1988
TRH and BAY K 8644 synergistically stimulate prolactin release but not 45Ca2+ uptake
Pachter J, Law G, Dannies P. TRH and BAY K 8644 synergistically stimulate prolactin release but not 45Ca2+ uptake. American Journal Of Physiology 1988, 255: c633-c640. PMID: 2461093, DOI: 10.1152/ajpcell.1988.255.5.c633.Peer-Reviewed Original ResearchConceptsBay K 8644Thyrotropin-releasing hormoneProlactin secretionAngiotensin IIProlactin releaseChannel agonist Bay K 8644Agonist Bay K 8644Rat anterior pituitary cellsFluorescent indicator indo-1Anterior pituitary cellsDihydropyridine-sensitive Ca2Indicator indo-1Primary cultured cellsSecretory peaksPituitary cellsSubsequent stimulationIndo-1Transient increaseCytosolic Ca2GH4C1 cellsPrimary culturesSecretionUntreated cellsAdditional effectCultured cells
1984
Synergistic stimulation of prolactin release by phorbol ester, A23187 and forskolin
Delbeke D, Kojima I, Dannies P, Rasmussen H. Synergistic stimulation of prolactin release by phorbol ester, A23187 and forskolin. Biochemical And Biophysical Research Communications 1984, 123: 735-741. PMID: 6091639, DOI: 10.1016/0006-291x(84)90291-2.Peer-Reviewed Original Research
1983
Tamoxifen and 5-fluorouracil in breast cancer: cytotoxic synergism in vitro.
Benz C, Cadman E, Gwin J, Wu T, Amara J, Eisenfeld A, Dannies P. Tamoxifen and 5-fluorouracil in breast cancer: cytotoxic synergism in vitro. Cancer Research 1983, 43: 5298-303. PMID: 6616464.Peer-Reviewed Original ResearchConceptsHormone-dependent human breast cancer cell linesCytotoxic interactionNuclear estrogen receptor levelsEstrogen receptor levelsHuman breast cancer cell linesBreast cancer cell linesMCF-7Nuclear estrogen receptorsMCF-7 cytotoxicityCytosol progesterone receptorGrowth inhibitionCytosol progesteroneCancer cell linesMCF-7 cellsMicroM tamoxifenProgesterone receptorBreast cancerReceptor levelsEstrogen receptorNM estradiolTamoxifenIsobologram analysisClonogenic assayControl valuesCell lines