1992
Pain, hyperalgesia and activity in nociceptive C units in humans after intradermal injection of capsaicin.
LaMotte R, Lundberg L, Torebjörk H. Pain, hyperalgesia and activity in nociceptive C units in humans after intradermal injection of capsaicin. The Journal Of Physiology 1992, 448: 749-764. PMID: 1593488, PMCID: PMC1176226, DOI: 10.1113/jphysiol.1992.sp019068.Peer-Reviewed Original ResearchConceptsDuration of painMagnitude of painC-nociceptorsCapsaicin injectionMechanical hyperalgesiaIntradermal injectionTopical applicationReceptive fieldsC-mechanoheat nociceptorsEffects of capsaicinMean discharge rateCutaneous hyperalgesiaHyperalgesic areaUnchanged responsivenessBackground painAlgesic substancesPeroneal nerveNociceptor excitabilityNociceptor responsesPain thresholdMechanical stimuliNociceptor dischargeIntense painConcomitant painAwake humans
1983
Psychophysical detection and pain ratings of incremental thermal stimuli: A comparison with nociceptor responses in humans
Robinson C, Torebjörk H, LaMotte R. Psychophysical detection and pain ratings of incremental thermal stimuli: A comparison with nociceptor responses in humans. Brain Research 1983, 274: 87-106. PMID: 6616259, DOI: 10.1016/0006-8993(83)90523-1.Peer-Reviewed Original ResearchConceptsMagnitude of painThermal stimuliContact thermal stimulatorMost nociceptorsNociceptive afferentsPeroneal nerveNociceptor responsesPain magnitudePain ratingsPain sensitivityPain sensationUnmyelinated fibersPainNormal skinMild burnsPsychophysical detectionDegrees CNeural responsesNociceptorsAfferentsThermal stimulatorCapacity of humansIncrement detectionDegrees C.Detection threshold
1982
Peripheral neural mechanisms of cutaneous hyperalgesia following mild injury by heat
LaMotte R, Thalhammer J, Torebjörk H, Robinson C. Peripheral neural mechanisms of cutaneous hyperalgesia following mild injury by heat. Journal Of Neuroscience 1982, 2: 765-781. PMID: 7086482, PMCID: PMC6564351, DOI: 10.1523/jneurosci.02-06-00765.1982.Peer-Reviewed Original ResearchConceptsConditioning stimulusCutaneous hyperalgesiaMild injuryDevelopment of hyperalgesiaHeat injuryMagnitude of hyperalgesiaMild heat injurySingle conditioning stimulusMagnitude of sensitizationPeripheral neural mechanismsReceptive fieldsPeroneal nervePeripheral determinantsCutaneous receptorsC-fibersAwake humansConduction blockAnesthetized monkeysHyperalgesiaNociceptorsPainGlabrous skinNormal skinInjuryHeat stimulation