2024
Living in disadvantaged neighborhoods linked to less intervention for severe aortic stenosis
Ram C, Yousef S, Ma W, Vallabhajosyula I, Singh S, Agarwal R, Milewski R, Assi R, Patel P, Williams M, Geirsson A, Vallabhajosyula P. Living in disadvantaged neighborhoods linked to less intervention for severe aortic stenosis. Scientific Reports 2024, 14: 4952. PMID: 38418864, PMCID: PMC10902341, DOI: 10.1038/s41598-024-52660-w.Peer-Reviewed Original ResearchConceptsAortic valve replacementSevere aortic stenosisAfrican American raceArea Deprivation IndexAortic stenosisSevere ASArea deprivation index rankAortic valve replacement ratesAmerican raceAortic valve interventionPresentation of sepsisDiagnosis of ASADI groupValve replacementValve interventionDeprived neighbourhoodsAV interventionDisadvantaged neighborhoodsPatientsFemale genderDeprivation indexHigh-ADI groupLow-ADI groupStenosisRace
2018
Hemodynamic Effects of Valve Asymmetry in Sapien 3 Transcatheter Aortic Valves.
Mangels DR, Siki M, Menon R, Bavaria J, Anwaruddin S, Giri J, Desai N, Szeto WY, Vallabhajosyula P, Herrmann HC. Hemodynamic Effects of Valve Asymmetry in Sapien 3 Transcatheter Aortic Valves. Journal Of Invasive Cardiology 2018, 30: 138-143. PMID: 29610444.Peer-Reviewed Original ResearchConceptsStructural valve deteriorationTranscatheter aortic valve replacementSAPIEN 3 valveParavalvular leakTransthoracic echocardiogramAortic insufficiencySAPIEN 3 transcatheter aortic valveAortic valve gradientSapien 3 prosthesisAortic valve replacementRetrospective cohort analysisTranscatheter aortic valveAI severityValve gradientAnnular calcificationHemodynamic effectsValve replacementValve deteriorationSmall prosthesisSingle institutionAortic valveAV gradientCohort analysisHigh incidenceSignificant differencesAssociation of Tricuspid Regurgitation With Transcatheter Aortic Valve Replacement Outcomes: A Report From The Society of Thoracic Surgeons/American College of Cardiology Transcatheter Valve Therapy Registry
McCarthy FH, Vemulapalli S, Li Z, Thourani V, Matsouaka RA, Desai ND, Kirtane A, Anwaruddin S, Williams ML, Giri J, Vallabhajosyula P, Li RH, Herrmann HC, Bavaria JE, Szeto WY. Association of Tricuspid Regurgitation With Transcatheter Aortic Valve Replacement Outcomes: A Report From The Society of Thoracic Surgeons/American College of Cardiology Transcatheter Valve Therapy Registry. The Annals Of Thoracic Surgery 2018, 105: 1121-1128. PMID: 29502934, DOI: 10.1016/j.athoracsur.2017.11.018.Peer-Reviewed Original ResearchConceptsTranscatheter aortic valve replacementHeart failure readmissionCardiology Transcatheter Valve Therapy RegistryThoracic Surgeons/American CollegeTranscatheter Valve Therapy RegistrySevere TRVentricular ejection fractionTricuspid regurgitationMild TRRisk patientsEjection fractionTR severityAmerican CollegeEffectiveness of TAVRInhospital major adverse cardiac eventsTranscatheter Aortic Valve Replacement OutcomesModerate TRMajor adverse cardiac eventsTricuspid regurgitation severityAdverse cardiac eventsAortic valve replacementHigh-risk patientsLow-risk patientsNumber of comorbiditiesIntensive care unit
2017
Management of coronary obstruction following transcatheter aortic valve replacement
Sultan I, Siki M, Wallen T, Szeto W, Vallabhajosyula P. Management of coronary obstruction following transcatheter aortic valve replacement. Journal Of Cardiac Surgery 2017, 32: 777-781. PMID: 29143378, DOI: 10.1111/jocs.13252.Peer-Reviewed Original ResearchMeSH KeywordsAged, 80 and overAortic Valve StenosisCoronary OcclusionFemaleHumansPostoperative ComplicationsTranscatheter Aortic Valve ReplacementConceptsTranscatheter aortic valve replacementAortic valve replacementValve replacementCoronary arterySelf-expanding transcatheter aortic valve replacementLeft coronary arteryTAVR casesCoronary ostiumCoronary obstructionHigh riskMortality rateComplicationsArteryOcclusionPreventionManagementReplacementOstiumObstructionMortalityIncidenceConscious Sedation Versus General Anesthesia for Transcatheter Aortic Valve Replacement
Hyman MC, Vemulapalli S, Szeto WY, Stebbins A, Patel PA, Matsouaka RA, Herrmann HC, Anwaruddin S, Kobayashi T, Desai ND, Vallabhajosyula P, McCarthy FH, Li R, Bavaria JE, Giri J. Conscious Sedation Versus General Anesthesia for Transcatheter Aortic Valve Replacement. Circulation 2017, 136: 2132-2140. PMID: 28864443, DOI: 10.1161/circulationaha.116.026656.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAnesthesia, GeneralAortic Valve StenosisComparative Effectiveness ResearchConscious SedationFemaleHospital MortalityHumansIntention to Treat AnalysisLength of StayMalePatient DischargePractice Patterns, Physicians'RegistriesRisk AssessmentRisk FactorsTime FactorsTranscatheter Aortic Valve ReplacementTreatment OutcomeUnited StatesConceptsTranscatheter aortic valve replacementAortic valve replacementConscious sedationIntensive care unitGeneral anesthesiaHospital lengthValve replacementProcedural successCare unitEnd-point analysisPercutaneous transfemoral transcatheter aortic valve replacementConscious Sedation Versus General AnesthesiaTransfemoral transcatheter aortic valve replacementCardiology Transcatheter Valve Therapy RegistryThoracic Surgeons/American CollegeDeath/stroke ratePacemaker/defibrillator implantationTranscatheter Valve Therapy RegistryInverse probabilityConscious sedation groupDeath/strokeTreatment-weighted adjustmentTreatment-weighted analysisLower procedural successComparative effectiveness analysis
2016
New Ventricular Septal Defects Following Balloon-Expandable Transcatheter Aortic Valve Replacement.
Rene AG, Jagasia D, Wickramasinghe SR, Desai N, Szeto W, Vallabhajosyula P, Li RH, Silvestry FE, Giri J, Jha S, Herrmann HC, Anwaruddin S. New Ventricular Septal Defects Following Balloon-Expandable Transcatheter Aortic Valve Replacement. Journal Of Invasive Cardiology 2016, 28: e59-65. PMID: 27342207.Peer-Reviewed Original ResearchMeSH KeywordsAged, 80 and overAortic ValveAortic Valve StenosisEchocardiographyFemaleHeart Septal Defects, VentricularHumansMaleOutcome and Process Assessment, Health CarePostoperative ComplicationsQuality of LifeReoperationRisk AssessmentRisk FactorsSeverity of Illness IndexTranscatheter Aortic Valve ReplacementConceptsTranscatheter aortic valve replacementLeft ventricular outflow tract calcificationSevere symptomatic aortic stenosisVentricular outflow tract calcificationSymptomatic aortic stenosisAortic valve replacementVentricular septal defectNew ventricular septal defectQuality of lifeInoperable patientsInfrequent complicationParavalvular regurgitationValve replacementAortic stenosisVascular injurySeptal defectPatientsComplicationsStudied populationRegurgitationStenosisInjuryStrokeCalcificationTransfemoral transcatheter valve-in-valve-in-valve replacement
Sang S, Giri J, Vallabhajosyula P. Transfemoral transcatheter valve-in-valve-in-valve replacement. Journal Of Thoracic And Cardiovascular Surgery 2016, 152: 622-623. PMID: 27179844, DOI: 10.1016/j.jtcvs.2016.03.047.Peer-Reviewed Original ResearchTranscatheter Aortic Valve Replacement: Clinical Update on Access Approaches in the Contemporary Era
Ramakrishna H, Patel PA, Gutsche JT, Vallabhajosyula P, Spitz W, Feinman JW, Shah R, Zhou E, Weiss SJ, Augoustides JG. Transcatheter Aortic Valve Replacement: Clinical Update on Access Approaches in the Contemporary Era. Journal Of Cardiothoracic And Vascular Anesthesia 2016, 30: 1425-1429. PMID: 27468895, DOI: 10.1053/j.jvca.2016.03.006.Peer-Reviewed Educational Materials
2015
Outcomes of transcatheter aortic valve replacement in patients with chronic liver disease
Shah AM, Ogbara J, Herrmann HC, Fox Z, Kadakia M, Anwaruddin S, Bavaria JE, Desai ND, Jagasia D, Szeto WY, Li RH, Vallabhajosyula P, Giri J. Outcomes of transcatheter aortic valve replacement in patients with chronic liver disease. Catheterization And Cardiovascular Interventions 2015, 86: 888-894. PMID: 25963625, DOI: 10.1002/ccd.25994.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAortic ValveAortic Valve StenosisBioprosthesisBiopsyCardiac CatheterizationChronic DiseaseFeasibility StudiesFemaleFemoral ArteryHeart Valve ProsthesisHeart Valve Prosthesis ImplantationHospital MortalityHumansLiver DiseasesMaleMiddle AgedPatient SelectionRetrospective StudiesRisk AssessmentRisk FactorsSeverity of Illness IndexTime FactorsTreatment OutcomeConceptsTranscatheter aortic valve replacementChronic liver diseaseValve Academic Research ConsortiumAcute kidney injuryAortic valve replacementLiver diseaseLate deathsKidney injuryValve replacementUnknown causeTransapical (TA) TAVRRole of TAVRTA TAVRSevere symptomatic aortic valve stenosisModerate chronic liver diseaseSymptomatic aortic valve stenosisAdvanced liver diseaseMajor bleeding complicationsNon-cardiac causesOutcomes of patientsTransient ischemic attackAcademic Research ConsortiumHigh-risk surgeryAortic valve stenosisLong-term followOverestimation of Paravalvular Leak With Edwards SAPIEN 3 Transcatheter Aortic Valve Replacement
Kobayashi T, Giri J, Vallabhajosyula P, Herrmann HC, Jagasia DH. Overestimation of Paravalvular Leak With Edwards SAPIEN 3 Transcatheter Aortic Valve Replacement. JACC Cardiovascular Interventions 2015, 8: e69-e71. PMID: 25946455, DOI: 10.1016/j.jcin.2014.11.027.Peer-Reviewed Original ResearchAged, 80 and overAortic ValveAortic Valve InsufficiencyAortic Valve StenosisAortographyCardiac CatheterizationDiagnostic ErrorsEchocardiography, Doppler, ColorFemaleHeart Valve ProsthesisHeart Valve Prosthesis ImplantationHumansPredictive Value of TestsProsthesis DesignReproducibility of ResultsSeverity of Illness IndexTomography, X-Ray ComputedTreatment Outcome
2014
Combined Transaortic Transcatheter Valve Replacement and Thoracic Endografting
Komlo CM, Vallabhajosyula P, Bavaria JE, Desai ND, Anwaruddin S, Giri JS, Herrmann HC, Szeto WY. Combined Transaortic Transcatheter Valve Replacement and Thoracic Endografting. The Annals Of Thoracic Surgery 2014, 97: 696-698. PMID: 24484814, DOI: 10.1016/j.athoracsur.2013.05.099.Peer-Reviewed Original ResearchConceptsTranscatheter aortic valve replacementThoracic aortic endovascular repairPercutaneous coronary interventionAortic stenosisValve replacementAortic endovascular repairSevere aortic stenosisAortic valve replacementCritical aortic stenosisCatheter-based treatmentThoracic aortic aneurysmTranscatheter valve replacementPartial sternotomy approachCatheter-based proceduresTAo accessCoronary interventionEndovascular repairTransaortic approachTransfemoral accessSternotomy approachAortic aneurysmThoracic endograftingFirst reportEndograftingStenosis
2013
Moderate mitral regurgitation in aortic root replacement surgery: Comparing mitral repair with no mitral repair
McCarthy FH, Desai ND, Fox Z, George J, Moeller P, Vallabhajosyula P, Szeto WY, Bavaria JE. Moderate mitral regurgitation in aortic root replacement surgery: Comparing mitral repair with no mitral repair. Journal Of Thoracic And Cardiovascular Surgery 2013, 147: 938-941. PMID: 24035374, DOI: 10.1016/j.jtcvs.2013.07.056.Peer-Reviewed Original ResearchMeSH KeywordsAortic Valve InsufficiencyAortic Valve StenosisComorbidityHeart FailureHeart Valve Prosthesis ImplantationHumansIncidenceMitral Valve InsufficiencyPatient SelectionPennsylvaniaPostoperative ComplicationsRetrospective StudiesRisk FactorsSeverity of Illness IndexTime FactorsTreatment OutcomeConceptsAortic root replacement surgeryModerate mitral regurgitationMitral repair groupAortic root replacementMitral regurgitationMitral repairReplacement surgeryRoot replacementRepair groupNew York Heart Association III/IVAcceptable operative riskGreater mitral regurgitationPreoperative mitral regurgitationPostoperative renal failureMitral valve pathologyMitral valve repairLong-term survivalBenefits of interventionsCrossclamp timeMitral reinterventionOperative riskRenal failureHeart failureValve pathologyValve repair
2012
Percutaneous Closure of a Left Ventricular Pseudoaneurysm After Sapien XT Transapical Transcatheter Aortic Valve Replacement
Bortnick AE, Gordon E, Gutsche J, Anwaruddin S, Szeto WY, Desai N, Vallabhajosyula P, Bavaria JE, Herrmann HC. Percutaneous Closure of a Left Ventricular Pseudoaneurysm After Sapien XT Transapical Transcatheter Aortic Valve Replacement. JACC Cardiovascular Interventions 2012, 5: e37-e38. PMID: 23257383, DOI: 10.1016/j.jcin.2012.08.014.Peer-Reviewed Original ResearchMeSH KeywordsAged, 80 and overAneurysm, FalseAortic Valve StenosisCardiac CatheterizationFemaleHeart AneurysmHeart Valve Prosthesis ImplantationHumans
2011
Transcatheter aortic valve implantation: complications and management.
Vallabhajosyula P, Bavaria JE. Transcatheter aortic valve implantation: complications and management. The Journal Of Heart Valve Disease 2011, 20: 499-509. PMID: 22066353.Peer-Reviewed Original ResearchMeSH KeywordsAortic AneurysmAortic DissectionAortic Valve StenosisBioprosthesisCardiac CatheterizationCardiopulmonary BypassClinical CompetenceHeart Valve ProsthesisHeart Valve Prosthesis ImplantationHumansHypotensionIliac ArteryMyocardial IschemiaPatient Care TeamPostoperative ComplicationsProsthesis FittingStrokeConceptsTranscatheter aortic valve implantationAortic valve replacementSerious life-threatening complicationsImmediate cardiopulmonary bypassPoor surgical candidatesSevere aortic stenosisLife-threatening complicationsAortic valve implantationAnnulus injuryCoronary complicationsPerfusion teamTAVI patientsValve malpositionCardiac depressionPericardial effusionSurgical candidatesValve implantationValve replacementAortic stenosisCardiopulmonary bypassSerious complicationsParavalvular leakOptimal careVascular injuryCardiac anesthesia