2013
Variable Selection and Prediction Using a Nested, Matched Case-Control Study: Application to Hospital Acquired Pneumonia in Stroke Patients
Qian J, Payabvash S, Kemmling A, Lev MH, Schwamm LH, Betensky RA. Variable Selection and Prediction Using a Nested, Matched Case-Control Study: Application to Hospital Acquired Pneumonia in Stroke Patients. Biometrics 2013, 70: 153-163. PMID: 24320930, PMCID: PMC3954429, DOI: 10.1111/biom.12113.Peer-Reviewed Original ResearchConceptsMassachusetts General HospitalCase-control studyStroke patientsAcute ischemic stroke patientsBrain regionsMatched Case-Control StudyHospital-Acquired PneumoniaIschemic stroke patientsLarge prospective studiesUnconditional logistic regressionCase-control designSpecific brain regionsAcquired PneumoniaAcute infarctionClinical featuresProspective studyClinical variablesGeneral HospitalEpidemiologic studiesPatientsModern imagingLarger studyLogistic regressionAppropriate statistical analysisHAP studies
2012
Malignant CTA Collateral Profile Is Highly Specific for Large Admission DWI Infarct Core and Poor Outcome in Acute Stroke
Souza LC, Yoo AJ, Chaudhry ZA, Payabvash S, Kemmling A, Schaefer PW, Hirsch JA, Furie KL, González RG, Nogueira RG, Lev MH. Malignant CTA Collateral Profile Is Highly Specific for Large Admission DWI Infarct Core and Poor Outcome in Acute Stroke. American Journal Of Neuroradiology 2012, 33: 1331-1336. PMID: 22383238, PMCID: PMC3888794, DOI: 10.3174/ajnr.a2985.Peer-Reviewed Original ResearchConceptsDWI lesion volumeLesion volumeDWI volumeNIHSS scorePoor outcomeHigher median NIHSS scoresROC analysisDWI lesion sizeLarger DWI volumeMedian NIHSS scoreAcute stroke treatmentAdmission NIHSS scoreOnly independent predictorPoor functional outcomeIntracranial ICA occlusionCTA collateralsAcute strokeICA occlusionProximal occlusionIndependent predictorsStroke treatmentInfarct sizeClinical variablesFunctional outcomeInfarct core