17β-ESTRADIOL HAS A BIPHASIC EFFECT ON GH CELL GROWTH1
AMARA J, DANNIES P. 17β-ESTRADIOL HAS A BIPHASIC EFFECT ON GH CELL GROWTH1. Endocrinology 1983, 112: 1141-1143. PMID: 6822206, DOI: 10.1210/endo-112-3-1141.Peer-Reviewed Original ResearchConceptsHalf-maximal concentrationGH cellsProlactin productionEffects of estradiolPituitary tumor growthDose-dependent decreaseCell numberHigh oestrogen concentrationsRat pituitary tumor cellsPituitary tumor cellsBeta-EstradiolBiphasic effectEstrogen concentrationsTumor growthEstradiolTumor cellsInhibitory effectMaximal concentrationInhibition of growthBiphasic fashionSerumStimulationCell growthHorse serumCells