2016
Distribution of muscarinic acetylcholine receptor subtypes in the murine small intestine
Muise ED, Gandotra N, Tackett JJ, Bamdad MC, Cowles RA. Distribution of muscarinic acetylcholine receptor subtypes in the murine small intestine. Life Sciences 2016, 169: 6-10. PMID: 27866962, DOI: 10.1016/j.lfs.2016.10.030.Peer-Reviewed Original ResearchConceptsSmall intestineReceptor subtypesMuscarinic acetylcholine receptor subtypesShort bowel syndromeEffects of acetylcholineStem cell compartmentMuscarinic receptor subtypesAcetylcholine receptor subtypesSmall intestinal mucosaPotential therapeutic targetMurine small intestineCell compartmentSpecific mAChRBowel syndromeCholinergic pathwaysMyenteric plexusAnatomic distributionMuscarinic receptorsEntire alimentary tractIntestinal diseaseIntestinal mucosaEnterocyte turnoverIntestinal growthTherapeutic targetCrypt bases
2001
Functional overlap of IP3- and cADP-ribose-sensitive calcium stores in guinea pig myenteric neurons
Turner D, Segura B, Cowles R, Zhang W, Mulholland M. Functional overlap of IP3- and cADP-ribose-sensitive calcium stores in guinea pig myenteric neurons. AJP Gastrointestinal And Liver Physiology 2001, 281: g208-g215. PMID: 11408274, DOI: 10.1152/ajpgi.2001.281.1.g208.Peer-Reviewed Original ResearchMeSH KeywordsAdenosine Diphosphate RiboseAdenosine TriphosphateAnesthetics, LocalAnimalsBiological TransportCaffeineCalciumCalcium Channel BlockersCinnarizineCyclic ADP-RiboseDantroleneGuinea PigsInositol 1,4,5-TrisphosphateMicroinjectionsMuscle Relaxants, CentralMyenteric PlexusNeuronsPhosphodiesterase InhibitorsProcaineRyanodineConceptsMyenteric neuronsReceptor subtypesGuinea pig myenteric neuronsDifferent receptor subtypesMobilization of intracellularSuperfusion techniqueCalcium storesRyR antagonistSubsequent perfusionATP exposureNeuronsRyanodine receptorCADP-riboseAntagonistIntracellular microinjectionPerfusionMicroM ATPSubtypesRyRsIntracellularReceptorsTrisphosphate receptorCinnarizineSpecific ligandsMicroinjection