1993
Rapid stimulation of rhodamine 123 efflux from multidrug-resistant KB cells by progesterone
Jancis E, Hong-xing C, Carbone R, Hochberg R, Dannies P. Rapid stimulation of rhodamine 123 efflux from multidrug-resistant KB cells by progesterone. Biochemical Pharmacology 1993, 46: 1613-1619. PMID: 7902090, DOI: 10.1016/0006-2952(93)90331-p.Peer-Reviewed Original ResearchConceptsRhodamine 123 effluxMultidrug resistance pumpRhodamine 123Efflux of daunomycinRapid stimulationMultidrug-resistant KB cellsAbsence of progesteroneNon-genomic mechanismsCause of retentionKB cellsMicroM progesteroneProgesteroneCarcinoma cellsPump activityActive steroidsMCF7 cellsStimulationIntracellular bindingEffluxCellsMitochondrial dyeDesoxycorticosteronePromegestoneVerapamilTestosterone
1987
Regulation of Prolactin Production and Cell Growth by Estradiol: Difference in Sensitivity to Estradiol Occurs at Level of Messenger Ribonucleic Acid Accumulation*
AMARA J, VAN ITALLIE C, DANNIES P. Regulation of Prolactin Production and Cell Growth by Estradiol: Difference in Sensitivity to Estradiol Occurs at Level of Messenger Ribonucleic Acid Accumulation*. Endocrinology 1987, 120: 264-271. PMID: 3780563, DOI: 10.1210/endo-120-1-264.Peer-Reviewed Original ResearchConceptsPRL productionMaximal stimulationGH4C1 cellsOrder of potencyMessenger ribonucleic acid accumulationBiological effectsBeta-EstradiolCell growthEstrogen concentrationsProlactin productionEthynyl estradiolFull agonistSame receptorEstradiolStimulationEstrogenPRL mRNAEffective concentrationAnalog potencyPotencyCellsRibonucleic acid accumulationMRNA
1986
Antiestrogens are partial estrogen agonists for prolactin production in primary pituitary cultures
Martinez-Campos A, Amara J, Dannies P. Antiestrogens are partial estrogen agonists for prolactin production in primary pituitary cultures. Molecular And Cellular Endocrinology 1986, 48: 127-133. PMID: 3803705, DOI: 10.1016/0303-7207(86)90035-3.Peer-Reviewed Original ResearchConceptsProlactin productionPituitary cellsMale rat anterior pituitary cellsRat anterior pituitary cellsPartial estrogen agonistNormal pituitary cellsAnterior pituitary cellsConcentrations of estradiolDose-response relationshipPrimary pituitary culturesEstrogen antagonistLY 117018Estrogen agonistM tamoxifenPartial agonistPituitary culturesEstrogen inductionTamoxifenMaximal stimulationFull antagonistM LysPrimary culturesStimulationPimozideAgonists
1983
Veratridine and Ouabain Stimulate Calcium-Dependent Prolactin Release*
SCAMMELL J, DANNIES P. Veratridine and Ouabain Stimulate Calcium-Dependent Prolactin Release*. Endocrinology 1983, 113: 1228-1235. PMID: 6617570, DOI: 10.1210/endo-113-4-1228.Peer-Reviewed Original ResearchConceptsPRL releaseCalcium channel blocker D600Rat anterior pituitary cellsTetrodotoxin-insensitive mechanismCalcium channel blockersChannel blocker tetrodotoxinDopaminergic agonist bromocriptineEffect of veratridineAnterior pituitary cellsAction of veratridineChannel blocker D600Blocker tetrodotoxinAgonist bromocriptineProlactin releaseChannel blockersVeratridine effectPituitary cellsChannel activatorVeratridineGH4C1 cellsPrimary culturesOuabainNormal cellsStimulationPreincubation17β-ESTRADIOL HAS A BIPHASIC EFFECT ON GH CELL GROWTH1
AMARA J, DANNIES P. 17β-ESTRADIOL HAS A BIPHASIC EFFECT ON GH CELL GROWTH1. Endocrinology 1983, 112: 1141-1143. PMID: 6822206, DOI: 10.1210/endo-112-3-1141.Peer-Reviewed Original ResearchConceptsHalf-maximal concentrationGH cellsProlactin productionEffects of estradiolPituitary tumor growthDose-dependent decreaseCell numberHigh oestrogen concentrationsRat pituitary tumor cellsPituitary tumor cellsBeta-EstradiolBiphasic effectEstrogen concentrationsTumor growthEstradiolTumor cellsInhibitory effectMaximal concentrationInhibition of growthBiphasic fashionSerumStimulationCell growthHorse serumCells