2010
Multisite effectiveness trials of treatments for substance abuse and co-occurring problems: Have we chosen the best designs?
Nunes EV, Ball S, Booth R, Brigham G, Calsyn DA, Carroll K, Feaster DJ, Hien D, Hubbard RL, Ling W, Petry NM, Rotrosen J, Selzer J, Stitzer M, Tross S, Wakim P, Winhusen T, Woody G. Multisite effectiveness trials of treatments for substance abuse and co-occurring problems: Have we chosen the best designs? Journal Of Substance Use And Addiction Treatment 2010, 38: s97-s112. PMID: 20307801, PMCID: PMC2909698, DOI: 10.1016/j.jsat.2010.01.012.Peer-Reviewed Original ResearchMeSH KeywordsCommunity Health ServicesComparative Effectiveness ResearchEvidence-Based MedicineHumansInformation DisseminationNational Institute on Drug Abuse (U.S.)Randomized Controlled Trials as TopicResearch DesignSubstance Abuse Treatment CentersSubstance-Related DisordersTreatment OutcomeUnited StatesConceptsClinical Trials NetworkMultisite effectiveness trialEffectiveness trialNational Drug Abuse Treatment Clinical Trials NetworkSubstance abuseNew interventionsReal-world clinical settingNew treatment interventionsPrimary outcome paperFuture effectiveness trialHIV risk behaviorsEvidence-based treatmentsBehavioral health problemsCo-occurring problemsOutcome papersClinical trialsHIV riskTreatment interventionsHealth problemsRisk behaviorsClinical settingTrials NetworkDrug abuseTrialsSuch treatment
2008
Serious Adverse Events in Randomized Psychosocial Treatment Studies: Safety or Arbitrary Edicts?
Petry NM, Roll JM, Rounsaville BJ, Ball SA, Stitzer M, Peirce JM, Blaine J, Kirby KC, McCarty D, Carroll KM. Serious Adverse Events in Randomized Psychosocial Treatment Studies: Safety or Arbitrary Edicts? Journal Of Consulting And Clinical Psychology 2008, 76: 1076-1082. PMID: 19045975, PMCID: PMC2756150, DOI: 10.1037/a0013679.Peer-Reviewed Original ResearchConceptsSerious adverse eventsAdverse eventsStandard careDrug Abuse Clinical Trials NetworkMore (95% CI 4 to 167 more) serious adverse eventsSAE incidence rateClinical Trials NetworkPsychosocial treatment studiesPsychosocial intervention studiesPercent of participantsPsychosocial trialsIncidence ratePharmaceutical trialsTherapy trialsIntervention studiesTreatment studiesTrials NetworkHuman subjects protection policiesSubstance-abusing participantsContingency managementMotivational enhancementNational InstituteTrialsSignificant differencesCareWhat is usual about “treatment-as-usual”? Data from two multisite effectiveness trials
Santa Ana EJ, Martino S, Ball SA, Nich C, Frankforter TL, Carroll KM. What is usual about “treatment-as-usual”? Data from two multisite effectiveness trials. Journal Of Substance Use And Addiction Treatment 2008, 35: 369-379. PMID: 18337053, PMCID: PMC2712113, DOI: 10.1016/j.jsat.2008.01.003.Peer-Reviewed Original ResearchConceptsEffectiveness trialDrug Abuse Clinical Trials NetworkSubstance useMultisite effectiveness trialClinical Trials NetworkStandard clinical practiceParticipants' substance useCommunity-based drug abuse treatmentDrug abuse treatmentNumber of interventionsSubstance use outcomesPatient outcomesClinical practiceTrials NetworkAbuse treatmentUse outcomesNational InstituteSocial functioningTreatmentTrialsOpen-ended questionsOutcomesStandard practiceEarly stagesEarly sessions
2007
Issues in Designing and Implementing a Spanish‐Language Multi‐Site Clinical Trial
Suarez‐Morales L, Matthews J, Martino S, Ball SA, Rosa C, Farentinos C, Szapocznik J, Carroll KM. Issues in Designing and Implementing a Spanish‐Language Multi‐Site Clinical Trial. American Journal On Addictions 2007, 16: 206-215. PMID: 17612825, PMCID: PMC3628724, DOI: 10.1080/10550490701375707.Peer-Reviewed Original ResearchConceptsClinical trialsMulti-site clinical trialClinical Trials NetworkNIDA Clinical Trials NetworkMotivational enhancement therapySubstance abuse treatmentMulti-site trialClinical staffHealth disparitiesTrials NetworkAbuse treatmentEnhancement therapyTrialsHispanic populationStudy teamAssessment instrumentsDiverse populationsPopulationTherapy
2002
Characteristics, beliefs, and practices of community clinicians trained to provide manual-guided therapy for substance abusers
Ball S, Bachrach K, DeCarlo J, Farentinos C, Keen M, McSherry T, Polcin D, Snead N, Sockriter R, Wrigley P, Zammarelli L, Carroll K. Characteristics, beliefs, and practices of community clinicians trained to provide manual-guided therapy for substance abusers. Journal Of Substance Use And Addiction Treatment 2002, 23: 309-318. PMID: 12495792, DOI: 10.1016/s0740-5472(02)00281-7.Peer-Reviewed Original ResearchConceptsDrug Abuse Clinical Trials NetworkManual-guided therapiesClinical Trials NetworkSample of cliniciansCommunity treatment programsMotivational enhancement therapyCommunity cliniciansCommunity providersTreatment programTrials NetworkTherapyEnhancement therapyCliniciansPrior exposureSubstance abusersMotivational interviewingTreatment manualAddiction therapyRecovery statusCounseling techniquesSuccessful disseminationParticipantsHigh levelsWilling participantsMET meets the real world: design issues and clinical strategies in the Clinical Trials Network
Network F, Carroll K, Farentinos C, Ball S, Crits-Christoph P, Libby B, Morgenstern J, Obert J, Polcin D, Woody G. MET meets the real world: design issues and clinical strategies in the Clinical Trials Network. Journal Of Substance Use And Addiction Treatment 2002, 23: 73-80. PMID: 12220604, PMCID: PMC3651591, DOI: 10.1016/s0740-5472(02)00255-6.Peer-Reviewed Original ResearchConceptsClinical Trials NetworkBrief behavioral treatmentMotivational enhancement therapyDrug abuse treatment programsSubstance abuse treatmentCommunity-based drug abuse treatment programsEnhancement therapyTraining of cliniciansBehavioral treatmentMotivational interviewingTrials NetworkAbuse treatmentCommunity programsTreatment programStudy treatmentRange of studiesClinical trialsClinical strategiesReal worldTrainingStudy sampleTreatmentInterviewingProgramPharmacologic