2006 Donald Seldin Lecture—Molecular Genetics of Cardiovascular Risks: The Kidney as the Cause of Hypertension
Lifton R. 2006 Donald Seldin Lecture—Molecular Genetics of Cardiovascular Risks: The Kidney as the Cause of Hypertension. Circulation 2006, 114 DOI: 10.1161/circ.114.suppl_18.ii_h-a.Peer-Reviewed Original ResearchRenal salt reabsorptionDeterminants of blood pressureSalt reabsorptionBlood pressureIncreased renal salt reabsorptionMinority of patientsCause of hypertensionCongestive heart failureFamily of serine-threonine kinasesRenal salt handlingEncode ion channelsProduction of aldosteroneLower blood pressureTreatment of hypertensionBlood pressure regulationMolecular genetic analysisSerine-threonine kinaseDiuretic therapyMechanism of actionHeart failureCardiovascular riskSalt handlingHypertensionGenetic analysisKidney failure