2021
AMH Highly Correlates With Cumulative Live Birth Rate in Women with Diminished Ovarian Reserve Independent of Age*
Tal R, Seifer DB, Tal R, Granger E, Wantman E, Tal O. AMH Highly Correlates With Cumulative Live Birth Rate in Women with Diminished Ovarian Reserve Independent of Age*. The Journal Of Clinical Endocrinology & Metabolism 2021, 106: 2754-2766. PMID: 33729496, DOI: 10.1210/clinem/dgab168.Peer-Reviewed Original ResearchConceptsCumulative live birth rateDiminished ovarian reserveLive birth rateSerum AMHLive birthsAge strataRetrieval cycleAntimüllerian hormone levelsReproductive technology cyclesCumulative live birthMain outcome measuresMultiple logistic regressionNumber of oocytesBirth rateRegression analysisPreimplantation genetic testingAddition of AMHPercentage of cyclesOvarian reserveIndependent predictorsOvarian responseHormone levelsRetrospective analysisOutcome measuresEmbryo transfer
2018
Same-day confirmation of intrauterine pregnancy failure in women with first- and early second-trimester bleeding
Mor A, Tal R, Haberman S, Kalgi B, Nasab SH, Minkoff H. Same-day confirmation of intrauterine pregnancy failure in women with first- and early second-trimester bleeding. Fertility And Sterility 2018, 109: 1060-1064. PMID: 29935643, DOI: 10.1016/j.fertnstert.2018.02.006.Peer-Reviewed Original ResearchMeSH KeywordsAbortion, IncompleteAbortion, LegalAbortion, SpontaneousAbortion, ThreatenedAdultAlpha-FetoproteinsBlood Chemical AnalysisCerclage, CervicalDilatation and CurettageFemaleHumansMaternal Serum Screening TestsPregnancyPregnancy Trimester, FirstPregnancy Trimester, SecondReproducibility of ResultsSensitivity and SpecificityTime FactorsUterine HemorrhageVaginaConceptsMaternal serumVaginal bloodVaginal bleedingFetal tissuesSecond trimester bleedingProspective cohort studyAlpha-fetoprotein concentrationAFP concentrationProducts of conceptionGroup of womenCerclage groupCerclage placementCohort studyIncomplete miscarriagePregnancy failureMedical CenterMAIN OUTCOMEBleedingMiscarriageBloodSerumAFPTissueWomenCharacteristic analysisAntimüllerian hormone as a predictor of live birth following assisted reproduction: an analysis of 85,062 fresh and thawed cycles from the Society for Assisted Reproductive Technology Clinic Outcome Reporting System database for 2012–2013
Tal R, Seifer DB, Wantman E, Baker V, Tal O. Antimüllerian hormone as a predictor of live birth following assisted reproduction: an analysis of 85,062 fresh and thawed cycles from the Society for Assisted Reproductive Technology Clinic Outcome Reporting System database for 2012–2013. Fertility And Sterility 2018, 109: 258-265. PMID: 29331235, DOI: 10.1016/j.fertnstert.2017.10.021.Peer-Reviewed Original ResearchAdultAnti-Mullerian HormoneArea Under CurveBiomarkersChi-Square DistributionCryopreservationDatabases, FactualEmbryo TransferFemaleFertilization in VitroHumansInfertilityLive BirthLogistic ModelsMaleOdds RatioPregnancyPregnancy RateRetrospective StudiesRisk FactorsROC CurveSingle Embryo TransferTime FactorsTreatment Outcome
2015
Carcinoembryonic antigen as a biomarker for meconium‐stained amniotic fluid
Mor A, Tal R, Irani M, McCalla S, Haberman S, Garg D, Wajntraub B. Carcinoembryonic antigen as a biomarker for meconium‐stained amniotic fluid. International Journal Of Gynecology & Obstetrics 2015, 132: 329-331. PMID: 26674317, DOI: 10.1016/j.ijgo.2015.07.032.Peer-Reviewed Original ResearchConceptsMeconium-stained amniotic fluidClear amniotic fluidAmniotic fluidCEA concentrationHigh CEA concentrationsMean CEA concentrationsTerm singleton pregnanciesProspective cohort studyRupture of membranesClear medical indicationCarcinoembryonic antigen concentrationCharacteristic curve analysisAmniotic fluid statusCEA cutoffSingleton pregnanciesCohort studyArtificial ruptureBedside testFluid statusNormal rangeMedical indicationsCarcinoembryonic antigenAntigen concentrationCurve analysisOnly womenVitamin D Supplementation Decreases TGF-β1 Bioavailability in PCOS: A Randomized Placebo-Controlled Trial
Irani M, Seifer DB, Grazi RV, Julka N, Bhatt D, Kalgi B, Irani S, Tal O, Lambert-Messerlian G, Tal R. Vitamin D Supplementation Decreases TGF-β1 Bioavailability in PCOS: A Randomized Placebo-Controlled Trial. The Journal Of Clinical Endocrinology & Metabolism 2015, 100: 4307-4314. PMID: 26485217, DOI: 10.1210/jc.2015-2580.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAntigens, CDBiological AvailabilityCholecalciferolDehydroepiandrosterone SulfateEndoglinFemaleHumansInsulin ResistanceLipidsPolycystic Ovary SyndromeProspective StudiesReceptors, Cell SurfaceSocioeconomic FactorsTestosteroneTransforming Growth Factor beta1Vitamin DVitamin D DeficiencyVitaminsYoung AdultConceptsPolycystic ovary syndromeVD supplementationTGF-β1Clinical manifestationsClinical parametersAcademic-affiliated medical centerFerriman-Gallwey scoreOral vitamin D3Serum TGF-β1Soluble endoglin levelsPlacebo-controlled trialVitamin D supplementationTGF-β1 levelsNew treatment modalitiesD supplementationOral placeboRandomized PlaceboOvary syndromeVD levelsEndoglin levelsInsulin resistanceTreatment modalitiesMenstrual periodLipid profileVitamin D3Acute presentation of gestational diabetes insipidus with pre‐eclampsia complicated by cerebral vasoconstriction: A case report and review of the published work
Mor A, Fuchs Y, Zafra K, Haberman S, Tal R. Acute presentation of gestational diabetes insipidus with pre‐eclampsia complicated by cerebral vasoconstriction: A case report and review of the published work. Journal Of Obstetrics And Gynaecology Research 2015, 41: 1269-1272. PMID: 25832854, DOI: 10.1111/jog.12694.Peer-Reviewed Original ResearchConceptsGestational diabetes insipidusCerebral vasoconstrictionLiver dysfunctionDiabetes insipidusImpaired liver functionSelf-limiting complicationsMagnetic resonance angiographyAcute presentationPregnancy complicationsRenal insufficiencyCesarean sectionSevere featuresWeeks' gestationLiver functionCase reportHigh indexResonance angiographyTypical signsVasoconstrictionComplicationsPregnancyGestationInsipidusDysfunctionPatients
2014
Antimüllerian hormone as predictor of implantation and clinical pregnancy after assisted conception: a systematic review and meta-analysis
Tal R, Tal O, Seifer BJ, Seifer DB. Antimüllerian hormone as predictor of implantation and clinical pregnancy after assisted conception: a systematic review and meta-analysis. Fertility And Sterility 2014, 103: 119-130.e3. PMID: 25450298, DOI: 10.1016/j.fertnstert.2014.09.041.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnti-Mullerian HormoneBiomarkersEmbryo ImplantationFemaleFertilization in VitroHumansInfertility, FemaleMiddle AgedObservational Studies as TopicOvarian ReserveOvaryOvulation InductionPregnancyPregnancy OutcomePregnancy RatePrevalenceReproducibility of ResultsRisk FactorsSensitivity and SpecificityYoung AdultConceptsPredictor of implantationClinical pregnancy rateAntimüllerian hormoneClinical pregnancyOvarian reservePregnancy rateOdds ratioIVF/intracytoplasmic sperm injectionSystematic reviewSerum AMH levelsPolycystic ovary syndromeReproductive technologiesIntracytoplasmic sperm injectionNondonor cyclesAMH levelsOvary syndromeImplantation rateDiagnostic odds ratioObservational studyMAIN OUTCOMEClinical utilitySperm injectionPregnancyAssisted conceptionFertility treatmentCharacterization of women with elevated antimüllerian hormone levels (AMH): correlation of AMH with polycystic ovarian syndrome phenotypes and assisted reproductive technology outcomes
Tal R, Seifer DB, Khanimov M, Malter HE, Grazi RV, Leader B. Characterization of women with elevated antimüllerian hormone levels (AMH): correlation of AMH with polycystic ovarian syndrome phenotypes and assisted reproductive technology outcomes. American Journal Of Obstetrics And Gynecology 2014, 211: 59.e1-59.e8. PMID: 24593938, DOI: 10.1016/j.ajog.2014.02.026.Peer-Reviewed Original ResearchConceptsSerum antimüllerian hormone levelsAntimüllerian hormone levelsClinical pregnancy ratePopulation of womenAMH levelsPregnancy rateHormone levelsHigher clinical pregnancy rateElevated AMH levelsPresence of amenorrheaMultiple pregnancy rateOvarian hyperstimulation syndromeRetrospective cohort studyHigher AMH levelsPolycystic ovarian morphologyPolycystic ovarian syndromeSyndrome phenotypeReproductive technology outcomesHyperstimulation syndromePCOS severityClinical pregnancyOvarian stimulationTotal testosteroneCohort studyOvarian syndrome
2013
Transforming growth factor-β1 and its receptor soluble endoglin are altered in polycystic ovary syndrome during controlled ovarian stimulation
Tal R, Seifer DB, Shohat-Tal A, Grazi RV, Malter HE. Transforming growth factor-β1 and its receptor soluble endoglin are altered in polycystic ovary syndrome during controlled ovarian stimulation. Fertility And Sterility 2013, 100: 538-543. PMID: 23684116, DOI: 10.1016/j.fertnstert.2013.04.022.Peer-Reviewed Original ResearchMeSH KeywordsAdultAntigens, CDCase-Control StudiesEndoglinFemaleFertilization in VitroFollicular FluidHumansInfertility, FemaleOvarian Hyperstimulation SyndromeOvulation InductionPolycystic Ovary SyndromeReceptors, Cell SurfaceSperm Injections, IntracytoplasmicTransforming Growth Factor beta1UltrasonographyYoung AdultConceptsPolycystic ovarian syndromeSerum soluble endoglinDay of hCGSoluble endoglinFollicular fluidTGF-β1Oocyte retrievalOvarian stimulationHCG administrationControl womenDay 3Pathogenesis of PCOSNon-PCOS control groupProspective case-control studyNon-PCOS controlsSerum TGF-β1Non-PCOS womenPolycystic ovary syndromeTGF-β1 levelsReproductive technology unitCase-control studyGrowth factor-β1Day of retrievalOvarian hyperstimulationOvarian syndrome