1990
Capsaicin-sensitive primary sensory neurons are potent modulators of murine delayed-type hypersensitivity reactions.
Girolomoni G, Tigelaar R. Capsaicin-sensitive primary sensory neurons are potent modulators of murine delayed-type hypersensitivity reactions. The Journal Of Immunology 1990, 145: 1105-12. PMID: 2380551, DOI: 10.4049/jimmunol.145.4.1105.Peer-Reviewed Original ResearchConceptsDelayed-type hypersensitivity reactionPrimary sensory neuronsHypersensitivity reactionsSensory neuronsCapsaicin-sensitive primary sensory neuronsBALB/c miceCapsaicin-pretreated miceEffector T cellsContact sensitivity reactionAdoptive transfer experimentsCutaneous inflammatory reactionsTopical capsaicinCapsaicin pretreatmentNeurogenic inflammationC miceNeuropeptide releaseHistologic studyInflammatory reactionT cellsPeptidergic neuronsIrritant reactionsSensitivity reactionsSuch neuronsCapsaicinPotent modulator
1988
Thy-1+ epidermal cells in nude mice are distinct from their counterparts in thymus-bearing mice. A study of morphology, function, and T cell receptor expression.
Nixon-Fulton J, Kuziel W, Santerse B, Bergstresser P, Tucker P, Tigelaar R. Thy-1+ epidermal cells in nude mice are distinct from their counterparts in thymus-bearing mice. A study of morphology, function, and T cell receptor expression. The Journal Of Immunology 1988, 141: 1897-903. PMID: 2902136, DOI: 10.4049/jimmunol.141.6.1897.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntigens, SurfaceBlotting, NorthernBlotting, SouthernCell DivisionConcanavalin ADendritic CellsEpidermal CellsEpidermisEthersFemaleInterleukin-2IonomycinMaleMiceMice, Inbred BALB CMice, Inbred CBAMice, NudeReceptors, Antigen, T-CellSpecies SpecificityTetradecanoylphorbol AcetateThy-1 AntigensThymus GlandConceptsIL-2Thy-1Nude miceNormal miceLow-dose IL-2BALB/c miceT cell receptor expressionModest proliferative responseThymus-bearing miceCell receptor expressionT cell differentiationTCR-gamma transcriptsC miceReceptor expressionAthymic miceProliferative responseNormal animalsTCR mRNACalcium ionophoreEpidermal cellsMiceNormal CBACon AFollicular epitheliumPopulation of cells
1973
Graft-vs-host reactivity of mouse thymocytes: effect of cortisone pretreatment of donors.
Tigelaar R, Asofsky R. Graft-vs-host reactivity of mouse thymocytes: effect of cortisone pretreatment of donors. The Journal Of Immunology 1973, 110: 567-74. PMID: 4405321, DOI: 10.4049/jimmunol.110.2.567.Peer-Reviewed Original ResearchConceptsSpleen weightNormal thymocytesPeripheral lymph node cellsCell-mediated immune reactionsBALB/c miceLymph node cellsThymus-derived cellsCortisone-resistant thymocytesLymphoid cell populationsCortisone pretreatmentGVH reactivityHost reactivityC miceNode cellsNormal donorsImmune reactionsThymus cellsCortisone acetateCumulative mortalityThymocytesMortalityUnique populationCell populationsMouse thymocytesDistinct cell types