2007
Phosphorylation of Akt (Ser473) Predicts Poor Clinical Outcome in Oropharyngeal Squamous Cell Cancer
Yu Z, Weinberger PM, Sasaki C, Egleston BL, Speier WF, Haffty B, Kowalski D, Camp R, Rimm D, Vairaktaris E, Burtness B, Psyrri A. Phosphorylation of Akt (Ser473) Predicts Poor Clinical Outcome in Oropharyngeal Squamous Cell Cancer. Cancer Epidemiology Biomarkers & Prevention 2007, 16: 553-558. PMID: 17372251, DOI: 10.1158/1055-9965.epi-06-0121.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedBiomarkers, TumorCarcinoma, Squamous CellChi-Square DistributionFemaleHumansImmunoenzyme TechniquesMaleMiddle AgedNeoplasm Recurrence, LocalOropharyngeal NeoplasmsPhosphorylationPredictive Value of TestsPrognosisProportional Hazards ModelsProtein Array AnalysisProto-Oncogene Proteins c-aktPTEN PhosphohydrolaseSurvival AnalysisConceptsNuclear p-AktAkt activationP-AktOropharyngeal squamous cell cancerSquamous cell carcinoma progressionPhosphorylated AktCohort of patientsLocal recurrence rateOverall survival rateSquamous cell cancerPoor clinical outcomeAdverse patient outcomesP-AKT levelsPromising molecular targetP-AKT expressionProtein expression levelsPhosphorylation of AktDisease recurrenceLocal recurrenceCell cancerClinical outcomesAdjusted analysisPrognostic significanceRecurrence ratePatient outcomes
2006
Q RT-PCR Detection of Chromogranin A
Kidd M, Modlin IM, Mane SM, Camp RL, Shapiro MD. Q RT-PCR Detection of Chromogranin A. Annals Of Surgery 2006, 243: 273-280. PMID: 16432362, PMCID: PMC1448909, DOI: 10.1097/01.sla.0000197734.28551.0f.Peer-Reviewed Original ResearchConceptsGI carcinoidsGI adenocarcinomasQ-RT-PCRNormal mucosaLymph node metastasisNormal lymph nodesCgA gene expressionCgA protein levelsProtein expression levelsAppendiceal tumorsNormal LNsLiver metastasesLN metastasisLymph nodesNode metastasisAppendiceal carcinoidsNonmetastatic lesionsEpithelial tumorsCgA levelsTissue microarrayTherapeutic strategiesCarcinoidsNE cellsImmunohistochemical measurementsRT-PCR detection
2000
A high number of tumor free axillary lymph nodes from patients with lymph node negative breast carcinoma is associated with poor outcome
Camp R, Rimm E, Rimm D. A high number of tumor free axillary lymph nodes from patients with lymph node negative breast carcinoma is associated with poor outcome. Cancer 2000, 88: 108-113. PMID: 10618612, DOI: 10.1002/(sici)1097-0142(20000101)88:1<108::aid-cncr15>3.0.co;2-b.Peer-Reviewed Original ResearchConceptsTumor-free lymph nodesLymph node negative breast carcinomaNode-negative breast carcinomaNegative breast carcinomaFree lymph nodesLymph nodesBreast carcinomaPrognostic valueTumor-free axillary lymph nodesTumor-negative lymph nodesDetectable lymph nodesNegative lymph nodesAxillary lymph nodesLymph node hyperplasiaLymph node metastasisReliable prognostic indicatorPresence of necrosisAxillary resectionLymphovascular invasionMetastatic diseasePatient ageIndependent predictorsLymphocytic infiltrateNode metastasisAggressive disease