2014
Lessons learned from extracorporeal membrane oxygenation as a bridge to lung transplantation
Shumaster V, Jawitz O, Yuh D, Bonde P. Lessons learned from extracorporeal membrane oxygenation as a bridge to lung transplantation. ScienceOpen Research 2014, 0 DOI: 10.14293/a2199-1006.01.sor-med.bg1r6.v1.Peer-Reviewed Original ResearchExtracorporeal membrane oxygenationLung transplantationECMO groupPostoperative complicationsMembrane oxygenationUse of ECMOSurvival rateOutcomes of patientsFrequent postoperative complicationOrgan Sharing databaseCareful patient selectionAirway dehiscenceRejection episodesECMO supportHospital stayLung transplantUNOS databasePulmonary embolismWorse survivalSharing databasePatient selectionUnited NetworkTransplantationControl groupComplicationsLessons learned from extracorporeal membrane oxygenation as a bridge to lung transplantation
Shumaster V, Jawitz O, Yuh D, Bonde P. Lessons learned from extracorporeal membrane oxygenation as a bridge to lung transplantation. ScienceOpen Research 2014 DOI: 10.14293/s2199-1006.1.sor-med.abg1r6.v1.Peer-Reviewed Original ResearchExtracorporeal membrane oxygenationLung transplantationECMO groupPostoperative complicationsMembrane oxygenationUse of ECMOSurvival rateOutcomes of patientsFrequent postoperative complicationOrgan Sharing databaseCareful patient selectionAirway dehiscenceRejection episodesECMO supportHospital stayLung transplantUNOS databasePulmonary embolismWorse survivalSharing databasePatient selectionUnited NetworkTransplantationControl groupComplications
2011
Risk-Benefit Tradeoffs in Lung Volume Reduction Surgery as a Bridge to Lung Transplantation for End-Stage Emphysema
Shigemura N, Gilbert S, Bhama J, Bansal A, Bonde P, Bermudez C, Gries C, Crespo M, Johnson B, Pilewski J, Luketich J, Toyoda Y. Risk-Benefit Tradeoffs in Lung Volume Reduction Surgery as a Bridge to Lung Transplantation for End-Stage Emphysema. CHEST Journal 2011, 140: 668a-668b. DOI: 10.1378/chest.1118056.Peer-Reviewed Original ResearchVeno-Venous Extracorporeal Membrane Oxygenation Works for Primary Graft Failure in Lung Transplantation - A Large Single Center Experienc
Toyoda Y, Bhama J, Shigemura N, Bonde P, Bansal A, Crespo M, Pilewski J, Bermudez C. Veno-Venous Extracorporeal Membrane Oxygenation Works for Primary Graft Failure in Lung Transplantation - A Large Single Center Experienc. CHEST Journal 2011, 140: 1022a. DOI: 10.1378/chest.1118126.Peer-Reviewed Original ResearchSuccessful Lung Retransplantation After Extended Use of Extracorporeal Membrane Oxygenation as a Bridge
Shigemura N, Bermudez C, Bhama J, Bonde P, Thacker J, Toyoda Y. Successful Lung Retransplantation After Extended Use of Extracorporeal Membrane Oxygenation as a Bridge. Transplantation Proceedings 2011, 43: 2063-2065. PMID: 21693326, DOI: 10.1016/j.transproceed.2011.02.008.Peer-Reviewed Original ResearchConceptsEarly allograft dysfunctionExtracorporeal membrane oxygenationLung transplantationAllograft dysfunctionMembrane oxygenationRedo lung transplantationAcute cellular rejectionDouble lung transplantationSingle lung transplantationMajor clinical challengeCellular rejectionLung retransplantationClinical challengeSuccessful outcomeTransplantationPatientsDysfunctionOxygenationSuccessful useExtended useRetransplantation446 Cardiopulmonary Bypass and Outcomes of Lung Transplantation in the Modern Era: “To Pump or Not to Pump”
Bermudez C, Jarido V, Toyoda Y, Zaldonis D, Pilewski J, Bhama J, Johnson B, Shigemura N, Bonde P, Gries C, Crespo M. 446 Cardiopulmonary Bypass and Outcomes of Lung Transplantation in the Modern Era: “To Pump or Not to Pump”. The Journal Of Heart And Lung Transplantation 2011, 30: s152. DOI: 10.1016/j.healun.2011.01.455.Peer-Reviewed Original Research315 Donors with Smoking History Have Better Long-Term Outcomes Than with No Smoking History in Adult Lung Transplantation
Shigemura N, Bhama J, Bonde P, Thacker J, Bermudez C, Sareyyupoglu B, Bansal A, Minakata K, Shayan H, Ohta T, Fujimoto K, Crespo M, Johnson B, Pilewski J, Toyoda Y. 315 Donors with Smoking History Have Better Long-Term Outcomes Than with No Smoking History in Adult Lung Transplantation. The Journal Of Heart And Lung Transplantation 2011, 30: s109. DOI: 10.1016/j.healun.2011.01.322.Peer-Reviewed Original Research
2010
428: Initial Experience with Concomitant Surgery of Lung Transplantation and Tricuspid Valve Repair for Patients with Severe Pulmonary Hypertension
Shigemura N, Sareyyupoglu B, Tabata S, Horai T, Bonde P, Crespo M, Johnson B, Pilewski J, Bhama J, Gilbert S, Bermudez C, Toyoda Y. 428: Initial Experience with Concomitant Surgery of Lung Transplantation and Tricuspid Valve Repair for Patients with Severe Pulmonary Hypertension. The Journal Of Heart And Lung Transplantation 2010, 29: s141-s142. DOI: 10.1016/j.healun.2009.11.443.Peer-Reviewed Original Research
2006
DNA damage and mismatch repair pathway in lung ischemia and reperfusion injury
Bonde P, Gao D, Chen L, Moreno-Vinasco L, Jacobson J, Garcia J, Wei C. DNA damage and mismatch repair pathway in lung ischemia and reperfusion injury. Journal Of Cardiothoracic-Renal Research 2006, 1: 147-152. DOI: 10.1016/j.jccr.2006.05.007.Peer-Reviewed Original ResearchLung ischemiaLung transplantationReperfusion groupReperfusion injuryWestern blotDNA mismatch repair pathwayAdult Sprague-Dawley ratsMismatch repair pathwaySprague-Dawley ratsModel of ischemiaAttractive therapeutic interventionCaspase-3 immunohistochemistryDNA damageCaspase-3 levelsDawley ratsLung tissueOxidative DNA damageReperfusionDNA repair enzymeIschemiaTherapeutic interventionsImmunohistochemistryRepair pathwaysProtein levelsTransplantation71 SIMVASTATIN ATTENUATES ACUTE LUNG INJURY INDUCED BY ISCHEMIA-REPERFUSION IN RODENTS.
Moreno L, Jacobson J, Bonde P, Garcia J. 71 SIMVASTATIN ATTENUATES ACUTE LUNG INJURY INDUCED BY ISCHEMIA-REPERFUSION IN RODENTS. Journal Of Investigative Medicine 2006, 54: s355. DOI: 10.2310/6650.2005.x0015.70.Peer-Reviewed Original ResearchIR injuryLung injuryAnimal modelsACUTE LUNG INJURY INDUCEDLung tissue myeloperoxidase activityBronchoalveolar lavage cell countsIschemia-reperfusion lung injuryIndices of inflammationIR lung injuryLavage cell countsLung preservation techniquesTissue myeloperoxidase activityHours of reperfusionLeft pulmonary arteryPotential therapeutic roleAnesthetized Sprague-DawleySignificant clinical impactProfound clinical implicationsLung transplantationTissue MPOAlveolar damageMyeloperoxidase activityTransplant failurePulmonary arterySimvastatin treatment
2005
56 ATTENUATION OF RODENT LUNG ISCHEMIA/REPERFUSION INJURY BY SPHINGOSINE 1-PHOSPHATE
Moreno-Vinasco L, Bonde P, Jacobson J, Garcia J. 56 ATTENUATION OF RODENT LUNG ISCHEMIA/REPERFUSION INJURY BY SPHINGOSINE 1-PHOSPHATE. Journal Of Investigative Medicine 2005, 53: s366. DOI: 10.2310/6650.2005.00206.55.Peer-Reviewed Original ResearchIschemia/reperfusion injuryR injuryMyeloperoxidase activityLung transplantationReperfusion injuryVascular permeabilityAlbumin concentrationLung ischemia/reperfusion injuryLung tissue myeloperoxidase activityBronchoalveolar lavage cell countsLavage cell countsLung preservation techniquesPulmonary artery ligationR lung injuryTissue myeloperoxidase activityTime of reperfusionPeriod of reperfusionLung vascular permeabilityPotential therapeutic roleSprague-Dawley ratsImproved patient outcomesNovel therapeutic interventionsProfound clinical implicationsAlveolar damageDonor lungs