2020
DNA aptamer-based non-faradaic impedance biosensor for detecting E. coli
Abdelrasoul GN, Anwar A, MacKay S, Tamura M, Shah MA, Khasa DP, Montgomery RR, Ko AI, Chen J. DNA aptamer-based non-faradaic impedance biosensor for detecting E. coli. Analytica Chimica Acta 2020, 1107: 135-144. PMID: 32200887, DOI: 10.1016/j.aca.2020.02.004.Peer-Reviewed Original ResearchConceptsField-emission scanning electron microscopyImpedance-based biosensorAtomic force microscopySelf-assembled monolayersInterdigitated ElectrodesIDE surfaceSubstrate materialEmission scanning electron microscopyMolecular recognition elementsEnzyme-linked immunosorbent assayConventional detection approachesScanning electron microscopyIDE arrayImpedance biosensorLimit of detectionForce microscopyBiosensorSurface chemistryAptamerPolymerase chain reaction assaysRecognition elementThiol mixturesElectron microscopyEnvironmental monitoringChain reaction assays
2018
Non-invasive Point-of-Care Device To Diagnose Acute Mesenteric Ischemia
Abdelrasoul GN, MacKay S, Salim S, Ismond K, Tamura M, Khalifa C, Mannan E, Lin D, Mandal T, Montgomery R, Wishart D, Chen J, Khadaroo R. Non-invasive Point-of-Care Device To Diagnose Acute Mesenteric Ischemia. ACS Sensors 2018, 3: 2296-2302. PMID: 30335977, DOI: 10.1021/acssensors.8b00558.Peer-Reviewed Original ResearchConceptsGold nanoparticlesBiosensor devicesNon-faradic impedance spectroscopyElectrochemical biosensor deviceNon-invasive pointElectrochemical biosensorDetection antibodyCapture antibodyCare devicesImmediate bedside diagnosisElectrode surfacePhotolithographic techniquesDetection signalSandwich mannerImpedance spectroscopySilicon dioxideBedside translationImpedance signalDevicesTarget proteinsI-FABP concentrationsFatty acid binding proteinNanoparticlesBiosensorSpectroscopy