Featured Publications
Pressure-Regulated Ventilator Splitting for Disaster Relief: Design, Testing, and Clinical Experience
Raredon MSB, Fisher C, Heerdt PM, Schonberger RB, Nargi A, Nivison S, Fajardo E, Deshpande R, Akhtar S, Greaney AM, Belter J, Raredon T, Zinter J, McKee A, Michalski M, Baevova P, Niklason LE. Pressure-Regulated Ventilator Splitting for Disaster Relief: Design, Testing, and Clinical Experience. Anesthesia & Analgesia 2021, 134: 1094-1105. PMID: 34928890, DOI: 10.1213/ane.0000000000005825.Peer-Reviewed Original ResearchConceptsPositive end-expiratory pressureClinical experienceIndividualized positive end-expiratory pressureIntensive care unitEnd-expiratory pressureCoronavirus disease 2019 (COVID-19) pandemicHealth care teamDisease 2019 pandemicVentilatory supportIll patientsCare unitCare teamVentilator sharingFuture clinical applicationsPatientsIndependent careVentilator capacityClinical applicationCOVID-19 pandemicVentilatorClinical environmentOutline recommendationsMass traumaPandemicHospitalIntubation and Ventilation amid the COVID-19 Outbreak
Meng L, Qiu H, Wan L, Ai Y, Xue Z, Guo Q, Deshpande R, Zhang L, Meng J, Tong C, Liu H, Xiong L. Intubation and Ventilation amid the COVID-19 Outbreak. Anesthesiology 2020, 132: 10.1097/aln.0000000000003296. PMID: 32195705, PMCID: PMC7155908, DOI: 10.1097/aln.0000000000003296.Peer-Reviewed Original ResearchConceptsHigh-flow oxygen therapyPositive airway pressure ventilationCOVID-19Prone position ventilationLung-protective ventilationRapid sequence inductionCOVID-19 outbreakIntubation strategyInvasive ventilationAdequate sedationDisease courseOxygen therapyIll patientsPressure ventilationSequence inductionRapid intubationIntubationVideo laryngoscopeEnhanced riskPatientsVentilation managementVentilationOxygen debtWuhanOutbreakLiver allocation and distribution
Deshpande R, Hirose R, Mulligan D. Liver allocation and distribution. Current Opinion In Organ Transplantation 2017, 22: 162-168. PMID: 28212159, DOI: 10.1097/mot.0000000000000397.Peer-Reviewed Original ResearchConceptsTransplant CommitteeTransplant centersEnd-Stage Liver Disease (MELD) pointsLiver allograft allocationDeceased donor liversLife-saving organsLiver allocation policyAllograft allocationLiver transplantLiver transplantationLiver diseaseDonor liversUnited NetworkDonor organsLiver distributionAdvanced stageLiver allocationOrgan distributionPatient accessTransplantationGeographic disparitiesLiverDisease pointHealthcare systemPatientsProcedural sedation in the ICU and emergency department
Chawla N, Boateng A, Deshpande R. Procedural sedation in the ICU and emergency department. Current Opinion In Anaesthesiology 2017, 30: 507-512. PMID: 28562388, DOI: 10.1097/aco.0000000000000487.Peer-Reviewed Original ResearchConceptsProcedural sedationEmergency departmentSedation ScaleOperating roomCommon adverse eventsOutcomes of patientsPhase 2 trialUse of capnographyBetter patient satisfactionAcute care settingMultidisciplinary team approachEmergency department settingAddition of ketamineProceduralist satisfactionSynergistic sedationPulmonary aspirationAdverse eventsPatient satisfactionDepartment settingPharmacologic agentsCare settingsSedationMultidisciplinary teamTeam approachCurrent safety guidelinesRegional anesthesia for transplantation surgery – A white paper part 1: Thoracic transplantation surgery
Ander M, Mugve N, Crouch C, Kassel C, Fukazawa K, Izaak R, Deshpande R, McLendon C, Huang J. Regional anesthesia for transplantation surgery – A white paper part 1: Thoracic transplantation surgery. Clinical Transplantation 2023, 37: e15043. PMID: 37306898, PMCID: PMC10834230, DOI: 10.1111/ctr.15043.Peer-Reviewed Original ResearchConceptsTransplantation surgeryRegional anesthesiaOpioid usePostoperative pain controlRegional anesthetic techniquesAnalgesic modalitiesAnalgesic effectivenessPain controlSurgery protocolNeuraxial blockPatient's hemodynamicsAnesthetic techniqueAbdominal transplantationTransplant anesthesiaSurgeryAnesthesiaSystemic reviewEnhanced recoveryTransplant techniquesPerioperative culturesLiterature searchFormal guidelinesAvailable literatureUltrasound machineTask ForceRelationship Between Glucose Time in Range in Diabetic and Non-Diabetic Patients and Mortality in Critically Ill Patients
Ammar MA, Ammar AA, Wee T, Deshpande R, Band M, Akhtar S. Relationship Between Glucose Time in Range in Diabetic and Non-Diabetic Patients and Mortality in Critically Ill Patients. Journal Of Intensive Care Medicine 2022, 37: 1625-1633. PMID: 35491687, DOI: 10.1177/08850666221098383.Peer-Reviewed Original ResearchConceptsNon-diabetic patientsBlood glucose rangeDiabetic patientsIll patientsGlucose rangeTIR 70Hospital mortalityMortality rateHospital mortality rateNon-diabetic cohortLower mortality rateAdult patientsCohort studyMortality benefitSingle centerGlucose timePercentage of timeHigh incidencePatientsMortalityDlLtDiabeticsICUHyperglycemiaTreatments Associated with Lower Mortality among Critically Ill COVID-19 Patients: A Retrospective Cohort Study
Zhao X, Gao C, Dai F, Treggiari MM, Deshpande R, Meng L. Treatments Associated with Lower Mortality among Critically Ill COVID-19 Patients: A Retrospective Cohort Study. Anesthesiology 2021, 135: 1076-1090. PMID: 34597362, DOI: 10.1097/aln.0000000000003999.Peer-Reviewed Original ResearchConceptsIll COVID-19 patientsCOVID-19 patientsPropensity score-matched analysisRetrospective cohort studyLower mortalityHospital mortalityCohort studyMultivariable analysisYale New Haven Health SystemIntensive care unit admissionOrgan support treatmentUse of apixabanCare unit admissionSevere COVID-19Intensive care unitCOVID-19 mortalityLower COVID-19 mortalityApixaban treatmentUnit admissionAspirin treatmentCare unitTreatment AssociatedCandidate treatmentSupport treatmentPatientsCurrent approach to diagnosis and treatment of delirium after cardiac surgery
Evans AS, Weiner MM, Arora RC, Chung I, Deshpande R, Varghese R, Augoustides J, Ramakrishna H. Current approach to diagnosis and treatment of delirium after cardiac surgery. Annals Of Cardiac Anaesthesia 2016, 19: 328-337. PMID: 27052077, PMCID: PMC4900348, DOI: 10.4103/0971-9784.179634.Peer-Reviewed Original ResearchTraining the Anesthesiologist in Point-of-Care Ultrasound
Deshpande R, Montealegre-Gallegos M, Matyal R, Belani K, Chawla N. Training the Anesthesiologist in Point-of-Care Ultrasound. International Anesthesiology Clinics 2016, 54: 71-93. PMID: 26655510, DOI: 10.1097/aia.0000000000000088.Peer-Reviewed Original Research
2024
Regional anesthesia for transplantation surgery ‐ A White Paper Part 2: Abdominal transplantation surgery
Ander M, Mugve N, Crouch C, Kassel C, Fukazawa K, Isaak R, Deshpande R, McLendon C, Huang J. Regional anesthesia for transplantation surgery ‐ A White Paper Part 2: Abdominal transplantation surgery. Clinical Transplantation 2024, 38: e15227. PMID: 38289879, DOI: 10.1111/ctr.15227.Peer-Reviewed Original ResearchConceptsSociety for the Advancement of Transplant AnesthesiaTransplant surgeryRegional anesthesiaPostoperative pain controlRegional anesthetic techniquesDevelopment of enhanced recoveryAvailability of ultrasound machinesAbdominal transplantationOpioid usePain controlAnalgesic effectNeuraxial blockPerioperative culturesPatient's hemodynamicsSurgeryUterus transplantationAnesthetic techniqueTransplantationReview available literatureAdvancement of Transplant AnesthesiaSystemic reviewTransplantation techniquesAnesthesiaLiterature searchUltrasound machine
2023
Perioperative Fluid Management and Volume Assessment
Elia J, Diwan M, Deshpande R, Brainard J, Karamchandani K. Perioperative Fluid Management and Volume Assessment. Anesthesiology Clinics 2023, 41: 191-209. PMID: 36871999, DOI: 10.1016/j.anclin.2022.10.010.Peer-Reviewed Original ResearchConceptsPerioperative fluid managementFluid managementFluid responsivenessFluid therapyAdequate organ perfusionIntraoperative fluid managementEvidence-based recommendationsCardiac preloadPerioperative careVolume statusVolume responsivenessStroke volumeOrgan perfusionBlood volumeVolume assessmentTherapyResponsivenessAccurate assessmentManagement
2021
The Society for the Advancement of Transplant Anesthesia (SATA) enters a new partnership with Clinical Transplantation
Mandell MS, Sakai T, Wagener G, De Marchi L, Subramaniam K, JHuang J, Hendrickse A, Deshpande R, Ryan C, Pretto EA. The Society for the Advancement of Transplant Anesthesia (SATA) enters a new partnership with Clinical Transplantation. Clinical Transplantation 2021, 35: e14203. PMID: 33475197, DOI: 10.1111/ctr.14203.Peer-Reviewed Original Research
2020
Resource Utilization in Implementation of a Point of Care Ultrasound Curriculum for Resident Training in Anesthesiology.
Deshpande R, Karnik R, Baer C, Kurup V. Resource Utilization in Implementation of a Point of Care Ultrasound Curriculum for Resident Training in Anesthesiology. The Yale Journal Of Biology And Medicine 2020, 93: 423-427. PMID: 32874148, PMCID: PMC7448394.Peer-Reviewed Original ResearchAnesthesia at the Edge of Life
Deshpande R, Rosenbaum SH. Anesthesia at the Edge of Life. Anesthesiology Clinics 2020, 38: xv-xvi. PMID: 32008661, DOI: 10.1016/j.anclin.2019.12.001.Peer-Reviewed Original Research
2019
Perioperative Hypertensive Urgency After Methylene Blue in a Patient With Undiagnosed Pheochromocytoma
Shukla S, Zhu R, Rubin P, Deshpande R. Perioperative Hypertensive Urgency After Methylene Blue in a Patient With Undiagnosed Pheochromocytoma. A&A Practice 2019, Publish Ahead of Print: &na;. PMID: 30431442, DOI: 10.1213/xaa.0000000000000924.Peer-Reviewed Original ResearchConceptsUndiagnosed pheochromocytomaSurgical intensive care unit admissionIntensive care unit admissionRobotic-assisted laparoscopic hysterectomyMethylene blue administrationCare unit admissionHypertensive urgencyPerioperative hypertensionBlue administrationPerioperative coursePersistent hypertensionPheochromocytoma crisisUnit admissionLaparoscopic hysterectomyAnesthetic careDifferential diagnosisPatientsInvestigative evaluationHypertensionPheochromocytomaHysterectomyAdmissionTumorsDiagnosisAdministration
2017
Perioperative point of care ultrasound in ambulatory anesthesia
Deshpande R, Ramsingh D. Perioperative point of care ultrasound in ambulatory anesthesia. Current Opinion In Anaesthesiology 2017, 30: 663-669. PMID: 29016368, DOI: 10.1097/aco.0000000000000529.Peer-Reviewed Original ResearchConceptsCare ultrasoundPerioperative pointUses of ultrasoundAcute care medicinePerioperative periodAmbulatory anesthesiaPatient outcomesRegional anesthesiaCritical careEmergency physiciansCare medicineCommon conditionCare ultrasound trainingPerioperative areaPerioperative arenaUltrasoundAnesthesiaRecent dataUltrasound trainingPhysiciansAnesthesiology residencyPersistent Left Superior Vena Cava
Deshpande R, Band M, Kurup V. Persistent Left Superior Vena Cava. Anesthesiology 2017, 127: 165. PMID: 28187019, DOI: 10.1097/aln.0000000000001567.Peer-Reviewed Original Research
2014
Utility of ultrasound in the ICU
Deshpande R, Akhtar S, Haddadin AS. Utility of ultrasound in the ICU. Current Opinion In Anaesthesiology 2014, 27: 123-132. PMID: 24589673, DOI: 10.1097/aco.0000000000000057.Peer-Reviewed Original ResearchConceptsAcute care settingPerioperative periodCare settingsAxillary vein cannulationUtility of ultrasoundImportant diagnostic modalityLung recruitmentPerioperative managementExtubation strategyUnstable patientsAbdominal examinationInferior venaDiaphragmatic movementLung ultrasoundVascular diseaseEndotracheal tubeCritical patientsVein cannulationCardiopulmonary resuscitationUltrasound guidanceDiagnostic modalitiesCare ultrasoundCardiac structureAbdominal organsPatient care