2018
60 How to Promote and Organize Clinical Research in Lung Cancer
Barlesi F, Mazieres J, Zhou Y, Herbst R, Zalcman G. 60 How to Promote and Organize Clinical Research in Lung Cancer. 2018, 628-634.e2. DOI: 10.1016/b978-0-323-52357-8.00060-3.Peer-Reviewed Original ResearchLung cancerClinical trialsNew clinical trial designsClinical trial designPotential therapeutic drugBasic science dataClinical researchersAppropriate trialsPreclinical dataPreventative optionsCertain therapiesTrial designNew treatmentsClinical researchPreclinical conceptsTherapeutic drugsCancerTrialsPatientsPersonalized medicineTherapyBiomarkers
2009
Integration of Molecular Profiling into the Lung Cancer Clinic
Pao W, Kris MG, Iafrate AJ, Ladanyi M, Jänne PA, Wistuba II, Miake-Lye R, Herbst RS, Carbone DP, Johnson BE, Lynch TJ. Integration of Molecular Profiling into the Lung Cancer Clinic. Clinical Cancer Research 2009, 15: 5317-5322. PMID: 19706816, DOI: 10.1158/1078-0432.ccr-09-0913.Peer-Reviewed Original ResearchConceptsMolecular profilingLung cancer clinicThoracic oncology centersMore effective treatmentsMedical oncologyOncology centersAppropriate trialsLung cancerOncology practiceCancer clinicEffective treatmentSide effectsMolecular aberrationsNecessary end pointEnd pointPatientsRoutine partTherapyAppropriate candidatesTrialsRare mutationsAdequate numberStandardized methodMultiple institutionsEarly stages