Sanger sequencing and deconvolution of polyclonal infections: a quantitative approach to monitor drug-resistant Plasmodium falciparum
Maiga H, Morrison R, Duffy P. Sanger sequencing and deconvolution of polyclonal infections: a quantitative approach to monitor drug-resistant Plasmodium falciparum. EBioMedicine 2024, 103: 105115. PMID: 38636200, PMCID: PMC11031737, DOI: 10.1016/j.ebiom.2024.105115.Peer-Reviewed Original ResearchConceptsDrug resistance genesNational Institutes of HealthBill & Melinda Gates FoundationPlasmodium falciparumAnti-malarial drug resistanceDrug-resistant Plasmodium falciparumSanger sequencingSanger sequencing of PCR ampliconsAnti-malarial resistanceAntimalarial drug sensitivityMalaria-endemic regionsNational Institute of AllergySequencing of PCR ampliconsInstitute of AllergyPfdhps allelesPfdhps genesUS National Institutes of HealthPublic health problemPolyclonal infectionsSequencing chromatogramsField samplesPopulation-based surveyDrug sensitivityMelinda Gates FoundationDrug resistance