2003
The Tertiary Structure and Backbone Dynamics of Human Prolactin
Keeler C, Dannies PS, Hodsdon ME. The Tertiary Structure and Backbone Dynamics of Human Prolactin. Journal Of Molecular Biology 2003, 328: 1105-1121. PMID: 12729745, DOI: 10.1016/s0022-2836(03)00367-x.Peer-Reviewed Original ResearchConceptsFour-dimensional heteronuclear NMR spectroscopyTertiary structureBackbone dynamicsFour-helical bundleN-terminal loopSecretory granulesHeteronuclear NMR spectroscopyExtrapituitary prolactinNMR relaxation phenomenaThird helixFirst helixSecond helixGolgi complexFunctional bindingHematopoietic cytokinesBundle topologyDiscrete structural differencesFemale reproductive systemHuman prolactinProlactin receptorReversible oligomerizationHelixShort loopsReproductive systemGrowth factor
1988
Estrogen induces accumulation of the mitochondrial ribonucleic acid for subunit II of cytochrome oxidase in pituitary tumor cells.
Van Itallie C, Dannies P. Estrogen induces accumulation of the mitochondrial ribonucleic acid for subunit II of cytochrome oxidase in pituitary tumor cells. Endocrinology 1988, 2: 332-7. PMID: 2837664, DOI: 10.1210/mend-2-4-332.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBase SequenceCell DivisionDNADNA, RecombinantElectron Transport Complex IVEnzyme InductionEpidermal Growth FactorEstradiolFemaleInsulinMaleMitochondriaMolecular Sequence DataNucleic Acid HybridizationPituitary NeoplasmsProlactinRatsRats, Inbred StrainsRNA, MessengerTumor Cells, CulturedConceptsCytochrome oxidase II geneCytochrome oxidaseMitochondrial ribonucleic acidMitochondrial genomePituitary tumor cell lineEpidermal growth factorMRNA accumulationNumber of copiesTumor cell linesPituitary tumor cellsCell proliferationMRNACell linesRibonucleic acidMaximal inductionGenesGrowth factorGrowth ratePRL mRNA
1986
Antiestrogens are partial estrogen agonists for prolactin production in primary pituitary cultures
Martinez-Campos A, Amara J, Dannies P. Antiestrogens are partial estrogen agonists for prolactin production in primary pituitary cultures. Molecular And Cellular Endocrinology 1986, 48: 127-133. PMID: 3803705, DOI: 10.1016/0303-7207(86)90035-3.Peer-Reviewed Original ResearchConceptsProlactin productionPituitary cellsMale rat anterior pituitary cellsRat anterior pituitary cellsPartial estrogen agonistNormal pituitary cellsAnterior pituitary cellsConcentrations of estradiolDose-response relationshipPrimary pituitary culturesEstrogen antagonistLY 117018Estrogen agonistM tamoxifenPartial agonistPituitary culturesEstrogen inductionTamoxifenMaximal stimulationFull antagonistM LysPrimary culturesStimulationPimozideAgonistsA possible differentiation of anterior pituitary cells in collagen gels into neurons
Martinez-Campos A, Dannies P. A possible differentiation of anterior pituitary cells in collagen gels into neurons. Cell And Tissue Research 1986, 244: 21-26. PMID: 2421915, DOI: 10.1007/bf00218377.Peer-Reviewed Original Research
1984
Difference in Calcium Requirements for Forskolin-Induced Release of Prolactin from Normal Pituitary Cells and GH4C1 Cells in Culture*
DELBEKE D, SCAMMELI J, DANNIES P. Difference in Calcium Requirements for Forskolin-Induced Release of Prolactin from Normal Pituitary Cells and GH4C1 Cells in Culture*. Endocrinology 1984, 114: 1433-1440. PMID: 6323146, DOI: 10.1210/endo-114-4-1433.Peer-Reviewed Original ResearchConceptsGH4C1 cellsPRL releaseMale rat pituitary glandPrimary culturesNormal cellsNormal pituitary cellsPresence of D600Release of prolactinRat pituitary glandAddition of forskolinIntracellular cAMP concentrationPituitary tumorsFischer ratsPituitary cellsPituitary glandChannel inhibitorsTumor cellsTypes of cellsAdenylate cyclaseD600ForskolinCAMP concentrationCalcium requirementForskolin stimulationCells
1983
Veratridine and Ouabain Stimulate Calcium-Dependent Prolactin Release*
SCAMMELL J, DANNIES P. Veratridine and Ouabain Stimulate Calcium-Dependent Prolactin Release*. Endocrinology 1983, 113: 1228-1235. PMID: 6617570, DOI: 10.1210/endo-113-4-1228.Peer-Reviewed Original ResearchConceptsPRL releaseCalcium channel blocker D600Rat anterior pituitary cellsTetrodotoxin-insensitive mechanismCalcium channel blockersChannel blocker tetrodotoxinDopaminergic agonist bromocriptineEffect of veratridineAnterior pituitary cellsAction of veratridineChannel blocker D600Blocker tetrodotoxinAgonist bromocriptineProlactin releaseChannel blockersVeratridine effectPituitary cellsChannel activatorVeratridineGH4C1 cellsPrimary culturesOuabainNormal cellsStimulationPreincubation3COMPARISON OF THEEFFECTS OF HISTAMINE H2-RECEPTOR ANTAGONISTS ON PROLACTIN SECRETION IN THE RAT.
NETTI C, GUIDOBONO F, OLGIATI V, SIBILIA V, PECILE A, Dannies P. 3COMPARISON OF THEEFFECTS OF HISTAMINE H2-RECEPTOR ANTAGONISTS ON PROLACTIN SECRETION IN THE RAT. Endocrinology 1983, 113: 412-414. PMID: 6305638, DOI: 10.1210/endo-113-1-412.Peer-Reviewed Original ResearchConceptsPRL releaseHistamine H2-receptor antagonistsSignificant PRL releaseH2-receptor antagonistsCentral neural controlPRL-releasing activityHistamine H2 receptorsPRL secretionBlocking actionProlactin secretionH2 receptorsSingle bolusBlood samplesHigh doseBlocking potencyPrompt increaseBrain ventriclesNeural controlDrugsCimetidineRanitidineRatsStimulating effectPRLSecretion
1981
Muscarinic inhibition of prolactin production in cultures of rat pituitary cells
Rudnick M, Dannies P. Muscarinic inhibition of prolactin production in cultures of rat pituitary cells. Biochemical And Biophysical Research Communications 1981, 101: 689-696. PMID: 7306103, DOI: 10.1016/0006-291x(81)91313-9.Peer-Reviewed Original Research
1980
Dopaminergic inhibition of ionophore A23187-stimulated release of prolactin from rat anterior pituitary cells.
Tam S, Dannies P. Dopaminergic inhibition of ionophore A23187-stimulated release of prolactin from rat anterior pituitary cells. Journal Of Biological Chemistry 1980, 255: 6595-6599. PMID: 6771274, DOI: 10.1016/s0021-9258(18)43611-3.Peer-Reviewed Original ResearchEffects of Estradiol on Prolactin Production and Dihydroergocryptine-Induced Inhibition of Prolactin Production in Primary Cultures of Rat Pituitary Cells*
WEST B, DANNIES P. Effects of Estradiol on Prolactin Production and Dihydroergocryptine-Induced Inhibition of Prolactin Production in Primary Cultures of Rat Pituitary Cells*. Endocrinology 1980, 106: 1108-1113. PMID: 6766855, DOI: 10.1210/endo-106-4-1108.Peer-Reviewed Original Research2-Bromo-alpha-ergocryptine causes degradation of prolactin in primary cultures of rat pituitary cells after chronic treatment.
Dannies P, Rudnick M. 2-Bromo-alpha-ergocryptine causes degradation of prolactin in primary cultures of rat pituitary cells after chronic treatment. Journal Of Biological Chemistry 1980, 255: 2776-2781. PMID: 7358708, DOI: 10.1016/s0021-9258(19)85806-4.Peer-Reviewed Original Research
1979
Antipsychotic Drugs Inhibit Prolactin Release from Rat Anterior Pituitary Cells in Culture by a Mechanism Not Involving the Dopamine Receptor*
WEST B, DANNIES P. Antipsychotic Drugs Inhibit Prolactin Release from Rat Anterior Pituitary Cells in Culture by a Mechanism Not Involving the Dopamine Receptor*. Endocrinology 1979, 104: 877-880. PMID: 436760, DOI: 10.1210/endo-104-4-877.Peer-Reviewed Original ResearchConceptsRat anterior pituitary cellsAnterior pituitary cellsGH releasePRL releaseControl valuesAntipsychotic drugsDopamine antagonistsDopamine receptorsPituitary cellsInhibition of PRLMicroM pimozideDopamine agonistsHormone releaseD-butaclamolInhibited secretionPRLBromocriptineAntagonistButaclamolInhibitionReceptorsDrugsReleaseCellsHaloperidol
1974
Pyroglutamyl-histidyl-prolineamide (TRH). A neurohormone which affects the release and synthesis of prolactin and thyrotropin.
Dannies P, Tashjian A. Pyroglutamyl-histidyl-prolineamide (TRH). A neurohormone which affects the release and synthesis of prolactin and thyrotropin. Israel Medical Association Journal 1974, 10: 1294-304. PMID: 4215776.Peer-Reviewed Original Research