Symptom cluster profiles following traumatic orthopaedic injuries
Breazeale S, Conley S, Jeon S, Dorsey SG, Kearney J, Yoo B, Redeker NS. Symptom cluster profiles following traumatic orthopaedic injuries. Injury 2022, 53: 2524-2532. PMID: 35351294, PMCID: PMC9232974, DOI: 10.1016/j.injury.2022.03.030.Peer-Reviewed Original ResearchConceptsBrain-derived neurotrophic factorSerum BDNF concentrationsTraumatic orthopaedic injuriesAcute stress disorderBDNF concentrationsEnzyme-linked immunosorbent assayRs6265 genotypeClinical characteristicsOrthopedic injuriesSymptoms of ASDOutcomes Measurement Information System Short FormsSelf-identified black raceAcute Stress Disorder ScaleHours of injuryPost-injury symptomsSevere psychological distressSymptoms of anxietySymptom burdenSymptom screeningNeurotrophic factorBlack raceFemale sexSleep disturbancesReal-time PCRHigher odds