2018
Distinctive features of gastrointestinal stromal tumors arising from the colon and rectum
Zhu R, Liu F, Grisotti G, Pérez-Irizarry J, Cha CH, Johnson CH, Boffa DJ, Han D, Johung KL, Zhang Y, Khan SA. Distinctive features of gastrointestinal stromal tumors arising from the colon and rectum. Journal Of Gastrointestinal Oncology 2018, 9: 231-240. PMID: 29755761, PMCID: PMC5934147, DOI: 10.21037/jgo.2017.11.12.Peer-Reviewed Original ResearchRectal gastrointestinal stromal tumorGastric gastrointestinal stromal tumorsGastrointestinal stromal tumorsNational Cancer Data BaseAdjuvant therapyOverall survivalSystemic therapyStromal tumorsCases of GISTColonic gastrointestinal stromal tumorsSmall bowel originAdjuvant systemic therapyWorse overall survivalUnique clinicopathologic featuresBowel originTherapy prolongsClinical characteristicsPatient demographicsLocal excisionPrognostic factorsPropensity matchingSurgical treatmentTreatment guidelinesClinicopathologic featuresClinical care
2012
Tumor Endothelial Inflammation Predicts Clinical Outcome in Diverse Human Cancers
Pitroda SP, Zhou T, Sweis RF, Filippo M, Labay E, Beckett MA, Mauceri HJ, Liang H, Darga TE, Perakis S, Khan SA, Sutton HG, Zhang W, Khodarev NN, Garcia JG, Weichselbaum RR. Tumor Endothelial Inflammation Predicts Clinical Outcome in Diverse Human Cancers. PLOS ONE 2012, 7: e46104. PMID: 23056240, PMCID: PMC3464251, DOI: 10.1371/journal.pone.0046104.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAnimalsBreast NeoplasmsCell Line, TumorCells, CulturedColonic NeoplasmsEndothelial CellsEndothelium, VascularFemaleGene Expression ProfilingGliomaHuman Umbilical Vein Endothelial CellsHumansInflammationKaplan-Meier EstimateLung NeoplasmsMaleMiceMiddle AgedMultivariate AnalysisNeoplasmsNeovascularization, PathologicOligonucleotide Array Sequence AnalysisTumor Necrosis Factor-alphaConceptsEndothelial inflammationEndothelial cellsOverall survivalHuman cancersDiverse human cancersExperimental modelTumor-associated endothelial cellsStromal inflammatory responsePathological prognostic factorsEndothelial-derived factorsPro-inflammatory cytokinesInflammatory gene expressionPathologic tissue specimensUntreated endothelial cellsVascular endothelial cellsMultiple human cancersInflammatory signatureHuman endothelial cellsPrognostic factorsClinical outcomesChronic inflammationInflammatory pathwaysLung cancerTumor necrosisInflammatory response