2022
The Role of Angiogenic Factor Dysregulation in the Pathogenesis of Polycystic Ovarian Syndrome
Chen A, Seifer D, Tal R. The Role of Angiogenic Factor Dysregulation in the Pathogenesis of Polycystic Ovarian Syndrome. 2022, 449-487. DOI: 10.1007/978-3-030-92589-5_23.Peer-Reviewed Original ResearchPolycystic ovarian syndromeOvulatory dysfunctionGrowth factorOvarian syndromePathophysiology of PCOSAngiogenic factorsAbnormal endometrial receptivityPCOS animal modelsOvarian hyperstimulation syndromeReproductive-age womenMenstrual cycle functionVascular endothelial growth factorNormal follicular developmentComplex endocrine disorderPlatelet-derived growth factorBasic fibroblast growth factorEndothelial growth factorFibroblast growth factorAngiogenesis dysfunctionHyperstimulation syndromeAngiogenic imbalancePCOS patientsPCOS managementPolycystic ovariesAngiogenesis-based therapiesChapter 23 Polycystic ovarian syndrome and reproductive failure
Duero J, Tal R. Chapter 23 Polycystic ovarian syndrome and reproductive failure. 2022, 351-378. DOI: 10.1016/b978-0-323-90805-4.00009-2.ChaptersPolycystic ovarian syndromeInsulin resistanceOvarian syndromeEndometrial receptivityUterine abnormalitiesReproductive dysfunctionPathophysiology of PCOSRecurrent pregnancy lossReproductive-age womenAbnormal follicular developmentRisk of obesityComplex endocrine disorderEndometrial gene expressionMajority of womenType II diabetesPregnancy complicationsPolycystic ovariesPreterm birthPlacental dysfunctionChronic inflammationClinical manifestationsEndocrine disordersImplantation failurePregnancy lossCardiovascular disease
2015
The Emerging Role of Angiogenic Factor Dysregulation in the Pathogenesis of Polycystic Ovarian Syndrome
Tal R, Seifer DB, Arici A. The Emerging Role of Angiogenic Factor Dysregulation in the Pathogenesis of Polycystic Ovarian Syndrome. Seminars In Reproductive Medicine 2015, 33: 195-207. PMID: 26036901, DOI: 10.1055/s-0035-1552582.Peer-Reviewed Original ResearchConceptsPolycystic ovarian syndromeGrowth factorOvarian syndromePathophysiology of PCOSAngiogenic factor imbalanceOvarian hyperstimulation syndromeCommon endocrine disorderVascular endothelial growth factorPlatelet-derived growth factorBasic fibroblast growth factorMultiple angiogenic factorsEndothelial growth factorFibroblast growth factorHyperstimulation syndromeOvulatory dysfunctionStromal vascularityAnovulatory infertilityPolycystic ovariesEndocrine disordersReproductive ageTreatment strategiesFollicular growthOvarian angiogenesisAngiogenic factorsCorpus luteum