2018
Culturally Adapted, Web-Based Cognitive Behavioral Therapy for Spanish-Speaking Individuals With Substance Use Disorders: A Randomized Clinical Trial.
Paris M, Silva M, Añez-Nava L, Jaramillo Y, Kiluk BD, Gordon MA, Nich C, Frankforter T, Devore K, Ball SA, Carroll KM. Culturally Adapted, Web-Based Cognitive Behavioral Therapy for Spanish-Speaking Individuals With Substance Use Disorders: A Randomized Clinical Trial. American Journal Of Public Health 2018, 108: 1535-1542. PMID: 30252519, PMCID: PMC6187780, DOI: 10.2105/ajph.2018.304571.Peer-Reviewed Original ResearchConceptsSubstance use disordersCognitive-behavioral treatmentUse disordersSubstance use outcomesClinical trialsWeb-based cognitive behavioral therapyCurrent substance use disorderUse outcomesRandomized clinical trialsStandard outpatient treatmentEvidence-based treatmentsCognitive behavioral therapyPrimary outcomeStandard treatmentOutpatient treatmentStandard outpatientTreatment completionHealth disparitiesBehavioral therapyBehavioral treatmentAddiction treatmentTreatment-seeking individualsGreater reductionTreatmentDisorders
2016
A randomized factorial trial of disulfiram and contingency management to enhance cognitive behavioral therapy for cocaine dependence
Carroll KM, Nich C, Petry NM, Eagan DA, Shi JM, Ball SA. A randomized factorial trial of disulfiram and contingency management to enhance cognitive behavioral therapy for cocaine dependence. Drug And Alcohol Dependence 2016, 160: 135-142. PMID: 26817621, PMCID: PMC4767616, DOI: 10.1016/j.drugalcdep.2015.12.036.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyCocaine outcomesCocaine dependenceCombination of CMDouble-blind clinical trialBehavioral therapyCommunity-based outpatient clinicsUrine sample testingBlind clinical trialSustained treatment effectContingency managementDSM-IV criteriaRandomized factorial trialCurrent cocaine dependenceWeekly individual sessionsCocaine use disorderSecondary outcomesPrimary outcomeYear followOutpatient clinicAddition of disulfiramClinical trialsUse disordersCBT treatmentFactorial trial
2014
Gender differences in clinical outcomes for cocaine dependence: Randomized clinical trials of behavioral therapy and disulfiram
DeVito EE, Babuscio TA, Nich C, Ball SA, Carroll KM. Gender differences in clinical outcomes for cocaine dependence: Randomized clinical trials of behavioral therapy and disulfiram. Drug And Alcohol Dependence 2014, 145: 156-167. PMID: 25457739, PMCID: PMC4268325, DOI: 10.1016/j.drugalcdep.2014.10.007.Peer-Reviewed Original ResearchConceptsRandomized clinical trialsClinical trialsClinical outcomesTreatment outcomesCocaine dependenceBehavioral therapyBehavioral treatment conditionsPoor treatment outcomesEvidence-based treatmentsGender differencesWidespread clinical implementationPoor outcomePharmacological treatmentMedication conditionAddiction pharmacotherapyCocaine useSecondary analysisBehavioral treatmentClinical implementationWomenCareful assessmentDisulfiramOutcomesTrialsMenComputer-Assisted Delivery of Cognitive-Behavioral Therapy: Efficacy and Durability of CBT4CBT Among Cocaine-Dependent Individuals Maintained on Methadone
Carroll KM, Kiluk BD, Nich C, Gordon MA, Portnoy GA, Marino DR, Ball SA. Computer-Assisted Delivery of Cognitive-Behavioral Therapy: Efficacy and Durability of CBT4CBT Among Cocaine-Dependent Individuals Maintained on Methadone. American Journal Of Psychiatry 2014, 171: 436-444. PMID: 24577287, PMCID: PMC4042674, DOI: 10.1176/appi.ajp.2013.13070987.Peer-Reviewed Original ResearchConceptsCocaine-dependent individualsCognitive behavioral therapyMethadone maintenanceCommunity-based outpatient clinicsPrevious pilot trialMethadone maintenance programStandard methadone maintenanceDisseminable strategyDefinitive trialOutpatient clinicClinical trialsEffective adjunctPilot trialTreatment terminationTreatment retentionBetter outcomesConsecutive weeksCBT4CBTWeekly accessAddiction treatmentDurable effectsTrialsSubstance usersStatistical significanceMethadoneToward empirical identification of a clinically meaningful indicator of treatment outcome: Features of candidate indicators and evaluation of sensitivity to treatment effects and relationship to one year follow up cocaine use outcomes
Carroll KM, Kiluk BD, Nich C, DeVito EE, Decker S, LaPaglia D, Duffey D, Babuscio TA, Ball SA. Toward empirical identification of a clinically meaningful indicator of treatment outcome: Features of candidate indicators and evaluation of sensitivity to treatment effects and relationship to one year follow up cocaine use outcomes. Drug And Alcohol Dependence 2014, 137: 3-19. PMID: 24556275, PMCID: PMC4042667, DOI: 10.1016/j.drugalcdep.2014.01.012.Peer-Reviewed Original Research
2013
The Recovery Line: A pilot trial of automated, telephone-based treatment for continued drug use in methadone maintenance
Moore BA, Fazzino T, Barry DT, Fiellin DA, Cutter CJ, Schottenfeld RS, Ball SA. The Recovery Line: A pilot trial of automated, telephone-based treatment for continued drug use in methadone maintenance. Journal Of Substance Use And Addiction Treatment 2013, 45: 63-69. PMID: 23375114, PMCID: PMC3642223, DOI: 10.1016/j.jsat.2012.12.011.Peer-Reviewed Original ResearchMeSH KeywordsAdaptation, PsychologicalAdultAutomationCocaine-Related DisordersFeasibility StudiesFemaleHumansMaleMethadoneMiddle AgedOpiate Substitution TreatmentOpioid-Related DisordersPatient Acceptance of Health CarePatient SatisfactionPilot ProjectsSubstance Abuse DetectionTelephoneTherapy, Computer-AssistedConceptsMethadone maintenanceLarge clinical trialsTelephone-based treatmentCurrent pilot studyPatient satisfactionClinical trialsPatient utilizationComputer-based treatmentPilot trialInitial efficacyInteractive voice response systemDrug usePatientsScreen outcomesVoice response systemPilot studyIllicit drugsTreatmentDaily useTrialsEfficacyOpioidsAbstinenceRecovery lineCocaine
2011
Mutual influence in therapist competence and adherence to motivational enhancement therapy
Imel ZE, Baer JS, Martino S, Ball SA, Carroll KM. Mutual influence in therapist competence and adherence to motivational enhancement therapy. Drug And Alcohol Dependence 2011, 115: 229-236. PMID: 21227601, PMCID: PMC3397170, DOI: 10.1016/j.drugalcdep.2010.11.010.Peer-Reviewed Original ResearchMeSH KeywordsBehavior, AddictiveClinical CompetenceCounselingFemaleHealth PersonnelHumansMaleMotivationMulticenter Studies as TopicPatient Acceptance of Health CarePatient ComplianceProfessional CompetenceProfessional-Patient RelationsPsychotherapyRandomized Controlled Trials as TopicSeverity of Illness IndexTreatment OutcomeConceptsMotivational enhancement therapyClinical trialsTherapist adherenceEnhancement therapyMulti-site clinical trialLarge multi-site clinical trialDays of useTreatment protocolTherapists' caseloadsAdherenceTherapist competenceTrialsTherapist performanceClient severityTherapyCaseloadTherapistsThree-level multilevel models
2010
Cognitive Function and Treatment Response in a Randomized Clinical Trial of Computer-Based Training in Cognitive-Behavioral Therapy
Carroll KM, Kiluk BD, Nich C, Babuscio TA, Brewer JA, Potenza MN, Ball SA, Martino S, Rounsaville BJ, Lejuez CW. Cognitive Function and Treatment Response in a Randomized Clinical Trial of Computer-Based Training in Cognitive-Behavioral Therapy. Substance Use & Misuse 2010, 46: 23-34. PMID: 21190403, PMCID: PMC3083447, DOI: 10.3109/10826084.2011.521069.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyCognitive functionComputer-assisted cognitive behavioral therapyComputer-assisted versionCognitive demandsCognitive functioningRisk takingPoor substanceSubstance usersHomework assignmentsHigh levelsClinical trialsSecondary analysisFunctioningRandomized clinical trialsParticipantsTreatment responseTakingTrainingSessionsSuch patientsMultisite effectiveness trials of treatments for substance abuse and co-occurring problems: Have we chosen the best designs?
Nunes EV, Ball S, Booth R, Brigham G, Calsyn DA, Carroll K, Feaster DJ, Hien D, Hubbard RL, Ling W, Petry NM, Rotrosen J, Selzer J, Stitzer M, Tross S, Wakim P, Winhusen T, Woody G. Multisite effectiveness trials of treatments for substance abuse and co-occurring problems: Have we chosen the best designs? Journal Of Substance Use And Addiction Treatment 2010, 38: s97-s112. PMID: 20307801, PMCID: PMC2909698, DOI: 10.1016/j.jsat.2010.01.012.Peer-Reviewed Original ResearchMeSH KeywordsCommunity Health ServicesComparative Effectiveness ResearchEvidence-Based MedicineHumansInformation DisseminationNational Institute on Drug Abuse (U.S.)Randomized Controlled Trials as TopicResearch DesignSubstance Abuse Treatment CentersSubstance-Related DisordersTreatment OutcomeUnited StatesConceptsClinical Trials NetworkMultisite effectiveness trialEffectiveness trialNational Drug Abuse Treatment Clinical Trials NetworkSubstance abuseNew interventionsReal-world clinical settingNew treatment interventionsPrimary outcome paperFuture effectiveness trialHIV risk behaviorsEvidence-based treatmentsBehavioral health problemsCo-occurring problemsOutcome papersClinical trialsHIV riskTreatment interventionsHealth problemsRisk behaviorsClinical settingTrials NetworkDrug abuseTrialsSuch treatment
2009
A Multisite Randomized Effectiveness Trial of Motivational Enhancement Therapy for Spanish-Speaking Substance Users
Carroll KM, Martino S, Ball SA, Nich C, Frankforter T, Anez LM, Paris M, Suarez-Morales L, Szapocznik J, Miller WR, Rosa C, Matthews J, Farentinos C. A Multisite Randomized Effectiveness Trial of Motivational Enhancement Therapy for Spanish-Speaking Substance Users. Journal Of Consulting And Clinical Psychology 2009, 77: 993-999. PMID: 19803579, PMCID: PMC2792592, DOI: 10.1037/a0016489.Peer-Reviewed Original ResearchConceptsMotivational enhancement therapyEnhancement therapySubstance useSubstance usersRandomized Effectiveness TrialIndividual sessionsCurrent substance useX time interactionTreatment condition interactionCondition x time interactionSubstance use problemsClinical trialsEffectiveness trialTreatment exposureTherapy phaseTreatment retentionTreatment sessionsHispanic adultsTherapyHeterogeneous groupHispanic individualsTime interactionIndividual treatmentTrialsUse problemsA treatment for substance abusing pregnant women
Yonkers KA, Howell HB, Allen AE, Ball SA, Pantalon MV, Rounsaville BJ. A treatment for substance abusing pregnant women. Archives Of Women's Mental Health 2009, 12: 221. PMID: 19350369, PMCID: PMC3103065, DOI: 10.1007/s00737-009-0069-2.Peer-Reviewed Original ResearchConceptsPregnant womenMaternal Health ClinicRoutine prenatal careManualized behavioral treatmentYale AdherencePrenatal careClinical trialsHealth clinicsHealth cliniciansBreath testBehavioral treatmentPilot studySubstance useMotivational interviewingSmall urban cityTreatment fidelityTreatment deliveryWomenTherapyCognitive therapyTreatmentSelf-ReportNew HavenClinicCliniciansConstruct, concurrent and predictive validity of the URICA: Data from two multi-site clinical trials
Field CA, Adinoff B, Harris TR, Ball SA, Carroll KM. Construct, concurrent and predictive validity of the URICA: Data from two multi-site clinical trials. Drug And Alcohol Dependence 2009, 101: 115-123. PMID: 19157723, PMCID: PMC3097110, DOI: 10.1016/j.drugalcdep.2008.12.003.Peer-Reviewed Original ResearchConceptsPredictive validityCommitted actionRhode Island Change AssessmentRole of motivationEffect of motivationBrief motivational interventionMotivational enhancement therapyComposite scoreTreatment outcomesConfirmatory factor analysisAlcohol dependenceDrug Abuse Clinical Trials NetworkClinical trialsMotivational interventionEnhancement therapyMotivational interviewingAlcohol-dependent patientsFactor structureAddiction severityMulti-site clinical trialSubstance useClinical Trials NetworkConstruct validityTreatment retentionURICA
2008
Enduring effects of a computer-assisted training program for cognitive behavioral therapy: A 6-month follow-up of CBT4CBT
Carroll KM, Ball SA, Martino S, Nich C, Babuscio TA, Rounsaville BJ. Enduring effects of a computer-assisted training program for cognitive behavioral therapy: A 6-month follow-up of CBT4CBT. Drug And Alcohol Dependence 2008, 100: 178-181. PMID: 19041197, PMCID: PMC2742309, DOI: 10.1016/j.drugalcdep.2008.09.015.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyBehavioral therapyComputer-assisted training programSubstance dependenceComputer-based trainingSubstance use outcomesComputer-assisted versionDrug useEnduring effectCBT4CBTUse outcomesRandomized clinical trialsTreatment retentionDurability of effectTraining programOutpatient communityStudy treatmentStandard treatmentOutpatient treatmentClinical trialsTreatment conditionsParticipantsSignificant differencesTreatmentRegression analysisComputer-Assisted Delivery of Cognitive-Behavioral Therapy for Addiction: A Randomized Trial of CBT4CBT
Carroll KM, Ball SA, Martino S, Nich C, Babuscio TA, Nuro KF, Gordon MA, Portnoy GA, Rounsaville BJ. Computer-Assisted Delivery of Cognitive-Behavioral Therapy for Addiction: A Randomized Trial of CBT4CBT. American Journal Of Psychiatry 2008, 165: 881-888. PMID: 18450927, PMCID: PMC2562873, DOI: 10.1176/appi.ajp.2008.07111835.Peer-Reviewed Original Research
2007
Site Matters: Multisite Randomized Trial of Motivational Enhancement Therapy in Community Drug Abuse Clinics
Ball SA, Martino S, Nich C, Frankforter TL, Van Horn D, Crits-Christoph P, Woody GE, Obert JL, Farentinos C, Carroll KM. Site Matters: Multisite Randomized Trial of Motivational Enhancement Therapy in Community Drug Abuse Clinics. Journal Of Consulting And Clinical Psychology 2007, 75: 556-567. PMID: 17663610, PMCID: PMC2148493, DOI: 10.1037/0022-006x.75.4.556.Peer-Reviewed Original ResearchConceptsMotivational enhancement therapySubstance useEnhancement therapyBrief intervention conditionsOutpatient substance abuse programsSubstance use reductionDrug abuse clinicsSubstance abuse programsSession audiotapesRandomized trialsClinical trialsMultisite Randomized TrialSustained reductionTherapy phaseDrug usersPrimary alcohol usersAlcohol usersAbuse programsIntervention conditionSignificant increaseTherapyTrialsCAUOutpatientsClinicIssues in Designing and Implementing a Spanish‐Language Multi‐Site Clinical Trial
Suarez‐Morales L, Matthews J, Martino S, Ball SA, Rosa C, Farentinos C, Szapocznik J, Carroll KM. Issues in Designing and Implementing a Spanish‐Language Multi‐Site Clinical Trial. American Journal On Addictions 2007, 16: 206-215. PMID: 17612825, PMCID: PMC3628724, DOI: 10.1080/10550490701375707.Peer-Reviewed Original ResearchConceptsClinical trialsMulti-site clinical trialClinical Trials NetworkNIDA Clinical Trials NetworkMotivational enhancement therapySubstance abuse treatmentMulti-site trialClinical staffHealth disparitiesTrials NetworkAbuse treatmentEnhancement therapyTrialsHispanic populationStudy teamAssessment instrumentsDiverse populationsPopulationTherapy
2005
Motivational interviewing to improve treatment engagement and outcome in individuals seeking treatment for substance abuse: A multisite effectiveness study
Carroll KM, Ball SA, Nich C, Martino S, Frankforter TL, Farentinos C, Kunkel LE, Mikulich-Gilbertson SK, Morgenstern J, Obert JL, Polcin D, Snead N, Woody GE, Network F. Motivational interviewing to improve treatment engagement and outcome in individuals seeking treatment for substance abuse: A multisite effectiveness study. Drug And Alcohol Dependence 2005, 81: 301-312. PMID: 16169159, PMCID: PMC2386852, DOI: 10.1016/j.drugalcdep.2005.08.002.Peer-Reviewed Original ResearchConceptsClinical practiceCommunity-based treatment settingsCourse of treatmentStandard clinical practiceCommunity-based cliniciansForm of treatmentMultisite effectiveness studyMI techniquesMotivational interviewing techniquesSubstance use outcomesSession audiotapesEvaluation sessionsOutpatient treatmentClinical trialsImproved outcomesStandard interventionTreatment settingsTreatment engagementBehavioral therapyEffectiveness studiesSubstance abuseSame sessionUse outcomesHigher skill ratingsSubstance usersSubstance abuse and personality disorders in homeless drop-in center clients: symptom severity and psychotherapy retention in a randomized clinical trial
Ball SA, Cobb-Richardson P, Connolly AJ, Bujosa CT, O'Neall TW. Substance abuse and personality disorders in homeless drop-in center clients: symptom severity and psychotherapy retention in a randomized clinical trial. Comprehensive Psychiatry 2005, 46: 371-379. PMID: 16122538, DOI: 10.1016/j.comppsych.2004.11.003.Peer-Reviewed Original ResearchMeSH KeywordsAdaptation, PsychologicalAdultAmbulatory CareCrimeFemaleHumansIll-Housed PersonsInterpersonal RelationsMaleMass ScreeningMiddle AgedPersonality DisordersPsychologyPsychotherapyRetention, PsychologySeverity of Illness IndexSocial BehaviorSubstance-Related DisordersSurveys and QuestionnairesConceptsPsychiatric symptomsPersonality disorderPsychosocial impairmentSubstance abuse relapse preventionHomeless dropSignificant psychiatric symptomsRandomized clinical trialsCluster B personality disordersMental health servicesB personality disordersTherapy retentionPrimary outcomePersonality disorder symptomsSubstance abuse counselingClinical trialsTreatment responsePsychotherapy retentionHealth servicesRelapse preventionPsychosocial problemsSymptom severitySubstance abuseSymptomsSubstance abusersC disorders
2004
Millon Clinical Multiaxial Inventory-III Subtypes of Opioid Dependence: Validity and Matching to Behavioral Therapies
Ball SA, Nich C, Rounsaville BJ, Eagan D, Carroll KM. Millon Clinical Multiaxial Inventory-III Subtypes of Opioid Dependence: Validity and Matching to Behavioral Therapies. Journal Of Consulting And Clinical Psychology 2004, 72: 698-711. PMID: 15301655, PMCID: PMC3709250, DOI: 10.1037/0022-006x.72.4.698.Peer-Reviewed Original ResearchConceptsLess symptom improvementOpioid-dependent outpatientsOpioid dependenceSymptom improvementClinical trialsBetter outcomesPredictive validity analysesBehavioral therapyVoucher conditionSubtypesAffective disturbancesIntervention conditionMatching AnalysisPredictive validityCounselingValidity analysisNaltrexoneGroup counselingOutpatientsTherapyTrials
2002
MET meets the real world: design issues and clinical strategies in the Clinical Trials Network
Network F, Carroll K, Farentinos C, Ball S, Crits-Christoph P, Libby B, Morgenstern J, Obert J, Polcin D, Woody G. MET meets the real world: design issues and clinical strategies in the Clinical Trials Network. Journal Of Substance Use And Addiction Treatment 2002, 23: 73-80. PMID: 12220604, PMCID: PMC3651591, DOI: 10.1016/s0740-5472(02)00255-6.Peer-Reviewed Original ResearchConceptsClinical Trials NetworkBrief behavioral treatmentMotivational enhancement therapyDrug abuse treatment programsSubstance abuse treatmentCommunity-based drug abuse treatment programsEnhancement therapyTraining of cliniciansBehavioral treatmentMotivational interviewingTrials NetworkAbuse treatmentCommunity programsTreatment programStudy treatmentRange of studiesClinical trialsClinical strategiesReal worldTrainingStudy sampleTreatmentInterviewingProgramPharmacologic