaine use disorderPatterns of functional connectivityUse disorderFunctional connectivityReceptor densityLarge-scale functional brain networksMaintenance of substance useDopamine D2/3 receptorsDopamine receptor densityCortico-striatal circuitsProfile of functional connectivitySubstance use disordersFunctional brain networksNeurotransmitter receptor densityD2/3 receptorsDopamine systemTransporter bindingSubcortical systemsBrain networksSubstance useCocaineSpatial topographyDisordersDopamineBiological mechanisms
2021
Effects of Smoking Status and State on Intrinsic Connectivity
Yip SW, Lichenstein SD, Garrison K, Averill CL, Viswanath H, Salas R, Abdallah CG. Effects of Smoking Status and State on Intrinsic Connectivity. Biological Psychiatry Cognitive Neuroscience And Neuroimaging 2021, 7: 895-904. PMID: 33618016, PMCID: PMC8373998, DOI: 10.1016/j.bpsc.2021.02.004.Peer-Reviewed Original ResearchConceptsSmoking statusIntrinsic connectivityResting-state functional magnetic resonance imagingDefault mode connectivityIntrinsic connectivity distributionLong-term abstinenceFunctional magnetic resonance imagingMagnetic resonance imagingResting-state scanWhole-brain patternsControl nonsmokersSmoking reinstatementInterest-based analysisTobacco smokersFunctional connectivity dataTobacco abstinenceQuit attemptsOvernight abstinenceTobacco deprivationNovel treatmentsSmoking behaviorEarly abstinenceResonance imagingSalience networkFunctional connectivity
2017
Altered functional connectivity to stressful stimuli in prenatally cocaine-exposed adolescents
Zakiniaeiz Y, Yip SW, Balodis IM, Lacadie CM, Scheinost D, Constable RT, Mayes LC, Sinha R, Potenza MN. Altered functional connectivity to stressful stimuli in prenatally cocaine-exposed adolescents. Drug And Alcohol Dependence 2017, 180: 129-136. PMID: 28888152, PMCID: PMC5808433, DOI: 10.1016/j.drugalcdep.2017.07.030.Peer-Reviewed Original ResearchConceptsPrenatal cocaine exposureNeutral-relaxing conditionsPCE adolescentsParietal connectivityConnectivity analysisSensory areasAdolescent brain functionFunctional magnetic resonance imagingCue interaction effectsIntrinsic connectivity analysesMedial prefrontal areasSeed-based connectivity analysisSubstance Use InitiationAltered functional connectivityAppetitive cuesObesity vulnerabilityPCE statusNeural responsesCorticolimbic connectivityPrefrontal areasFunctional connectivityCraving scoresUtero drug exposureGroup differencesLess connectivity