1991
Localization of Basic Fibroblast Growth Factor mRNA in Melanocytic Lesions by In Situ Hybridization
Scott G, Stoler M, Sarkar S, Halaban R. Localization of Basic Fibroblast Growth Factor mRNA in Melanocytic Lesions by In Situ Hybridization. Journal Of Investigative Dermatology 1991, 96: 318-322. PMID: 2002252, DOI: 10.1111/1523-1747.ep12465203.Peer-Reviewed Original ResearchConceptsBFGF gene transcriptsBasic fibroblast growth factorGene transcriptsCell populationsGrowth factorNormal human melanocytesDermal cell typesFibroblast growth factorHuman melanocytesCell typesParacrine growth factorCellular proliferationAberrant expressionSitu hybridizationMelanocytic lesionsMetastatic melanomaBasic FGF expressionFGF expressionGrowth independenceTranscriptsBasic fibroblast growth factor mRNADysplastic neviExpressionParacrine mechanismsMelanocytes
1988
Paracrine Stimulation of Melanocytes by Keratinocytes through Basic Fibroblast Growth Factora
HALABAN R, LANGDON R, BIRCHALL N, CCUONO C, BAIRD A, SCOTT G, MOELLOMANN G, MCGUIRE J. Paracrine Stimulation of Melanocytes by Keratinocytes through Basic Fibroblast Growth Factora. Annals Of The New York Academy Of Sciences 1988, 548: 180-190. PMID: 2470294, DOI: 10.1111/j.1749-6632.1988.tb18805.x.Peer-Reviewed Original ResearchConceptsBasic fibroblast growth factorBFGF gene transcriptsGrowth factorNormal human melanocytesGene transcriptsFibroblast growth factorNatural growth factorsNorthern blotHuman melanocytesMelanocyte mitogensMelanocyte growthParacrine stimulationMelanocytesHuman keratinocytesSynthetic peptidesKeratinocytesUltraviolet BTranscriptsPresence of keratinocytesMitogenBindingBlotProliferationMonophosphateBasic fibroblast growth factor from human keratinocytes is a natural mitogen for melanocytes.
Halaban R, Langdon R, Birchall N, Cuono C, Baird A, Scott G, Moellmann G, McGuire J. Basic fibroblast growth factor from human keratinocytes is a natural mitogen for melanocytes. Journal Of Cell Biology 1988, 107: 1611-1619. PMID: 2459134, PMCID: PMC2115244, DOI: 10.1083/jcb.107.4.1611.Peer-Reviewed Original ResearchConceptsBasic fibroblast growth factorFibroblast growth factorBFGF gene transcriptsHuman melanocytesGrowth factorNormal human melanocytesNatural mitogenHuman keratinocytesGene transcriptsNatural growth factorsNorthern blotMelanocyte mitogensMelanocyte growthMelanocytesPure culturePresence of serumMitogenSynthetic peptidesKeratinocytesCellsCAMPTranscriptsPresence of keratinocytesBindingBlotbFGF as an autocrine growth factor for human melanomas.
Halaban R, Kwon BS, Ghosh S, Delli Bovi P, Baird A. bFGF as an autocrine growth factor for human melanomas. Oncogene Research 1988, 3: 177-86. PMID: 3226725.Peer-Reviewed Original ResearchConceptsBasic fibroblast growth factorNormal human melanocytesBFGF gene transcriptsHuman melanocytesGrowth factorAutocrine growth factorGene transcriptsHuman metastatic melanomaMolecular mechanismsFibroblast growth factorNormal melanocytesCyclic adenosine monophosphateSerum-containing mediumAnti-bFGF antibodyMelanoma cellsAbnormal expressionAdenosine monophosphateHuman melanomaMelanocytesRegular culture mediumDibutyryl cyclic adenosine monophosphateMitogenic activityCulture mediumCellsTranscripts