2005
Nav1.6 channels generate resurgent sodium currents in spinal sensory neurons
Cummins TR, Dib-Hajj SD, Herzog RI, Waxman SG. Nav1.6 channels generate resurgent sodium currents in spinal sensory neurons. FEBS Letters 2005, 579: 2166-2170. PMID: 15811336, DOI: 10.1016/j.febslet.2005.03.009.Peer-Reviewed Original ResearchConceptsResurgent sodium currentsResurgent currentsDRG neuronsLarge-diameter dorsal root ganglion neuronsSodium currentDorsal root ganglion neuronsSmall DRG neuronsSpinal sensory neuronsWild-type miceCerebellar Purkinje neuronsVoltage-gated sodium channelsGanglion neuronsSensory neuronsPurkinje neuronsNull miceNav1.6 channelsNeuronsSodium channelsMiceCell background
2001
Persistent TTX-Resistant Na+ Current Affects Resting Potential and Response to Depolarization in Simulated Spinal Sensory Neurons
Herzog RI, Cummins TR, Waxman SG. Persistent TTX-Resistant Na+ Current Affects Resting Potential and Response to Depolarization in Simulated Spinal Sensory Neurons. Journal Of Neurophysiology 2001, 86: 1351-1364. PMID: 11535682, DOI: 10.1152/jn.2001.86.3.1351.Peer-Reviewed Original ResearchConceptsPersistent TTX-R currentTTX-R currentsSmall DRG neuronsSodium currentDRG neuronsSmall dorsal root ganglion neuronsTTX-resistant sodium currentsDorsal root ganglion neuronsVoltage-gated sodium currentTetrodotoxin-sensitive sodium currentTTX-S currentsSpinal sensory neuronsGanglion neuronsNeuronal excitabilitySensory neuronsAction potentialsNeuronsSubthreshold stimuliDepolarizing phaseSpike electrogenesisAnode break excitationElectrogenic propertiesBreak excitationPossible contributionInactivation gate