2024
Clinical Effectiveness of Genetic Testing Guidelines in Patients with Thoracic Aortic Aneurysms
Erez E, Acuna Higaki A, Cupo M, Phu T, Verma S, Assi R, Vallabhajosyula P. Clinical Effectiveness of Genetic Testing Guidelines in Patients with Thoracic Aortic Aneurysms. Journal Of Thoracic And Cardiovascular Surgery 2024 PMID: 39321868, DOI: 10.1016/j.jtcvs.2024.09.026.Peer-Reviewed Original ResearchFeatures of connective tissue diseaseThoracic aortic diseaseConnective tissue diseaseThoracic aortic aneurysmGenetic testing guidelinesSyndromic featuresMutation rateFamily historyVUS rateAortic aneurysmPrimary genesGenetic testingAssociated with thoracic aortic diseaseThoracic aorta diameterTesting guidelinesAorta diameterPathogen mutation rateAortic diseaseRisk stratificationSecondary genesPathogenic mutationsTissue diseaseClinical effectsVUSGenesThoracic endovascular aneurysm repair of a ruptured zone 0 mycotic thoracic aortic aneurysm
Kostiuk V, Vallabhajosyula P, Nassiri N, Tonnessen B. Thoracic endovascular aneurysm repair of a ruptured zone 0 mycotic thoracic aortic aneurysm. Annals Of Vascular Surgery - Brief Reports And Innovations 2024, 4: 100302. DOI: 10.1016/j.avsurg.2024.100302.Peer-Reviewed Original ResearchThoracic endovascular aneurysm repairEndovascular aneurysm repairAneurysm repairAcute type B aortic dissectionAcute onset chest painWeeks of antibiotic treatmentType B aortic dissectionAnti-impulse therapyExclusion of hemorrhageOnset chest painAortic arch debranchingPost-operative courseB aortic dissectionComputed tomography angiogramThoracic aortic aneurysmZone 0 TEVARArch debranchingMediastinal infectionChest painContrast extravasationBack painAntibiotic treatmentAortic aneurysmPost-operativelyFollow-up
2017
Fate of remnant sinuses of Valsalva in patients with bicuspid and trileaflet valves undergoing aortic valve, ascending aorta, and aortic arch replacement
Milewski RK, Habertheuer A, Bavaria JE, Siki M, Szeto WY, Krause E, Korutla V, Desai ND, Vallabhajosyula P. Fate of remnant sinuses of Valsalva in patients with bicuspid and trileaflet valves undergoing aortic valve, ascending aorta, and aortic arch replacement. Journal Of Thoracic And Cardiovascular Surgery 2017, 154: 421-432. PMID: 28599977, DOI: 10.1016/j.jtcvs.2017.03.150.Peer-Reviewed Original ResearchConceptsAortic valve replacementBicuspid aortic valveAorta replacementTricuspid aortic valveValve replacementAortic valveValsalva dimensionsPreoperative sinusSinus segmentValvular morphologyValvular pathologyElective aortic valve replacementMultivariable Cox regression modelsAortic arch replacementKaplan-Meier analysisAortic valve morphologyCox regression modelAortic valvulopathyArch replacementSurgical managementAortic aneurysmAortic rootLongitudinal sinusValsalva groupPatients
2016
At the Root of the Repair Debate: Outcomes After Elective Aortic Root Replacements for Aortic Insufficiency With Aneurysm
McCarthy FH, Bavaria JE, McDermott KM, Moeller P, Spragan D, Hoedt A, Dibble T, Savino D, Williams ML, Vallabhajosyula P, Szeto WY, Desai ND. At the Root of the Repair Debate: Outcomes After Elective Aortic Root Replacements for Aortic Insufficiency With Aneurysm. The Annals Of Thoracic Surgery 2016, 102: 1199-1205. PMID: 27261085, DOI: 10.1016/j.athoracsur.2016.03.071.Peer-Reviewed Original ResearchMeSH KeywordsAdultAortic Aneurysm, ThoracicAortic Valve InsufficiencyBlood Vessel Prosthesis ImplantationCause of DeathDatabases, FactualElective Surgical ProceduresFemaleFollow-Up StudiesHeart Valve Prosthesis ImplantationHospital MortalityHumansKaplan-Meier EstimateMaleMiddle AgedPostoperative ComplicationsRetrospective StudiesRisk AssessmentSurvival AnalysisTreatment OutcomeConceptsModerate aortic insufficiencySevere aortic insufficiencyAortic insufficiencyLong-term survivalRoot replacementWorse survivalAI patientsDecreased long-term survivalElective aortic root replacementWorse long-term survivalPreoperative aortic insufficiencyPreoperative renal failureAortic root replacementAppropriate therapeutic strategiesGreater aortic insufficiencyTiming of interventionUnited States populationRenal failureYounger patientsMultivariable predictorsSimilar patientsAortic aneurysmSingle institutionInclusion criteriaSimilar survival
2014
Combined Transaortic Transcatheter Valve Replacement and Thoracic Endografting
Komlo CM, Vallabhajosyula P, Bavaria JE, Desai ND, Anwaruddin S, Giri JS, Herrmann HC, Szeto WY. Combined Transaortic Transcatheter Valve Replacement and Thoracic Endografting. The Annals Of Thoracic Surgery 2014, 97: 696-698. PMID: 24484814, DOI: 10.1016/j.athoracsur.2013.05.099.Peer-Reviewed Original ResearchConceptsTranscatheter aortic valve replacementThoracic aortic endovascular repairPercutaneous coronary interventionAortic stenosisValve replacementAortic endovascular repairSevere aortic stenosisAortic valve replacementCritical aortic stenosisCatheter-based treatmentThoracic aortic aneurysmTranscatheter valve replacementPartial sternotomy approachCatheter-based proceduresTAo accessCoronary interventionEndovascular repairTransaortic approachTransfemoral accessSternotomy approachAortic aneurysmThoracic endograftingFirst reportEndograftingStenosis