Featured Publications
Metabolic Syndrome, Exercise, and Cardiovascular Fitness in Breast Cancer Survivors
Knobf MT, Jeon S. Metabolic Syndrome, Exercise, and Cardiovascular Fitness in Breast Cancer Survivors. Journal Of The Advanced Practitioner In Oncology 2020, 11: 98-102. PMID: 33542853, PMCID: PMC7517769, DOI: 10.6004/jadpro.2020.11.1.6.Peer-Reviewed Original ResearchBreast cancer survivorsCancer survivorsRisk factorsMetabolic syndromeBlood sugarCardiovascular fitnessMetS risk factorsRisk of comorbiditiesSystolic blood pressurePhysical activity groupEffects of exerciseOncology Advanced PractitionersPoor cancer outcomesRoutine physical activityHigh-density lipoproteinIndividual risk factorsComorbid illnessesExercise interventionMetS riskBlood pressureWaist circumferenceOncology patientsCancer outcomesSubset analysisPhysical activity
2017
The Yale Fitness Intervention Trial in female cancer survivors: Cardiovascular and physiological outcomes
Knobf MT, Jeon S, Smith B, Harris L, Thompson S, Stacy MR, Insogna K, Sinusas AJ. The Yale Fitness Intervention Trial in female cancer survivors: Cardiovascular and physiological outcomes. Heart & Lung 2017, 46: 375-381. PMID: 28803675, PMCID: PMC6129386, DOI: 10.1016/j.hrtlng.2017.06.001.Peer-Reviewed Original ResearchConceptsFemale cancer survivorsCancer survivorsCenter interventionMET-minutes/weekStable insulin levelsMetabolic risk factorsResistance exercise programExercise stress testCardiovascular disease riskPhysical activity groupImproved insulin resistanceHeart rate recoveryMinutes/weekRisk reduction interventionsMajority of subjectsAdjuvant chemotherapyPremature menopauseExercise programInsulin levelsInsulin resistanceIntervention trialsRisk factorsCardiovascular functionBreast cancerRate recoveryExercise, metabolic syndrome, and cardiovascular fitness in breast cancer survivors.
Knobf M, Sinusas A, Holland M, Jeon S. Exercise, metabolic syndrome, and cardiovascular fitness in breast cancer survivors. Journal Of Clinical Oncology 2017, 35: 165-165. DOI: 10.1200/jco.2017.35.5_suppl.165.Peer-Reviewed Original ResearchBreast cancer survivorsPhysical activity groupHeart rate recoveryMetabolic syndromeCancer survivorsLifestyle behaviorsCardiovascular diseaseRate recoveryCardiovascular fitnessAge-matched postmenopausal womenBreast cancer-specific mortalityActivity groupHigh baseline incidenceCancer-specific mortalityFirst-line interventionCause mortalityEndocrine therapyPostmenopausal womenExercise interventionMetS componentsMetS criteriaDiastolic BPSystolic BPMonths interventionMetabolic outcomes
2016
Effect of a randomized controlled exercise trial on bone outcomes: influence of adjuvant endocrine therapy
Knobf MT, Jeon S, Smith B, Harris L, Kerstetter J, Thompson AS, Insogna K. Effect of a randomized controlled exercise trial on bone outcomes: influence of adjuvant endocrine therapy. Breast Cancer Research And Treatment 2016, 155: 491-500. PMID: 26850265, DOI: 10.1007/s10549-016-3693-3.Peer-Reviewed Original ResearchConceptsFemale cancer survivorsPhysical activity groupEndocrine therapyBone outcomesExercise interventionBone lossFemoral neckAromatase inhibitorsActivity groupAdjuvant AI therapyChemotherapy-induced menopauseSufficient serum levelsAdjuvant endocrine therapyVitamin D supplementsHealthy postmenopausal womenLess bone lossHome-based groupSignificant BMD lossSignificant clinical problemMajority of subjectsAI therapyD supplementsPostmenopausal womenBMD lossBMD outcomes