2008
Behavioral differentiation between itch and pain in mouse
Shimada SG, LaMotte RH. Behavioral differentiation between itch and pain in mouse. Pain 2008, 139: 681-687. PMID: 18789837, PMCID: PMC2723192, DOI: 10.1016/j.pain.2008.08.002.Peer-Reviewed Original Research
1995
Functional changes in dorsal root ganglion cells after chronic nerve constriction in the rat
Xie Y, Zhang J, Petersen M, LaMotte R. Functional changes in dorsal root ganglion cells after chronic nerve constriction in the rat. Journal Of Neurophysiology 1995, 73: 1811-1820. PMID: 7623082, DOI: 10.1152/jn.1995.73.5.1811.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsDose-Response Relationship, DrugElectric StimulationElectrophysiologyEvoked PotentialsGanglia, SpinalNerve DegenerationNerve FibersNerve Fibers, MyelinatedNorepinephrineRatsRats, Sprague-DawleyTemperatureConceptsDorsal root gangliaChronic nerve constrictionMost C-fibersC-fibersNerve constrictionSpontaneous activityInjury siteDRG somataDorsal rootsDorsal root ganglion cellsNerve-injured ratsIpsilateral sciatic nerveL5 dorsal rootAlpha 2 receptorsEffects of norepinephrineDorsal root fibersThermal stimuliUninjured neuronsUninjured ratsNerve injurySympathetic trunkUninjured nerveSympathetic stimulationCutaneous painExcitatory responses
1991
Neurogenic hyperalgesia: the search for the primary cutaneous afferent fibers that contribute to capsaicin-induced pain and hyperalgesia
Baumann T, Simone D, Shain C, LaMotte R. Neurogenic hyperalgesia: the search for the primary cutaneous afferent fibers that contribute to capsaicin-induced pain and hyperalgesia. Journal Of Neurophysiology 1991, 66: 212-227. PMID: 1919668, DOI: 10.1152/jn.1991.66.1.212.Peer-Reviewed Original ResearchConceptsAfferent fibersNeurogenic hyperalgesiaPrimary hyperalgesiaNociceptive fibersPrimary afferentsIntradermal injectionHeat stimuliInjection siteReceptive fieldsCutaneous primary afferent fibersCapsaicin injection siteCutaneous afferent fibersNociceptive afferent fibersInjection of capsaicinCapsaicin-induced painPrimary afferent fibersPeripheral nervous systemPeripheral neural mechanismsArea of skinCapsaicin painSecondary hyperalgesiaDepressed responsivenessCapsaicin injectionIntense painHyperalgesia
1987
Hyperalgesia to heat after intradermal injection of capsaicin
Simone D, Ngeow J, Putterman G, LaMotte R. Hyperalgesia to heat after intradermal injection of capsaicin. Brain Research 1987, 418: 201-203. PMID: 3664271, DOI: 10.1016/0006-8993(87)90982-6.Peer-Reviewed Original ResearchThe Magnitude and Duration of Itch Produced by Intracutaneous Injections of Histamine
Simone D, Ngeow J, Whitehouse J, Becerra-Cabal L, Putterman G, Lamotte R. The Magnitude and Duration of Itch Produced by Intracutaneous Injections of Histamine. Somatosensory & Motor Research 1987, 5: 81-92. PMID: 3423533, DOI: 10.3109/07367228709144620.Peer-Reviewed Original ResearchConceptsDuration of itchArea of flareIntracutaneous injectionDose-dependent fashionHistamine doseMicrograms of histaminePeripheral neural mechanismsDose-dependent mannerIntracutaneous histamineItch magnitudeItch sensationLow doseItchHistamineVolar forearmDoseNeurophysiological studiesLonger durationMicrogramsMultiple injectionsInjectionNeural mechanismsDurationWeeksSubjects