2024
Opioid Dose Variation in Cardiac Surgery: A Multicenter Study of Practice.
Fisher C, Janda A, Zhao X, Deng Y, Bardia A, Yanez N, Burns M, Aziz M, Treggiari M, Mathis M, Lin H, Schonberger R. Opioid Dose Variation in Cardiac Surgery: A Multicenter Study of Practice. Anesthesia & Analgesia 2024 PMID: 39167548, DOI: 10.1213/ane.0000000000007128.Peer-Reviewed Original ResearchCardiac surgeryOpioid doseDose variationIntraoperative opioid administrationIntraoperative opioid doseHigh-dose opioidsAdult cardiac surgerySurgical differencesOpioid-freeOpioid administrationOpioid useMultimodal analgesiaAnalgesic techniquesCardiopulmonary bypassMulticenter studyFentanyl equivalentsSufentanil infusionSurgical patientsOpioidSurgeryAnesthetic techniqueCardiac casesAttending anesthesiologistPatientsDose
2023
Patient-, Clinician-, and Institution-level Variation in Inotrope Use for Cardiac Surgery: A Multicenter Observational Analysis
Mathis M, Janda A, Kheterpal S, Schonberger R, Pagani F, Engoren M, Mentz G, Shook D, Muehlschlegel J, Cassidy R, Clark D, Colquhoun D, Freundlich R, Jewell E. Patient-, Clinician-, and Institution-level Variation in Inotrope Use for Cardiac Surgery: A Multicenter Observational Analysis. Anesthesiology 2023, 139: 122-141. PMID: 37094103, PMCID: PMC10524016, DOI: 10.1097/aln.0000000000004593.Peer-Reviewed Original ResearchConceptsInotrope useCardiac surgeryHome medicationsAdjusted median odds ratioPulmonary circulation disordersAdult cardiac surgeryMechanical circulatory supportMedian odds ratioMedical school affiliationHome inotropesInotrope infusionInotrope therapyInotropic therapyCardiopulmonary bypassHeart failureMulticenter cohortPrimary outcomeCirculatory supportBlack raceCirculation disordersOdds ratioCommunity hospitalObservational studySame patientPatients
2022
Efficacy and Safety of Sugammadex to Shorten Time-to-Extubation Following Cardiac Surgery: A Single-Center Randomized Placebo-Controlled Trial
Bardia A, Treggiari M, Dai F, Johnson C, Singh M, Kunze K, Tickoo M, Tantawy H, Giersson A, Darr U, Schonberger R. Efficacy and Safety of Sugammadex to Shorten Time-to-Extubation Following Cardiac Surgery: A Single-Center Randomized Placebo-Controlled Trial. Critical Care Explorations 2022, 4: e0821. PMID: 36601562, PMCID: PMC9788969, DOI: 10.1097/cce.0000000000000821.Peer-Reviewed Original ResearchAortic valve replacementCardiac surgeryNeuromuscular blockadeCombined Aortic Valve ReplacementElective aortic valve replacementEfficacy of sugammadexStudy drug administrationCoronary artery bypassPlacebo-controlled trialPrimary study endpointResidual neuromuscular blockadeUse of sugammadexArtery bypassPlacebo groupSugammadex groupBaseline characteristicsValve replacementAnesthetic medicationsStudy endpointMechanical ventilationModifiable factorsCardiothoracic ICUICU settingNMB reversalPatients
2021
Trends in personal protective equipment use by clinicians performing airway procedures for patients with coronavirus disease 2019 in the USA from the intubateCOVID registry
Gaulton T, Neuman M, Investigators I, Gaulton T, Neuman M, Lane-Fall M, Gaskins L, Dattilo J, El-Boghdadly K, Wong D, Ahmad I, Johnstone C, Gutstein H, Muehlschlegel J, Hua M, Fonseca L, Mitrev L, Low Y, Gupta D, Ayad S, Volio A, Salih A, Kim D, Nutcharoen A, Skolaris A, Sherman M, Giska M, Nowak K, Chhina A, Guruswamy J, Penning D, Majewski M, Nagrebetsky A, Houle T, Aziz M, Freed J, Lien C, Mihm F, Desai P, Fahy B, Davies L, Adair K, Gunnett A, Mhyre J, Sharawi N, Applegate R, Brzenski A, Lin M, Olmos A, Chen C, Gropper M, Shochat G, Hoefnagel A, Ranganath Y, Sibenellar Z, Colquhoun D, Cloyd B, Healy D, Mathis M, Schechtman S, Steadman J, Stuart A, Bott S, Gerety L, Fisher J, Friend A, Breidenstein M, Domino K, Cervantes V, Joffe A, Dutton R, Shanahan J, Leissner K, Jaffe J, Strathman A, Khanna A, Segal B, Harris L, Fowler J, Johnson K, Hill S, Murrell M, Panzica P, Mittnacht A, Abramowicz E, Wecksell M, Schonberger R, Li J, Michel S, Treggiari M, Berstein S, Dashevksy M. Trends in personal protective equipment use by clinicians performing airway procedures for patients with coronavirus disease 2019 in the USA from the intubateCOVID registry. British Journal Of Anaesthesia 2021, 126: e184-e186. PMID: 33612248, PMCID: PMC8052559, DOI: 10.1016/j.bja.2021.01.019.Peer-Reviewed Original Research
2019
Preoperative chlorhexidine mouthwash to reduce pneumonia after cardiac surgery: A systematic review and meta-analysis
Bardia A, Blitz D, Dai F, Hersey D, Jinadasa S, Tickoo M, Schonberger RB. Preoperative chlorhexidine mouthwash to reduce pneumonia after cardiac surgery: A systematic review and meta-analysis. Journal Of Thoracic And Cardiovascular Surgery 2019, 158: 1094-1100. PMID: 30826096, DOI: 10.1016/j.jtcvs.2019.01.014.Peer-Reviewed Original ResearchConceptsPreoperative chlorhexidine mouthwashChlorhexidine gluconate mouthwashPostoperative pneumoniaCardiac surgeryChlorhexidine mouthwashHealth care burdenQuality of evidenceComprehensive systematic searchRandom-effects modelPreoperative chlorhexidineRecommendations AssessmentCommon complicationPrimary outcomePreoperative protocolPatient morbidityRisk ratioPatient outcomesCare burdenReduced riskIndependent reviewersCumulative IndexPneumoniaNLM PubMedChlorhexidine gluconatePatients
2017
The effect of race on postsurgical ambulatory medical follow-up among United States Veterans
Schonberger RB, Dai F, Brandt C, Burg MM. The effect of race on postsurgical ambulatory medical follow-up among United States Veterans. Journal Of Clinical Anesthesia 2017, 40: 55-61. PMID: 28625448, PMCID: PMC5490668, DOI: 10.1016/j.jclinane.2016.11.002.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAmbulatory CareBlack or African AmericanComorbidityContinuity of Patient CareFemaleFollow-Up StudiesHealthcare DisparitiesHumansLong-Term CareMaleMiddle AgedPatient Acceptance of Health CareRetrospective StudiesSurgical Procedures, OperativeUnited StatesVeteransVeterans HealthYoung AdultConceptsAfrican American raceAfrican American patientsInternal medicineAmerican patientsAmbulatory internal medicineAmerican raceUS Veterans Affairs hospitalsYear of surgeryDay of surgeryVeterans Affairs hospitalUnited States veteransQuality improvement initiativesRetrospective observationalUS veteransHispanic ethnicityInpatient daysStates veteransSurgeryDecreased likelihoodEffect of raceImprovement initiativesVeteransFurther studiesPatientsAfrican Americans
2014
Variation in Surgical Quality Measure Adherence within Hospital Referral Regions: Do Publicly Reported Surgical Quality Measures Distinguish among Hospitals That Patients Are Likely to Compare?
Safavi KC, Dai F, Gilbertsen TA, Schonberger RB. Variation in Surgical Quality Measure Adherence within Hospital Referral Regions: Do Publicly Reported Surgical Quality Measures Distinguish among Hospitals That Patients Are Likely to Compare? Health Services Research 2014, 49: 1108-1120. PMID: 24611578, PMCID: PMC4111773, DOI: 10.1111/1475-6773.12164.Peer-Reviewed Original ResearchMeSH KeywordsChoice BehaviorDatabases, FactualGuideline AdherenceHumansInformation DisseminationMedicarePatient PreferenceQuality ImprovementQuality Indicators, Health CareReferral and ConsultationSurgery Department, HospitalSurgical Wound InfectionUnited StatesUnited States Dept. of Health and Human ServicesConceptsHospital referral regionsSurgical quality measuresReferral regionsSurgical site infection preventionSurgical site infectionInterquartile rangePublic reporting websitesMajority of hospitalsHealth Care ProjectDepartment of HealthSite infectionAdherence ratesInfection preventionHOSPITAL scorePatient decisionMeasure adherenceSurgical providersHospitalPatientsCare ProjectDartmouth AtlasMore studiesQuality measuresHigh rateScores
2012
Atenolol is Associated With Lower Day-of-Surgery Heart Rate Compared to Long- and Short-Acting Metoprolol
Schonberger RB, Brandt C, Feinleib J, Dai F, Burg MM. Atenolol is Associated With Lower Day-of-Surgery Heart Rate Compared to Long- and Short-Acting Metoprolol. Journal Of Cardiothoracic And Vascular Anesthesia 2012, 27: 298-304. PMID: 22889605, PMCID: PMC3557658, DOI: 10.1053/j.jvca.2012.06.021.Peer-Reviewed Original ResearchMeSH KeywordsAdrenergic beta-AntagonistsAgedAmbulatory Surgical ProceduresAntihypertensive AgentsAtenololChemistry, PharmaceuticalCohort StudiesConfidence IntervalsDelayed-Action PreparationsFemaleHeart RateHemodynamicsHumansLeast-Squares AnalysisLinear ModelsMaleMetoprololMiddle AgedOutpatientsPatient CompliancePropensity ScoreTreatment OutcomeConceptsBeats/minTwice-daily dosing regimensAmbulatory surgical patientsHeart rateSurgical patientsDosing regimensMetoprolol formulationsPrimary care visitsDay of surgeryRetrospective observational studyVeterans Administration HospitalGeneral linear modelHeart rate differencesΒ-blocker typeCare visitsAdministration HospitalObservational studyPatientsMetoprololAtenololMetoprolol succinateRegimensDaysLow dayMin
2010
The Anesthesia Patient with Acute Coronary Syndrome
Schonberger RB, Haddadin AS. The Anesthesia Patient with Acute Coronary Syndrome. Anesthesiology Clinics 2010, 28: 55-66. PMID: 20400040, DOI: 10.1016/j.anclin.2010.01.001.Peer-Reviewed Original Research