2021
364 KRAS mutations in patients with nonsquamous non–small-cell lung cancer: prevalence and relationship with PD-L1 expression, tumor mutation burden and smoking status
Garassino M, Rodriguez-Abreu D, Gadgeel S, Kowalski D, Kasahara K, Felip E, Wu Y, de Castro G, Cho B, Turna H, Horinouchi H, Reck M, Hui R, Garon E, Boyer M, Mok T, Lopes G, Kobie J, Li Y, Ayers M, Cristescu R, Zhao B, Pietanza M, Herbst R. 364 KRAS mutations in patients with nonsquamous non–small-cell lung cancer: prevalence and relationship with PD-L1 expression, tumor mutation burden and smoking status. Journal For ImmunoTherapy Of Cancer 2021, 9: a391-a391. DOI: 10.1136/jitc-2021-sitc2021.364.Peer-Reviewed Original ResearchPD-L1 TPSKRAS G12C mutationPD-L1 expressionPlatinum-based chemotherapyTumor PD-L1 expressionEGFR/ALK alterationsFirst-line therapyNon-squamous NSCLCNonsquamous NSCLCTumor mutation burdenPembrolizumab monotherapyKRAS mutational statusKEYNOTE-042KEYNOTE-189KRAS mutationsFormer smokersG12C mutationPatient characteristicsALK alterationsPD-L1Smoking statusMutation burdenKRAS G12CHigh tumor PD-L1 expressionMutational status
2015
Electronic Nicotine Delivery Systems: A Policy Statement from the American Association for Cancer Research and the American Society of Clinical Oncology
Brandon TH, Goniewicz ML, Hanna NH, Hatsukami DK, Herbst RS, Hobin JA, Ostroff JS, Shields PG, Toll BA, Tyne CA, Viswanath K, Warren GW. Electronic Nicotine Delivery Systems: A Policy Statement from the American Association for Cancer Research and the American Society of Clinical Oncology. Clinical Cancer Research 2015, 21: 514-525. PMID: 25573384, DOI: 10.1158/1078-0432.ccr-14-2544.Peer-Reviewed Original ResearchConceptsElectronic nicotine delivery systemsTobacco useClinical OncologyHarm-reduction devicesNumber one preventable causeAmerican SocietyCombustible tobacco productsNicotine delivery systemsCancer researchCombustible tobacco useAdverse health effectsAmerican AssociationChildproof capsFormer smokersCigarette smokingPreventable causeSmoking ratesENDS useDefinitive dataE-cigarettesTobacco productsHealth effectsSmokersSmokingHealth impactsElectronic Nicotine Delivery Systems: A Policy Statement From the American Association for Cancer Research and the American Society of Clinical Oncology
Brandon TH, Goniewicz ML, Hanna NH, Hatsukami DK, Herbst RS, Hobin JA, Ostroff JS, Shields PG, Toll BA, Tyne CA, Viswanath K, Warren GW. Electronic Nicotine Delivery Systems: A Policy Statement From the American Association for Cancer Research and the American Society of Clinical Oncology. Journal Of Clinical Oncology 2015, 33: 952-963. PMID: 25572671, DOI: 10.1200/jco.2014.59.4465.Peer-Reviewed Original ResearchConceptsElectronic nicotine delivery systemsClinical OncologyTobacco useAmerican SocietyCancer researchHarm-reduction devicesNumber one preventable causeAmerican AssociationJoint writing groupCombustible tobacco productsClinical cancer researchNicotine delivery systemsCombustible tobacco useAdverse health effectsChildproof capsFormer smokersCigarette smokingPreventable causeTobacco cessationSmoking ratesUS FoodDrug AdministrationENDS useDefinitive dataElectronic cigarettes