2019
Mastering the art of epicardial access in cardiac electrophysiology
Romero J, Shivkumar K, Di Biase L, Avendano R, Anderson R, Natale A, Kumar S. Mastering the art of epicardial access in cardiac electrophysiology. Heart Rhythm 2019, 16: 1738-1749. PMID: 31015022, DOI: 10.1016/j.hrthm.2019.04.038.Peer-Reviewed Original ResearchConceptsVentricular arrhythmiasEpicardial accessEpicardial spaceRight ventricular perforationAtrial appendage occlusionAtrial fibrillation proceduresRight atrial appendageCardiac magnetic resonanceEpicardial pacing leadsVentricular perforationCoronary sinusAppendage occlusionCatheter ablationEsophageal protectionCardiac proceduresAccessory pathwayAtrial appendageNerve displacementTraditional indicationsPacing leadsSafe ablationCardiac anatomyNovel indicationsMultiple technological advancesAccess success
2018
Is it safe to stop oral anticoagulation after catheter ablation for atrial fibrillation?
Romero J, Avendano R, Diaz J, Taveras J, Lupercio F, Di Biase L. Is it safe to stop oral anticoagulation after catheter ablation for atrial fibrillation? Expert Review Of Cardiovascular Therapy 2018, 17: 31-41. PMID: 30460874, DOI: 10.1080/14779072.2019.1550718.Peer-Reviewed Original ResearchConceptsCatheter ablationAtrial fibrillationOral anticoagulantsOral anticoagulationBlanking periodRisk of bleedingSociety guidelinesCommon arrhythmiaCurrent guidelinesFibrillationAnticoagulantsRelevant articlesMajor databasesAnticoagulationAblationRiskGuidelinesBleedingEMBASEArrhythmiasPubMedStrokeMajor recommendationsPrevalenceCombined Endocardial-Epicardial Versus Endocardial Catheter Ablation Alone for Ventricular Tachycardia in Structural Heart Disease A Systematic Review and Meta-Analysis
Romero J, Cerrud-Rodriguez R, Di Biase L, Diaz J, Alviz I, Grupposo V, Cerna L, Avendano R, Tedrow U, Natale A, Tung R, Kumar S. Combined Endocardial-Epicardial Versus Endocardial Catheter Ablation Alone for Ventricular Tachycardia in Structural Heart Disease A Systematic Review and Meta-Analysis. JACC Clinical Electrophysiology 2018, 5: 13-24. PMID: 30678778, DOI: 10.1016/j.jacep.2018.08.010.Peer-Reviewed Original ResearchConceptsArrhythmogenic right ventricular cardiomyopathyVentricular tachycardiaNonischemic cardiomyopathyIschemic cardiomyopathyProcedural complicationsVT recurrenceEndocardial ablationVT ablationLower riskSystematic reviewLimited single-center studyEndocardial catheter ablationSingle-center studyAcute procedural complicationsA Systematic ReviewRight ventricular cardiomyopathyCause mortalityCatheter ablationEmbase databasesVentricular cardiomyopathyAblation strategyNonsignificant trendSubsequent mortalityPatientsMeta-AnalysisUninterrupted direct oral anticoagulants vs. uninterrupted vitamin K antagonists during catheter ablation of non-valvular atrial fibrillation: a systematic review and meta-analysis of randomized controlled trials
Romero J, Cerrud-Rodriguez R, Diaz J, Michaud G, Taveras J, Alviz I, Grupposo V, Cerna L, Avendano R, Kumar S, Kirchhof P, Natale A, Di Biase L. Uninterrupted direct oral anticoagulants vs. uninterrupted vitamin K antagonists during catheter ablation of non-valvular atrial fibrillation: a systematic review and meta-analysis of randomized controlled trials. EP Europace 2018, 20: 1612-1620. PMID: 29982383, DOI: 10.1093/europace/euy133.Peer-Reviewed Original ResearchConceptsNon-valvular atrial fibrillationUninterrupted direct oral anticoagulantsUninterrupted vitamin K antagonistsDirect oral anticoagulantsVitamin K antagonistsMajor bleeding eventsSilent cerebral infarctionThrombo-embolic eventsCatheter ablationBleeding eventsAtrial fibrillationMajor bleedingK antagonistsOral anticoagulantsSystematic reviewBrain magnetic resonance imagingMinor bleeding eventsFirst-line therapyParoxysmal atrial fibrillationRandom-effects modelMagnetic resonance imagingFixed-effects modelMinor bleedingCerebral infarctionLine therapyEarly Versus Late Referral for Catheter Ablation of Ventricular Tachycardia in Patients With Structural Heart Disease A Systematic Review and Meta-Analysis of Clinical Outcomes
Romero J, Di Biase L, Diaz J, Quispe R, Du X, Briceno D, Avendano R, Tedrow U, John R, Michaud G, Natale A, Stevenson W, Kumar S. Early Versus Late Referral for Catheter Ablation of Ventricular Tachycardia in Patients With Structural Heart Disease A Systematic Review and Meta-Analysis of Clinical Outcomes. JACC Clinical Electrophysiology 2018, 4: 374-382. PMID: 30089564, DOI: 10.1016/j.jacep.2017.12.008.Peer-Reviewed Original ResearchConceptsStructural heart diseaseEarly referralLate referralVT ablationVentricular tachycardiaAcute complicationsVT recurrenceCatheter ablationHeart diseaseTotal mortalityLong-term VT recurrenceAcute procedural successA Systematic ReviewAcute successSecondary outcomesPrimary outcomeAntiarrhythmic drugsClinical outcomesProcedural successPatient populationWorse outcomesBetter outcomesElectronic searchPatientsReferralBenefit of left atrial appendage electrical isolation for persistent and long-standing persistent atrial fibrillation: a systematic review and meta-analysis
Romero J, Michaud G, Avendano R, Briceño D, Kumar S, Diaz J, Mohanty S, Trivedi C, Gianni C, Della Rocca D, Proietti R, Perrotta L, Bordignon S, Chun J, Schmidt B, Garcia M, Natale A, Di Biase L. Benefit of left atrial appendage electrical isolation for persistent and long-standing persistent atrial fibrillation: a systematic review and meta-analysis. EP Europace 2018, 20: 1268-1278. PMID: 29342299, DOI: 10.1093/europace/eux372.Peer-Reviewed Original ResearchConceptsAtrial appendage electrical isolationPersistent atrial fibrillationAtrial fibrillationIschemic strokeSystematic reviewNon-paroxysmal AF patientsStandard ablationNon-paroxysmal atrial fibrillationAcute procedural complicationsIncremental benefitAcute complication rateLong-term outcomesAntiarrhythmic medicationsArrhythmia recurrenceComplication rateAF patientsProcedural complicationsCatheter ablationAtrial arrhythmiasClinical studiesOverall freedomLAAEIPatientsLSPAFFibrillation