Effects of Thyrotropin-releasing Hormone and Hydrocortisone on Synthesis and Degradation of Prolactin in a Rat Pituitary Cell Strain
Dannies P, Tashjian A. Effects of Thyrotropin-releasing Hormone and Hydrocortisone on Synthesis and Degradation of Prolactin in a Rat Pituitary Cell Strain. Journal Of Biological Chemistry 1973, 248: 6174-6179. PMID: 4199262, DOI: 10.1016/s0021-9258(19)43524-2.Peer-Reviewed Original ResearchConceptsSynthesis of prolactinProlactin accumulationThyrotropin-releasing hormoneHydrocortisone resultsEffect of thyrotropinLong-term effectsPituitary cellsGH cellsProlactinDegradation of prolactinHormoneTerm effectsHydrocortisoneIntracellular poolDecreased accumulationClonal strainsCell strainsRadioactive leucineSpecific immunoprecipitationCellsHoursTreatmentDaysLeucineCulture mediumCHAPTER 1 Growth Hormone and Prolactin from Rat Pituitary Tumor Cells11Preparation of this review and the results of original experiments described were supported in part by a research grant from the USPHS (AM 11011). P. S. Dannies is a Postdoctoral Research Fellow of The Arthritis Foundation.
Dannies P, Tashjian A. CHAPTER 1 Growth Hormone and Prolactin from Rat Pituitary Tumor Cells11Preparation of this review and the results of original experiments described were supported in part by a research grant from the USPHS (AM 11011). P. S. Dannies is a Postdoctoral Research Fellow of The Arthritis Foundation. 1973, 561-569. DOI: 10.1016/b978-0-12-427150-0.50128-5.Peer-Reviewed Original ResearchGrowth hormoneRat pituitary tumor cellsPituitary tumor cellsPituitary cellsTumor cellsNormal pituitary cellsMechanism of actionArthritis FoundationIntact animalsComplement fixationProlactinHormoneCell populationsHomogeneous cell populationClonal strainsUseful modelCellsVariety of factorsCell homogenatesMicrocomplement fixationFixationCulture medium