2001
The neurobiology of dyslexia
Shaywitz B, Shaywitz S, Pugh K, Fulbright R, Mencl W, Constable R, Skudlarski P, Fletcher J, Lyon G, Gore J. The neurobiology of dyslexia. Clinical Neuroscience Research 2001, 1: 291-299. DOI: 10.1016/s1566-2772(01)00015-9.Peer-Reviewed Original ResearchPhonological processingNeural systemsNeurobiology of dyslexiaPosterior brain systemsFrontal lobe circuitsDiagnosis of dyslexiaFunctional brain imagingDevelopment of tasksSubcomponent processesCognitive modelCognitive basisReading taskBrain systemsNeural substratesDyslexiaBrain organizationParticular subcomponentLanguage systemBrain imagingSpecific hypothesesTaskAdditional suggestionsReadingProcessingAdultsThe Functional Neural Architecture of Components of Attention in Language-Processing Tasks
Shaywitz B, Shaywitz S, Pugh K, Fulbright R, Skudlarski P, Mencl W, Constable R, Marchione K, Fletcher J, Klorman R, Lacadie C, Gore J. The Functional Neural Architecture of Components of Attention in Language-Processing Tasks. NeuroImage 2001, 13: 601-612. PMID: 11305889, DOI: 10.1006/nimg.2000.0726.Peer-Reviewed Original ResearchConceptsInferior frontal sitesFrontal sitesAttentional controlExecutive functionFunctional neural architectureFunctional magnetic resonanceLanguage processing tasksLeft hemisphere sitesSelective attentionPerceptual selectivityRight-handed manParietal sitesRight hemisphereCortical systemsLanguage processingNeural architectureFrontal cortexIncreased activationHemisphere sitesWordsTaskImportant dimensionSpecific functional aspectsAttentionProcessing
2000
The Angular Gyrus in Developmental Dyslexia: Task-Specific Differences in Functional Connectivity Within Posterior Cortex
Pugh K, Mencl W, Shaywitz B, Shaywitz S, Fulbright R, Constable R, Skudlarski P, Marchione K, Jenner A, Fletcher J, Liberman A, Shankweiler D, Katz L, Lacadie C, Gore J. The Angular Gyrus in Developmental Dyslexia: Task-Specific Differences in Functional Connectivity Within Posterior Cortex. Psychological Science 2000, 11: 51-56. PMID: 11228843, DOI: 10.1111/1467-9280.00214.Peer-Reviewed Original ResearchConceptsDevelopmental dyslexiaAngular gyrusFunctional connectivityPhonological assemblyLeft hemispherePhonological processing domainTask-specific differencesLanguage-dominant left hemispherePosterior brain regionsTemporal lobe sitesDyslexic readersNeurobiological anomaliesPhonological performanceExplicit demandDyslexiaBrain regionsGyrusPosterior cortexTaskCompensatory roleVaried demandsPosterior regionDyslexicsConnectivityHemisphere
1998
Specifying the Contributions of the Human Amygdala to Emotional Memory: A Case Study
Phelps E, Labar K, Anderson A, O'connor K, Fulbright R, Spencer D. Specifying the Contributions of the Human Amygdala to Emotional Memory: A Case Study. Neurocase 1998, 4: 527-540. DOI: 10.1080/13554799808410645.Peer-Reviewed Original ResearchEpisodic memory tasksMemory taskEpisodic memoryEmotional memoryBilateral damageEpisodic memory benefitsEffects of arousalRecognition of detailsMemory benefitsRecognition memoryFear conditioningAmygdala damageHuman amygdalaNeuromodulatory changesMemoryArousalStimuliAmygdalaSP performanceTaskDeficitsOrganizing principleEmotionsRecallValence
1997
Neuroanatomy of Reading and Dyslexia
Fulbright R, Shaywitz S, Shaywitz B, Pugh K, Skudlarski P, Constable R, Fletcher J, Liberman A, Shankweiler D, Katz L, Lacadie C, Bronen R, Marchione K, Gore J. Neuroanatomy of Reading and Dyslexia. Child And Adolescent Psychiatric Clinics Of North America 1997, 6: 431-446. DOI: 10.1016/s1056-4993(18)30312-2.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsPhonologic processingInferior frontal gyrus regionsCore cognitive componentLexical-semantic processingWord identificationNeural signaturesCognitive componentsComponent processesDyslexiaLinguistic systemGyrus regionsFunctional MR imagingConsistent findingProcessingReadingOrthographyPhonologyTaskNeuroanatomyDeficitsChildrenAdultsDisordersBrainFindingsPredicting Reading Performance From Neuroimaging Profiles: The Cerebral Basis of Phonological Effects in Printed Word Identification
Pugh K, Shaywitz B, Shaywitz S, Shankweiler D, Katz L, Fletcher J, Skudlarski P, Fulbright R, Constable R, Bronen R, Lacadie C, Gore J. Predicting Reading Performance From Neuroimaging Profiles: The Cerebral Basis of Phonological Effects in Printed Word Identification. Journal Of Experimental Psychology Human Perception & Performance 1997, 23: 299-318. PMID: 9103996, DOI: 10.1037/0096-1523.23.2.299.Peer-Reviewed Original ResearchConceptsFunctional magnetic resonance imagingPhonological effectsLexical decision taskLexical decision latenciesLexical-semantic processesBrain activation patternsWord identificationWord recognitionDecision taskDecision latenciesRegularity effectIndividual differencesFMRI measuresHemispheric lateralizationCerebral basisExperimental paradigmActivation patternsCortical regionsLength effectYoung adultsTaskParticipantsReadingMeasuresMagnetic resonance imaging
1996
Auditory Selective Attention: An fMRI Investigation
Pugh K, Shaywitz B, Shaywitz S, Fulbright R, Byrd D, Skudlarski P, Shankweiler D, Katz L, Constable R, Fletcher J, Lacadie C, Marchione K, Gore J. Auditory Selective Attention: An fMRI Investigation. NeuroImage 1996, 4: 159-173. PMID: 9345506, DOI: 10.1006/nimg.1996.0067.Peer-Reviewed Original ResearchConceptsAttention systemAnterior attention systemPosterior attention systemAuditory selective attentionInferior frontal regionsInferior frontal gyrusMiddle temporal gyrusDichotic listening conditionsSelective attentionFMRI investigationSpeech tokensPitch judgmentsFrontal gyrusListening conditionsBroca's areaTemporal gyrusNonspeech tasksHemispheric differencesFrontal regionsTone stimuliDichotic conditionsCingulate gyrusGyrusPresent experimentsTaskThe Functional Organization of Brain for Reading and Reading Disability (Dyslexia
Shaywitz B, Shaywitz S, Pugh K, Skudlarski P, Fulbright R, Constable R, Fletcher J, Liberman A, Shankweiler D, Katz L, Bronen R, Marchione K, Lacadie C, Gore J. The Functional Organization of Brain for Reading and Reading Disability (Dyslexia. The Neuroscientist 1996, 2: 245-255. DOI: 10.1177/107385849600200413.Peer-Reviewed Original ResearchFunctional magnetic resonance imagingPhonological processingLeft inferior frontal gyrusCore cognitive componentLexical-semantic processingInferior frontal gyrusFunctional organizationPhonological tasksCognitive componentsIFG regionsReading DisabilitiesFrontal gyrusComponent processesLanguage functionBilateral activationLinguistic systemWomen's performanceDyslexiaSex differencesReadingConsistent findingCerebral localizationProcessingTaskLanguage
1995
Sex differences in the functional organization of the brain for language
Shaywitz B, Shaywltz S, Pugh K, Constable R, Skudlarski P, Fulbright R, Bronen R, Fletcher J, Shankweiler D, Katz L, Gore J. Sex differences in the functional organization of the brain for language. Nature 1995, 373: 607-609. PMID: 7854416, DOI: 10.1038/373607a0.Peer-Reviewed Original ResearchConceptsLeft inferior frontal gyrus regionsInferior frontal gyrus regionsRight inferior frontal gyrusSex differencesInferior frontal gyrusFunctional organizationPattern of activationRight-handed subjectsPhonological processingPhonological tasksSemantic tasksBrain activationFrontal gyrusLanguage functionNeural systemsGyrus regionsCerebral hemispheresTaskLanguageBrainGyrusOrganizationMalesProcessingActivation