Synthesis and properties of adenosine oligonucleotide analogues containing methylene groups in place of phosphodiester 5'-oxygens.
Breaker R, Gough G, Gilham P. Synthesis and properties of adenosine oligonucleotide analogues containing methylene groups in place of phosphodiester 5'-oxygens. Biochemistry 1993, 32: 9125-8. PMID: 8396423, DOI: 10.1021/bi00086a017.Peer-Reviewed Original ResearchConceptsMethylene groupInitial productAlkali yieldsForm AAnaloguesPhosphatePolynucleotide phosphorylaseMn2Inorganic phosphateMg2YieldProducts