Symptom cluster profiles following traumatic orthopedic injuries: A protocol
Breazeale S, Dorsey SG, Kearney J, Conley S, Jeon S, Yoo B, Redeker NS. Symptom cluster profiles following traumatic orthopedic injuries: A protocol. Research In Nursing & Health 2020, 44: 268-278. PMID: 33368378, PMCID: PMC7933085, DOI: 10.1002/nur.22102.Peer-Reviewed Original ResearchConceptsBrain-derived neurotrophic factorTraumatic orthopaedic injuriesStressor-related disordersSerum concentrationsSleep disturbancesOrthopedic injuriesLong-term outcomesCross-sectional studyVal66Met mutationLow serum concentrationsSymptoms of anxietyPotential biological mechanismsPostinjury symptomsClinical factorsNegative long-term outcomesNeurotrophic factorBDNF geneTraumatic injuryHigh riskMillions of AmericansHealthcare costsMore symptomsInjurySymptomsPain