2017
Prognostic signatures of oligometastasis in colorectal cancer liver metastasis.
Khan S, Paty P, Zeng Z, Lu J. Prognostic signatures of oligometastasis in colorectal cancer liver metastasis. Journal Of Clinical Oncology 2017, 35: 3588-3588. DOI: 10.1200/jco.2017.35.15_suppl.3588.Peer-Reviewed Original ResearchColorectal cancer liver metastasesCancer liver metastasesHox gene familyLiver metastasesGene familyLonger recurrence-free survivalUnique molecular subtypePrimary colorectal cancerRecurrence-free survivalSelection of patientsRisk of recurrenceUseful prognostic informationFrozen tumor tissueCRCLM patientsOligometastatic phenotypeMetastasis resectionFree survivalLimited metastasesLiver resectionOverall survivalClinical outcomesWidespread metastasesFurther mechanistic studiesColorectal cancerHOX family members
2008
c-Met gene amplification is associated with advanced stage colorectal cancer and liver metastases
Zeng ZS, Weiser MR, Kuntz E, Chen CT, Khan SA, Forslund A, Nash GM, Gimbel M, Yamaguchi Y, Culliford AT, D’Alessio M, Barany F, Paty PB. c-Met gene amplification is associated with advanced stage colorectal cancer and liver metastases. Cancer Letters 2008, 265: 258-269. PMID: 18395971, PMCID: PMC4367187, DOI: 10.1016/j.canlet.2008.02.049.Peer-Reviewed Original ResearchConceptsC-MET gene amplificationC-Met gene copy numberLiver metastasesPrimary colorectal cancerColorectal cancerGene amplificationC-MetAdvanced stage colorectal cancerAdvanced colorectal cancerStage colorectal cancerNormal colonic mucosaLiver resectionTyrosine kinaseGene copy numberDistant metastasisPrimary cancerLung cancerColonic mucosaGastric cancerNormal mucosaMetastasisNormal liverTumor growthMetastatic progressionLiver tissue