Salinomycin simultaneously induces apoptosis and autophagy through generation of reactive oxygen species in osteosarcoma U2OS cells
Kim S, Choi Y, Kim K, Yu S, Seo Y, Chun S, Noh K, Suh J, Ahn S. Salinomycin simultaneously induces apoptosis and autophagy through generation of reactive oxygen species in osteosarcoma U2OS cells. Biochemical And Biophysical Research Communications 2016, 473: 607-613. PMID: 27033598, DOI: 10.1016/j.bbrc.2016.03.132.Peer-Reviewed Original ResearchConceptsAcidic vesicular organellesReactive oxygen speciesMitochondrial membrane potentialChange of MMPOsteosarcoma U2OS cellsInhibition of autophagyU2OS cellsExpression of apoptosisCancer cell linesOxygen speciesFlow cytometryWestern blottingCaspase-3Cancer therapyVesicular organellesPoly (ADP-ribose) polymerase