2018
Association Between Facility-Level Utilization of Non-pharmacologic Chronic Pain Treatment and Subsequent Initiation of Long-Term Opioid Therapy
Carey EP, Nolan C, Kerns RD, Ho PM, Frank JW. Association Between Facility-Level Utilization of Non-pharmacologic Chronic Pain Treatment and Subsequent Initiation of Long-Term Opioid Therapy. Journal Of General Internal Medicine 2018, 33: 38-45. PMID: 29633137, PMCID: PMC5902343, DOI: 10.1007/s11606-018-4324-y.Peer-Reviewed Original ResearchConceptsLong-term opioid therapyNon-pharmacologic treatmentsFacility-level variationNon-opioid medicationsChronic painOpioid therapyTreatment modalitiesVeterans Health Administration facilitiesPatient-reported painChronic pain treatmentChronic pain careImproved patient outcomesUtilization patternsOpioid treatmentPrior calendar yearMedication utilizationPatient characteristicsPain treatmentPain careKey ResultsAmongPrimary carePatient outcomesPainGreater utilizationAdministration facilities
2017
Interactive Voice Response–Based Self-management for Chronic Back Pain: The COPES Noninferiority Randomized Trial
Heapy AA, Higgins DM, Goulet JL, LaChappelle KM, Driscoll MA, Czlapinski RA, Buta E, Piette JD, Krein SL, Kerns RD. Interactive Voice Response–Based Self-management for Chronic Back Pain: The COPES Noninferiority Randomized Trial. JAMA Internal Medicine 2017, 177: 765-773. PMID: 28384682, PMCID: PMC5818820, DOI: 10.1001/jamainternmed.2017.0223.Peer-Reviewed Original ResearchConceptsPerson cognitive-behavioural therapyChronic back painNumeric rating scaleCognitive behavioral therapyBack painChronic painPrimary outcomeSleep qualityVeterans Affairs Health Care SystemPrespecified noninferiority marginAverage pain intensityNonpharmacologic treatment optionsPain-related interferenceChronic pain treatmentSelf-management trialCognitive behavioral therapy deliveryIndividual CBT sessionsEvidence-based treatmentsQuality of lifeSelf-help manualHealth care systemIVR monitoringNonpharmacologic interventionsSecondary outcomesStandard therapyExamining Gender as a Correlate of Self-Reported Pain Treatment Use Among Recent Service Veterans with Deployment-Related Musculoskeletal Disorders
Driscoll MA, Higgins D, Shamaskin-Garroway A, Burger A, Buta E, Goulet JL, Heapy A, Kerns RD, Brandt CA, Haskell SG. Examining Gender as a Correlate of Self-Reported Pain Treatment Use Among Recent Service Veterans with Deployment-Related Musculoskeletal Disorders. Pain Medicine 2017, 18: 1767-1777. PMID: 28379576, DOI: 10.1093/pm/pnx023.Peer-Reviewed Original ResearchConceptsPain treatment modalitiesChronic painSelf-reported useCIH servicesPain treatmentPain careMusculoskeletal conditionsTreatment modalitiesRehabilitation therapyIntegrative health servicesInterventional pain treatmentsChronic pain treatmentWomen Veterans Cohort StudyVeterans Health AdministrationMental health conditionsSelf-rated healthGender differencesSample of veteransCorrelates of SelfCohort studyPain severityCare utilizationSpecialty careTreatment useInterventional strategies
2014
Research designs for proof-of-concept chronic pain clinical trials: IMMPACT recommendations
Gewandter JS, Dworkin RH, Turk DC, McDermott MP, Baron R, Gastonguay MR, Gilron I, Katz NP, Mehta C, Raja SN, Senn S, Taylor C, Cowan P, Desjardins P, Dimitrova R, Dionne R, Farrar JT, Hewitt DJ, Iyengar S, Jay GW, Kalso E, Kerns RD, Leff R, Leong M, Petersen KL, Ravina BM, Rauschkolb C, Rice ASC, Rowbotham MC, Sampaio C, Sindrup S, Stauffer JW, Steigerwald I, Stewart J, Tobias J, Treede RD, Wallace M, White RE. Research designs for proof-of-concept chronic pain clinical trials: IMMPACT recommendations. Pain 2014, 155: 1683-1695. PMID: 24865794, PMCID: PMC4500524, DOI: 10.1016/j.pain.2014.05.025.Peer-Reviewed Original ResearchConceptsClinical trialsPain treatmentConfirmatory trialsPOC trialsChronic pain clinical trialsEfficacious pain treatmentsPain clinical trialsSingle-dose studyChronic pain treatmentConcept clinical trialPharmacokinetic-pharmacodynamic relationshipsSequential parallel comparison designIMMPACT recommendationsActive comparatorPatient populationConsensus meetingIneffective treatmentRapid onsetTrial designNovel treatmentsCrossover designTrial durationTrialsEnriched designStudy power
2012
Considerations for improving assay sensitivity in chronic pain clinical trials: IMMPACT recommendations
Dworkin RH, Turk DC, Peirce-Sandner S, Burke LB, Farrar JT, Gilron I, Jensen MP, Katz NP, Raja SN, Rappaport BA, Rowbotham MC, Backonja M, Baron R, Bellamy N, Bhagwagar Z, Costello A, Cowan P, Fang WC, Hertz S, Jay GW, Junor R, Kerns RD, Kerwin R, Kopecky EA, Lissin D, Malamut R, Markman JD, McDermott MP, Munera C, Porter L, Rauschkolb C, Rice ASC, Sampaio C, Skljarevski V, Sommerville K, Stacey BR, Steigerwald I, Tobias J, Trentacosti AM, Wasan AD, Wells GA, Williams J, Witter J, Ziegler D. Considerations for improving assay sensitivity in chronic pain clinical trials: IMMPACT recommendations. Pain 2012, 153: 1148-1158. PMID: 22494920, DOI: 10.1016/j.pain.2012.03.003.Peer-Reviewed Original ResearchConceptsRecent randomized clinical trialsClinical trialsAnalgesic treatmentChronic pain clinical trialsPain clinical trialsAnalgesic drug developmentChronic pain treatmentChronic pain trialsRandomized clinical trialsAnalgesic clinical trialsNumber of patientsEvidence-based approachIMMPACT recommendationsPain treatmentPain trialsPharmacologic treatmentAnalgesic trialsPain assessmentAssay sensitivityEfficacious medicationsConsensus meetingNegative trialsImproved efficacyStudy designTrials
2007
Interpreting the Clinical Importance of Treatment Outcomes in Chronic Pain Clinical Trials: IMMPACT Recommendations
Dworkin RH, Turk DC, Wyrwich KW, Beaton D, Cleeland CS, Farrar JT, Haythornthwaite JA, Jensen MP, Kerns RD, Ader DN, Brandenburg N, Burke LB, Cella D, Chandler J, Cowan P, Dimitrova R, Dionne R, Hertz S, Jadad AR, Katz NP, Kehlet H, Kramer LD, Manning DC, McCormick C, McDermott MP, McQuay HJ, Patel S, Porter L, Quessy S, Rappaport BA, Rauschkolb C, Revicki DA, Rothman M, Schmader KE, Stacey BR, Stauffer JW, von Stein T, White RE, Witter J, Zavisic S. Interpreting the Clinical Importance of Treatment Outcomes in Chronic Pain Clinical Trials: IMMPACT Recommendations. Journal Of Pain 2007, 9: 105-121. PMID: 18055266, DOI: 10.1016/j.jpain.2007.09.005.Peer-Reviewed Original ResearchConceptsChronic pain clinical trialsPain clinical trialsChronic pain treatmentClinical trialsSpecific outcome measuresClinical importanceTreatment outcomesOutcome measuresPain treatmentBrief Pain Inventory-InterferenceClinical trial outcome measuresPatient Global ImpressionChronic pain outcomesNumerical rating scaleTrial outcome measuresMultidimensional Pain InventoryPatient self-help organizationsBeck Depression InventoryIMMPACT recommendationsPain intensityPain outcomesPain InventoryChronic painPain assessmentGlobal Impression
2004
A critical review of the pain readiness to change model
Kerns RD, Habib S. A critical review of the pain readiness to change model. Journal Of Pain 2004, 5: 357-367. PMID: 15501193, DOI: 10.1016/j.jpain.2004.06.005.Peer-Reviewed Original Research