2010
Anti-tumor effects of adenovirus containing human growth hormone sequences in a mouse model of human ovarian cancer
Zhu Y, Fariña JB, Meshack S, Santoveña A, Patel S, Oliva A, Llabrés M, Hodsdon ME, Booth CJ, Dannies PS. Anti-tumor effects of adenovirus containing human growth hormone sequences in a mouse model of human ovarian cancer. Endocrine 2010, 37: 430-439. PMID: 20960164, DOI: 10.1007/s12020-010-9333-5.Peer-Reviewed Original ResearchConceptsHuman ovarian cancerOvarian cancerPeritoneal cavityMouse modelTumor cell injectionImmunodeficient SCID miceGrowth hormone releaseHuman ovarian cancer cellsAnti-tumor effectsOvarian cancer cellsReplication-deficient adenovirusLower survival rateLiver metastasesMedian survivalControl miceLung metastasesIntraperitoneal injectionPeritoneal fibrosisLiver toxicitySCID miceHormone releaseHepatocellular changesSurvival rateCell injectionGrowth hormone
2001
A serum prolactin-binding protein: implications for growth hormone
Dannies P. A serum prolactin-binding protein: implications for growth hormone. Trends In Endocrinology And Metabolism 2001, 12: 427-428. PMID: 11701331, DOI: 10.1016/s1043-2760(01)00497-0.Peer-Reviewed Original Research
2000
Autosomal Dominant Growth Hormone (GH) Deficiency Type II: The Del32–71-GH Deletion Mutant Suppresses Secretion of Wild-Type GH*
Lee M, Wajnrajch M, Kim S, Plotnick L, Wang J, Gertner J, Leibel R, Dannies P. Autosomal Dominant Growth Hormone (GH) Deficiency Type II: The Del32–71-GH Deletion Mutant Suppresses Secretion of Wild-Type GH*. Endocrinology 2000, 141: 883-890. DOI: 10.1210/en.141.3.883.Peer-Reviewed Original ResearchWild-type GHGH deficiency type IIGrowth hormoneWild-type human GHSecretory pathway functionGH deficiencyAutosomal dominant formHuman GHDel32Neuroendocrine cell lineShort statureHuman PRLNormal alleleTransient transfectionCell linesPosttranslational effectWild-typeTransfected COSDecreased synthesisPRLIntracellular stabilityPathway functionCHO cellsType IISuppressed accumulation
1985
Prolactin
Dannies P. Prolactin. 1985, 159-174. DOI: 10.1007/978-1-4684-7018-5_7.Peer-Reviewed Original ResearchSecretion of proteinsRegulation of osmolarityCell biologistsMolecular biologistsHormone actionProlactin productionBiologistsRegulationAnterior pituitary glandVariety of effectsUseful modelHuman growth hormoneHormone productionHuman studiesPituitary glandGrowth hormoneHuman prolactinProteinProlactinReproductionProductionHormoneImportant toolLarge number
1980
Hormonal control of tyrosine aminotransferase, prolactin, and growth hormone induction in somatic cell hybrids
Thompson E, Dannies P, Buckler C, Tashjian A. Hormonal control of tyrosine aminotransferase, prolactin, and growth hormone induction in somatic cell hybrids. The Journal Of Steroid Biochemistry And Molecular Biology 1980, 12: 193-210. PMID: 6106733, DOI: 10.1016/0022-4731(80)90269-1.Peer-Reviewed Original Research
1977
Anti-Estrogenic Compounds Increase Prolactin and Growth Hormone Synthesis in Clonal Strains of Rat Pituitary Cells1
DANNIES P, YEN P, TASHJIAN A. Anti-Estrogenic Compounds Increase Prolactin and Growth Hormone Synthesis in Clonal Strains of Rat Pituitary Cells1. Endocrinology 1977, 101: 1151-1156. PMID: 908269, DOI: 10.1210/endo-101-4-1151.Peer-Reviewed Original Research
1976
A Possible Role of Cyclic AMP in Mediating the Effects of Thyrotropin-Releasing Hormone on Prolactin Release and on Prolactin and Growth Hormone Synthesis in Pituitary Cells in Culture
DANNIES P, GAUTVIK K, TASHJIAN A. A Possible Role of Cyclic AMP in Mediating the Effects of Thyrotropin-Releasing Hormone on Prolactin Release and on Prolactin and Growth Hormone Synthesis in Pituitary Cells in Culture. Endocrinology 1976, 98: 1147-1159. PMID: 177274, DOI: 10.1210/endo-98-5-1147.Peer-Reviewed Original ResearchConceptsThyrotropin-releasing hormoneEffects of TRHProlactin releaseCyclic AMP concentrationGrowth hormone productionProlactin synthesisGH cellsGrowth hormone synthesisCyclic AMPPituitary cellsPhosphodiesterase inhibitorHormone productionHormone synthesisNM thyrotropin-releasing hormoneConcentration of TRHIntracellular cyclic AMP concentrationAMP concentrationCyclic AMP accumulationRat pituitary cellsHalf-maximal increaseDibutyryl cyclic AMPLong-term effectsAMP accumulationGrowth hormoneSerum-free medium
1973
CHAPTER 1 Growth Hormone and Prolactin from Rat Pituitary Tumor Cells11Preparation of this review and the results of original experiments described were supported in part by a research grant from the USPHS (AM 11011). P. S. Dannies is a Postdoctoral Research Fellow of The Arthritis Foundation.
Dannies P, Tashjian A. CHAPTER 1 Growth Hormone and Prolactin from Rat Pituitary Tumor Cells11Preparation of this review and the results of original experiments described were supported in part by a research grant from the USPHS (AM 11011). P. S. Dannies is a Postdoctoral Research Fellow of The Arthritis Foundation. 1973, 561-569. DOI: 10.1016/b978-0-12-427150-0.50128-5.Peer-Reviewed Original ResearchGrowth hormoneRat pituitary tumor cellsPituitary tumor cellsPituitary cellsTumor cellsNormal pituitary cellsMechanism of actionArthritis FoundationIntact animalsComplement fixationProlactinHormoneCell populationsHomogeneous cell populationClonal strainsUseful modelCellsVariety of factorsCell homogenatesMicrocomplement fixationFixationCulture medium