2007
CTGF, intestinal stellate cells and carcinoid fibrogenesis.
Kidd M, Modlin I, Shapiro M, Camp R, Mane S, Usinger W, Murren J. CTGF, intestinal stellate cells and carcinoid fibrogenesis. World Journal Of Gastroenterology 2007, 13: 5208-16. PMID: 17876891, PMCID: PMC4171302, DOI: 10.3748/wjg.v13.i39.5208.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedCarcinoid TumorCase-Control StudiesCells, CulturedConnective Tissue Growth FactorExtracellular MatrixFemaleFibrosisGastrointestinal NeoplasmsHumansImmediate-Early ProteinsIntercellular Signaling Peptides and ProteinsIntestine, SmallMaleMiddle AgedRNA, MessengerTissue Array AnalysisTransforming Growth Factor beta1ConceptsCarcinoid tumor patientsStellate cellsCarcinoid tumorsTumor patientsTissue microarrayGI carcinoid tumorsDevelopment of agentsGI carcinoidsPlasma CTGFSerum CTGFSystemic complicationsFibrotic mediatorsGastric carcinoidsHistological fibrosisPeritoneal fibrosisNormal mucosaTumor fibrosisFibrotic responseFibrosisFibrotic tissueRT-PCR analysisCTGFTGFbeta1Q-RT-PCR analysisSandwich ELISA
2006
The Role of Genetic Markers— NAP1L1, MAGE-D2, and MTA1—in Defining Small-Intestinal Carcinoid Neoplasia
Kidd M, Modlin IM, Mane SM, Camp RL, Eick G, Latich I. The Role of Genetic Markers— NAP1L1, MAGE-D2, and MTA1—in Defining Small-Intestinal Carcinoid Neoplasia. Annals Of Surgical Oncology 2006, 13: 253-262. PMID: 16424981, DOI: 10.1245/aso.2006.12.011.Peer-Reviewed Original ResearchMeSH KeywordsAdaptor Proteins, Signal TransducingAdultAgedAntigens, NeoplasmBiomarkers, TumorCarcinoid TumorCell Cycle ProteinsFemaleGenetic MarkersHistone DeacetylasesHumansIntestinal NeoplasmsIntestine, SmallMaleMiddle AgedNuclear ProteinsNucleosome Assembly Protein 1Repressor ProteinsReverse Transcriptase Polymerase Chain ReactionTissue Array AnalysisTrans-ActivatorsConceptsSmall intestinal carcinoidsQuantitative reverse transcriptase-polymerase chain reactionColorectal carcinomaMAGE-D2Primary tumorLymph node metastasisImmunohistochemical expression levelsReverse transcriptase-polymerase chain reactionNonmetastatic primary tumorsTranscriptase-polymerase chain reactionHealthy tissueGastrointestinal carcinoidsLN metastasisNode metastasisIntestinal carcinoidsPrognostic utilityHealthy mucosaMalignant potentialProstate carcinomaTissue microarrayImmunohistochemical methodsCarcinomaImmunohistochemical approachMetastasisCarcinoids
2005
Microsatellite instability and gene mutations in transforming growth factor‐beta type II receptor are absent in small bowel carcinoid tumors
Kidd M, Eick G, Shapiro MD, Camp RL, Mane SM, Modlin IM. Microsatellite instability and gene mutations in transforming growth factor‐beta type II receptor are absent in small bowel carcinoid tumors. Cancer 2005, 103: 229-236. PMID: 15599934, DOI: 10.1002/cncr.20750.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedBase Pair MismatchBase SequenceCarcinoid TumorCase-Control StudiesCohort StudiesDNA Mutational AnalysisFemaleGene Expression Regulation, NeoplasticGenomic InstabilityHumansIntestinal NeoplasmsIntestine, SmallMaleMicrosatellite RepeatsMiddle AgedMolecular Sequence DataMutationProbabilityPrognosisProtein Serine-Threonine KinasesReceptor, Transforming Growth Factor-beta Type IIReceptors, Transforming Growth Factor betaReverse Transcriptase Polymerase Chain ReactionSensitivity and SpecificityConceptsSmall bowel carcinoidsSmall bowel carcinoid tumorsCarcinoid tumorsGrowth factor beta type II receptorMicrosatellite instabilityMismatch repair genesType II receptorLiver metastasesNormal mucosaII receptorsBAT-26Carcinoid tumor metastasisVariable expressionMicrosatellite stable phenotypeRepair genes