Considerations of trial design and conduct in behavioral interventions for the management of chronic pain in adults
Edmond SN, Turk DC, Williams DA, Kerns RD. Considerations of trial design and conduct in behavioral interventions for the management of chronic pain in adults. PAIN Reports 2019, Publish Ahead of Print: &na;. PMID: 31583335, PMCID: PMC6749925, DOI: 10.1097/pr9.0000000000000655.Peer-Reviewed Original ResearchChronic painClinical trialsQuality of lifeLarge-scale trialsLeast modest evidenceNonpharmacological approachesPharmacological trialsClinical utilityHigh-quality researchTrial designPainMedical interventionsIntervention fidelityBehavioral interventionsTrialsBehavioral approachIntervention developmentEmotional functioningAdaptive behavioural changesAppropriate outcomesBehavioral changesInterventionModest evidencePrimary objectiveResearch design considerations